dopamine receptor 2

詳細情報を見る

同義遺伝子名

dopamine receptor 2, Drd2, Drd-2, Dopamine D2 receptor, D2R, D(2) dopamine receptor, D2 receptor

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:3.50

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:32.10

目:7.60

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

GeneChip

大脳:6.51

小脳:4.96

脳幹:-

脳梁:-

松果体:-

末梢神経:4.96

脊柱:6.57

網膜:5.71

目:5.44

動脈:-

静脈:4.74

リンパ節:4.36

末梢血:-

脾臓:4.54

胸腺:-

骨髄:4.69

脂肪:4.70

骨:4.69

皮膚:4.77

CAGE

大脳:0.99

小脳:-

脳幹:3.07

脳梁:-

松果体:-

末梢神経:-

脊柱:2.77

網膜:-

目:-

動脈:0

静脈:-

リンパ節:0

末梢血:-

脾臓:0

胸腺:0

骨髄:-

脂肪:-

骨:0

皮膚:0

RNA-seq

大脳:5.78

小脳:5.78

脳幹:5.78

脳梁:5.78

松果体:5.78

末梢神経:5.78

脊柱:5.78

網膜:5.78

目:5.78

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:-

肝臓:-

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

GeneChip

子宮:4.46

胎盤:5.01

前立腺:4.67

卵巣:4.43

精巣:5.52

心臓:5.74

骨格筋:5.17

食道:-

胃:4.78

腸:4.66

結腸:-

肝臓:5.57

肺:4.60

膀胱:4.48

腎臓:4.88

下垂体:9.56

甲状腺:-

副腎:5.55

膵臓:5.21

乳腺:4.81

唾液腺:4.80

CAGE

子宮:0.17

胎盤:0.11

前立腺:0.74

卵巣:0

精巣:0

心臓:-

骨格筋:-

食道:-

胃:0

腸:0

結腸:0

肝臓:0

肺:0

膀胱:0.46

腎臓:-

下垂体:4.89

甲状腺:-

副腎:1.22

膵臓:0

乳腺:0

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:-

肝臓:-

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_010077
Gene ID	13489
Unigene ID	Mm.41970
Probe set ID	1418950_at [Mouse430_2]
Ensembl ID	ENSMUSG00000032259

オーソログ対応遺伝子

ヒト[8]	NM_000795, NM_016574
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR001922	Dopamine D2 receptor
IPR000929	Dopamine receptor
IPR017452	GPCR, rhodopsin-like superfamily

遺伝子オントロジー (GO ID)

Biological Process

GO:0046717	acid secretion
GO:0060158	activation of phospholipase C activity by dopamine receptor signaling pathway
GO:0032147	activation of protein kinase activity
GO:0021984	adenohypophysis development
GO:0030534	adult behavior
GO:0007628	adult walking behavior
GO:0050482	arachidonic acid secretion
GO:0008306	associative learning
GO:0031223	auditory behavior
GO:0007409	axonogenesis
GO:0048148	behavioral response to cocaine
GO:0048149	behavioral response to ethanol
GO:0048755	branching morphogenesis of a nerve
GO:0021853	cerebral cortex GABAergic interneuron migration
GO:0032922	circadian regulation of gene expression
GO:0042417	dopamine metabolic process
GO:0007212	dopamine receptor signaling pathway
GO:0051482	elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
GO:0007631	feeding behavior
GO:0030900	forebrain development
GO:0002031	G-protein coupled receptor internalization
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0007188	G-protein signaling, coupled to cAMP nucleotide second messenger
GO:0007625	grooming behavior
GO:0007195	inhibition of adenylate cyclase activity by dopamine receptor signaling pathway
GO:0007626	locomotory behavior
GO:0007616	long-term memory
GO:0007194	negative regulation of adenylate cyclase activity
GO:0045776	negative regulation of blood pressure
GO:0030336	negative regulation of cell migration
GO:0008285	negative regulation of cell proliferation
GO:0042321	negative regulation of circadian sleep/wake cycle, sleep
GO:0060160	negative regulation of dopamine receptor signaling pathway
GO:0033602	negative regulation of dopamine secretion
GO:0046676	negative regulation of insulin secretion
GO:0051898	negative regulation of protein kinase B signaling cascade
GO:0050709	negative regulation of protein secretion
GO:0051967	negative regulation of synaptic transmission, glutamatergic
GO:0007270	nerve-nerve synaptic transmission
GO:0001976	neurological system process involved in regulation of systemic arterial blood pressure
GO:0030432	peristalsis
GO:0046488	phosphatidylinositol metabolic process
GO:0043473	pigmentation
GO:0051586	positive regulation of dopamine uptake
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
GO:0060124	positive regulation of growth hormone secretion
GO:0040018	positive regulation of multicellular organism growth
GO:0002052	positive regulation of neuroblast proliferation
GO:0002092	positive regulation of receptor internalization
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0060134	prepulse inhibition
GO:0007243	protein kinase cascade
GO:0008104	protein localization
GO:0051481	reduction of cytosolic calcium ion concentration
GO:0030814	regulation of cAMP metabolic process
GO:0014059	regulation of dopamine secretion
GO:0051584	regulation of dopamine uptake
GO:0002027	regulation of heart rate
GO:0048169	regulation of long-term neuronal synaptic plasticity
GO:0043408	regulation of MAPKKK cascade
GO:0043666	regulation of phosphoprotein phosphatase activity
GO:0043266	regulation of potassium ion transport
GO:0002028	regulation of sodium ion transport
GO:0051823	regulation of synapse structural plasticity
GO:0050804	regulation of synaptic transmission
GO:0032228	regulation of synaptic transmission, GABAergic
GO:0051209	release of sequestered calcium ion into cytosol
GO:0001975	response to amphetamine
GO:0042220	response to cocaine
GO:0042493	response to drug
GO:0034776	response to histamine
GO:0001666	response to hypoxia
GO:0009416	response to light stimulus
GO:0043278	response to morphine
GO:0007608	sensory perception of smell
GO:0007165	signal transduction
GO:0001964	startle response
GO:0001963	synaptic transmission, dopaminergic
GO:0001659	temperature homeostasis
GO:0008542	visual learning
GO:0016055	Wnt receptor signaling pathway

Cellular Component

GO:0001669	acrosomal vesicle
GO:0030424	axon
GO:0031410	cytoplasmic vesicle
GO:0030425	dendrite
GO:0043197	dendritic spine
GO:0030139	endocytic vesicle
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0016328	lateral plasma membrane
GO:0016020	membrane
GO:0043679	nerve terminal
GO:0043204	perikaryon
GO:0005886	plasma membrane
GO:0014069	postsynaptic density
GO:0030672	synaptic vesicle membrane

Molecular Function

GO:0035240	dopamine binding
GO:0004952	dopamine receptor activity
GO:0001591	dopamine receptor activity, coupled via Gi/Go
GO:0008144	drug binding
GO:0004930	G-protein coupled receptor activity
GO:0035255	ionotropic glutamate receptor binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity
GO:0005102	receptor binding
GO:0004871	signal transducer activity

dopamine receptor 2

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function