endothelin 1

詳細情報を見る

同義遺伝子名

ET-1, PPET1, Preproendothelin-1, Endothelin-1 precursor, Edn1, endothelin 1, preproET

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:19.10

小脳:18.40

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:141.90

網膜:-

目:15.20

動脈:421.90

静脈:-

リンパ節:-

末梢血:14.40

脾臓:-

胸腺:9.90

骨髄:435.90

脂肪:-

骨:-

皮膚:15.80

GeneChip

大脳:5.78

小脳:5.92

脳幹:-

脳梁:-

松果体:-

末梢神経:5.68

脊柱:6.08

網膜:5.66

目:6.90

動脈:-

静脈:8.41

リンパ節:5.48

末梢血:-

脾臓:5.66

胸腺:-

骨髄:5.50

脂肪:6.66

骨:5.55

皮膚:6.46

CAGE

大脳:1.42

小脳:-

脳幹:1.80

脳梁:-

松果体:-

末梢神経:-

脊柱:1.73

網膜:-

目:-

動脈:2.61

静脈:-

リンパ節:1.28

末梢血:-

脾臓:0.41

胸腺:1.17

骨髄:-

脂肪:-

骨:0

皮膚:2.95

RNA-seq

大脳:1.10

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:43.60

胎盤:-

前立腺:-

卵巣:-

精巣:29.60

心臓:18.60

骨格筋:-

食道:-

胃:-

腸:-

結腸:52.90

肝臓:-

肺:30.10

膀胱:132.40

腎臓:-

下垂体:-

甲状腺:112.50

副腎:-

膵臓:-

乳腺:9.80

唾液腺:-

GeneChip

子宮:7.25

胎盤:6.74

前立腺:7.18

卵巣:6.55

精巣:5.71

心臓:6.36

骨格筋:6.45

食道:-

胃:6.44

腸:6.75

結腸:-

肝臓:5.92

肺:8.59

膀胱:6.12

腎臓:6.32

下垂体:5.52

甲状腺:-

副腎:5.76

膵臓:6.52

乳腺:6.96

唾液腺:7.06

CAGE

子宮:3.53

胎盤:2.29

前立腺:1.46

卵巣:2.61

精巣:0.75

心臓:-

骨格筋:-

食道:-

胃:2.90

腸:1.22

結腸:1.34

肝臓:0.78

肺:4.23

膀胱:2.33

腎臓:-

下垂体:0.29

甲状腺:-

副腎:1.17

膵臓:2.19

乳腺:1.48

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.01

食道:-

胃:-

腸:-

結腸:-

肝臓:1.68

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_010104
Gene ID	13614
Unigene ID	Mm.14543
Probe set ID	1451924_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000021367

オーソログ対応遺伝子

ヒト[4]	NM_001168319, NM_001955
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR020475	Bibrotoxin/Sarafotoxin-D
IPR001928	Endothelin-like toxin

遺伝子オントロジー (GO ID)

Biological Process

GO:0031583	activation of phospholipase D activity by G-protein coupled receptor protein signaling pathway
GO:0007205	activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway
GO:0014824	artery smooth muscle contraction
GO:0048514	blood vessel morphogenesis
GO:0007589	body fluid secretion
GO:0019722	calcium-mediated signaling
GO:0051216	cartilage development
GO:0016049	cell growth
GO:0007166	cell surface receptor linked signal transduction
GO:0007267	cell-cell signaling
GO:0009953	dorsal/ventral pattern formation
GO:0007204	elevation of cytosolic calcium ion concentration
GO:0051482	elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
GO:0042045	epithelial fluid transport
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0015758	glucose transport
GO:0007507	heart development
GO:0001821	histamine secretion
GO:0001701	in utero embryonic development
GO:0048016	inositol phosphate-mediated signaling
GO:0051899	membrane depolarization
GO:0042474	middle ear morphogenesis
GO:0030818	negative regulation of cAMP biosynthetic process
GO:0032269	negative regulation of cellular protein metabolic process
GO:0046888	negative regulation of hormone secretion
GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process
GO:0034392	negative regulation of smooth muscle cell apoptosis
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0014032	neural crest cell development
GO:0030185	nitric oxide transport
GO:0001569	patterning of blood vessels
GO:0030072	peptide hormone secretion
GO:0014065	phosphoinositide 3-kinase cascade
GO:0010613	positive regulation of cardiac muscle hypertrophy
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0045793	positive regulation of cell size
GO:0010460	positive regulation of heart rate
GO:0046887	positive regulation of hormone secretion
GO:0043507	positive regulation of JUN kinase activity
GO:0043406	positive regulation of MAP kinase activity
GO:0045840	positive regulation of mitosis
GO:0090023	positive regulation of neutrophil chemotaxis
GO:0042482	positive regulation of odontogenesis
GO:0060585	positive regulation of prostaglandin-endoperoxidase synthase activity
GO:0010870	positive regulation of receptor biosynthetic process
GO:0060298	positive regulation of sarcomere organization
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0045987	positive regulation of smooth muscle contraction
GO:0001516	prostaglandin biosynthetic process
GO:0042313	protein kinase C deactivation
GO:0007243	protein kinase cascade
GO:0008217	regulation of blood pressure
GO:0050880	regulation of blood vessel size
GO:0006885	regulation of pH
GO:0051930	regulation of sensory perception of pain
GO:0003100	regulation of systemic arterial blood pressure by endothelin
GO:0019229	regulation of vasoconstriction
GO:0007585	respiratory gaseous exchange
GO:0001666	response to hypoxia
GO:0043179	rhythmic excitation
GO:0019233	sensory perception of pain
GO:0001501	skeletal system development
GO:0042554	superoxide anion generation
GO:0042310	vasoconstriction
GO:0014826	vein smooth muscle contraction

Cellular Component

GO:0005737	cytoplasm
GO:0005576	extracellular region
GO:0005615	extracellular space

Molecular Function

GO:0005125	cytokine activity
GO:0031707	endothelin A receptor binding
GO:0031708	endothelin B receptor binding
GO:0005179	hormone activity
GO:0005515	protein binding
GO:0005102	receptor binding

endothelin 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function