endoglin

詳細情報を見る

同義遺伝子名

CD105, Eng, Endoglin precursor, AI528660, Edg, Cell surface MJ7/18 antigen, endoglin, S-endoglin

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:36.50 小脳:18.40 脳幹:- 脳梁:- 松果体:- 末梢神経:76.40 脊柱:94.60 網膜:- 目:15.20 動脈:- 静脈:- リンパ節:21.60 末梢血:258.80 脾臓:131.70 胸腺:9.90 骨髄:115.40 脂肪:- 骨:300.60 皮膚:190
GeneChip 大脳:6 小脳:5.97 脳幹:- 脳梁:- 松果体:- 末梢神経:5.89 脊柱:6.05 網膜:5.58 目:6.87 動脈:- 静脈:7.21 リンパ節:7.40 末梢血:- 脾臓:7.54 胸腺:- 骨髄:6.44 脂肪:7.67 骨:6.85 皮膚:6.71
CAGE 大脳:3.44 小脳:- 脳幹:3.87 脳梁:- 松果体:- 末梢神経:- 脊柱:3.90 網膜:- 目:- 動脈:5.21 静脈:- リンパ節:4.84 末梢血:- 脾臓:4.57 胸腺:2.95 骨髄:- 脂肪:- 骨:3.87 皮膚:3.87
RNA-seq 大脳:6.13 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:218.10 胎盤:69 前立腺:- 卵巣:11.50 精巣:- 心臓:148.80 骨格筋:106.50 食道:- 胃:32.70 腸:- 結腸:123.40     肝臓:90.50        肺:281.20    膀胱:- 腎臓:129 下垂体:38.80 甲状腺:224.90 副腎:- 膵臓:28.10 乳腺:65.30 唾液腺:54
GeneChip 子宮:6.84 胎盤:6.78 前立腺:6.45 卵巣:7.23 精巣:5.72 心臓:9.05 骨格筋:7.86 食道:- 胃:6.58 腸:6.34 結腸:- 肝臓:7.59 肺:10.01 膀胱:7.04 腎臓:8 下垂体:6.71 甲状腺:- 副腎:7.98 膵臓:7.05 乳腺:7.53 唾液腺:6.95
CAGE 子宮:4.48 胎盤:4.70 前立腺:2.88 卵巣:4.59 精巣:0.45 心臓:- 骨格筋:- 食道:- 胃:4.20 腸:3.56 結腸:3.65     肝臓:5.03    肺:6.51 膀胱:4.30 腎臓:- 下垂体:3.97 甲状腺:- 副腎:5.00 膵臓:4.08 乳腺:4.24 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:5.53 食道:- 胃:- 腸:- 結腸:-     肝臓:14.92        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_001146350
Gene ID 13805
Unigene ID Mm.225297
Probe set ID 1432176_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000026814

オーソログ対応遺伝子

ヒト[4]  NM_000118, NM_001114753
ラット[4]  NM_000118, NM_001114753

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0048844  artery morphogenesis
GO:0007155  cell adhesion
GO:0060326  cell chemotaxis
GO:0016477  cell migration
GO:0003273  cell migration involved in endocardial cushion formation
GO:0048870  cell motility
GO:0022009  central nervous system vasculogenesis
GO:0070483  detection of hypoxia
GO:0022617  extracellular matrix disassembly
GO:0007507  heart development
GO:0001947  heart looping
GO:0030336  negative regulation of cell migration
GO:0001937  negative regulation of endothelial cell proliferation
GO:0051001  negative regulation of nitric-oxide synthase activity
GO:0060394  negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0031953  negative regulation of protein amino acid autophosphorylation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0001569  patterning of blood vessels
GO:0045766  positive regulation of angiogenesis
GO:0030513  positive regulation of BMP signaling pathway
GO:0010862  positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0003084  positive regulation of systemic arterial blood pressure
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0017015  regulation of transforming growth factor beta receptor signaling pathway
GO:0001666  response to hypoxia
GO:0048745  smooth muscle tissue development
GO:0007179  transforming growth factor beta receptor signaling pathway
GO:0001570  vasculogenesis
GO:0048845  venous blood vessel morphogenesis
GO:0042060  wound healing

Cellular Component

GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0009897  external side of plasma membrane
GO:0005615  extracellular space
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0005634  nucleus

Molecular Function

GO:0005534  galactose binding
GO:0005539  glycosaminoglycan binding
GO:0042803  protein homodimerization activity
GO:0050431  transforming growth factor beta binding
GO:0005024  transforming growth factor beta receptor activity
GO:0005072  transforming growth factor beta receptor, cytoplasmic mediator activity
GO:0034713  type I transforming growth factor beta receptor binding
GO:0005114  type II transforming growth factor beta receptor binding