eukaryotic translation initiation factor 2 alpha kinase 3

詳細情報を見る

同義遺伝子名

Perk, PEK, AI427929, Pancreatic eIF2-alpha kinase, PRKR-like endoplasmic reticulum kinase, Pek, perk, Eif2ak3

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:33

小脳:18.40

脳幹:63.60

脳梁:-

松果体:-

末梢神経:19.10

脊柱:-

網膜:-

目:68.40

動脈:-

静脈:-

リンパ節:-

末梢血:100.60

脾臓:-

胸腺:49.40

骨髄:25.60

脂肪:-

骨:37.60

皮膚:39.60

GeneChip

大脳:8.05

小脳:8.74

脳幹:-

脳梁:-

松果体:-

末梢神経:9.18

脊柱:8.33

網膜:8.65

目:7.79

動脈:-

静脈:8.84

リンパ節:9.61

末梢血:-

脾臓:9.48

胸腺:-

骨髄:9.30

脂肪:8.15

骨:9.03

皮膚:8.25

CAGE

大脳:3.12

小脳:-

脳幹:2.94

脳梁:-

松果体:-

末梢神経:-

脊柱:3.10

網膜:-

目:-

動脈:2.90

静脈:-

リンパ節:2.90

末梢血:-

脾臓:3.23

胸腺:3.71

骨髄:-

脂肪:-

骨:3.28

皮膚:2.99

RNA-seq

大脳:4.06

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:27.60

前立腺:61.80

卵巣:23

精巣:7.40

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:17.60

肝臓:18.10

肺:10

膀胱:-

腎臓:-

下垂体:12.90

甲状腺:112.50

副腎:-

膵臓:159.50

乳腺:29.40

唾液腺:54

GeneChip

子宮:8.70

胎盤:9.75

前立腺:10.45

卵巣:8.51

精巣:6.20

心臓:7.05

骨格筋:7.38

食道:-

胃:9.24

腸:9.35

結腸:-

肝臓:8.26

肺:8.89

膀胱:8.55

腎臓:8.70

下垂体:9.70

甲状腺:-

副腎:8.45

膵臓:10.47

乳腺:8.45

唾液腺:10.19

CAGE

子宮:2.98

胎盤:3.57

前立腺:4.10

卵巣:3.10

精巣:0.75

心臓:-

骨格筋:-

食道:-

胃:3.51

腸:3.50

結腸:3.55

肝臓:2.90

肺:3.36

膀胱:2.90

腎臓:-

下垂体:3.95

甲状腺:-

副腎:3.20

膵臓:5.24

乳腺:3.45

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.67

食道:-

胃:-

腸:-

結腸:-

肝臓:3.02

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_010121
Gene ID	13666
Unigene ID	Mm.247167
Probe set ID	1449278_at [Mouse430_2]
Ensembl ID	ENSMUSG00000031668

オーソログ対応遺伝子

ヒト[1]	NM_004836
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0006919	activation of caspase activity
GO:0070059	apoptosis in response to endoplasmic reticulum stress
GO:0030282	bone mineralization
GO:0019722	calcium-mediated signaling
GO:0002063	chondrocyte development
GO:0031018	endocrine pancreas development
GO:0007029	endoplasmic reticulum organization
GO:0030968	endoplasmic reticulum unfolded protein response
GO:0006983	ER overload response
GO:0045444	fat cell differentiation
GO:0048009	insulin-like growth factor receptor signaling pathway
GO:0007595	lactation
GO:0031642	negative regulation of myelination
GO:0017148	negative regulation of translation
GO:0032055	negative regulation of translation in response to stress
GO:0001503	ossification
GO:0031016	pancreas development
GO:0016310	phosphorylation
GO:0032092	positive regulation of protein binding
GO:0009967	positive regulation of signal transduction
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0051260	protein homooligomerization
GO:0019217	regulation of fatty acid metabolic process
GO:0006417	regulation of translation
GO:0034976	response to endoplasmic reticulum stress
GO:0006950	response to stress
GO:0006986	response to unfolded protein
GO:0001501	skeletal system development
GO:0032933	SREBP-mediated signaling pathway
GO:0006412	translation
GO:0006413	translational initiation
GO:0006926	virus-infected cell apoptosis

Cellular Component

GO:0005623	cell
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral to membrane
GO:0016020	membrane

Molecular Function

GO:0005524	ATP binding
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity
GO:0042802	identical protein binding
GO:0016301	kinase activity
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0019903	protein phosphatase binding
GO:0004674	protein serine/threonine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0003743	translation initiation factor activity

eukaryotic translation initiation factor 2 alpha kinase 3

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function