coagulation factor II (thrombin) receptor-like 1

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同義遺伝子名

Par2, Coagulation factor II receptor-like 1, Gpcr11, Proteinase-activated receptor 2 precursor, G-protein coupled receptor 11, Thrombin receptor-like 1, coagulation factor II (thrombin) receptor-like 1, Gpr11, F2rl1, PAR-2, Protease-activated receptor-2

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:4.57 小脳:4.42 脳幹:- 脳梁:- 松果体:- 末梢神経:4.33 脊柱:4.60 網膜:4.61 目:6.03 動脈:- 静脈:5.38 リンパ節:6.20 末梢血:- 脾臓:5.52 胸腺:- 骨髄:4.58 脂肪:5.32 骨:4.64 皮膚:7.48
CAGE 大脳:0 小脳:- 脳幹:0.47 脳梁:- 松果体:- 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:1.32 静脈:- リンパ節:2.98 末梢血:- 脾臓:1.32 胸腺:1.69 骨髄:- 脂肪:- 骨:1.02 皮膚:3.98
RNA-seq 大脳:0.87 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:80.40 精巣:29.60 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:5.94 胎盤:7.78 前立腺:6.26 卵巣:4.79 精巣:4.59 心臓:4.93 骨格筋:4.73 食道:- 胃:8.37 腸:8.66 結腸:- 肝臓:4.60 肺:6.15 膀胱:5.51 腎臓:6.38 下垂体:5.46 甲状腺:- 副腎:4.59 膵臓:4.97 乳腺:5.26 唾液腺:5.34
CAGE 子宮:3.13 胎盤:2.85 前立腺:3.15 卵巣:1.19 精巣:0 心臓:- 骨格筋:- 食道:- 胃:4.13 腸:3.79 結腸:3.98     肝臓:0.26    肺:2.83 膀胱:2.35 腎臓:- 下垂体:2.22 甲状腺:- 副腎:0.26 膵臓:2.03 乳腺:1.84 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:0.76 食道:- 胃:- 腸:- 結腸:-     肝臓:0.36        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_007974
Gene ID 14063
Unigene ID Mm.161414
Probe set ID 1448931_at  [Mouse430_2]
Ensembl ID ENSMUSG00000021678

オーソログ対応遺伝子

ヒト[2]  NM_005242
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007596  blood coagulation
GO:0090195  chemokine secretion
GO:0051607  defense response to virus
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0050702  interleukin-1 beta secretion
GO:0050900  leukocyte migration
GO:0070661  leukocyte proliferation
GO:0090198  negative regulation of chemokine secretion
GO:0046329  negative regulation of JNK cascade
GO:0034140  negative regulation of toll-like receptor 3 signaling pathway
GO:0010804  negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0042119  neutrophil activation
GO:0030836  positive regulation of actin filament depolymerization
GO:0030335  positive regulation of cell migration
GO:0050921  positive regulation of chemotaxis
GO:0002741  positive regulation of cytokine secretion during immune response
GO:0043311  positive regulation of eosinophil degranulation
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0003104  positive regulation of glomerular filtration
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0046330  positive regulation of JNK cascade
GO:0002690  positive regulation of leukocyte chemotaxis
GO:0070963  positive regulation of neutrophil mediated killing of gram-negative bacterium
GO:0060100  positive regulation of phagocytosis, engulfment
GO:0014068  positive regulation of phosphoinositide 3-kinase cascade
GO:0050927  positive regulation of positive chemotaxis
GO:0031274  positive regulation of pseudopodium assembly
GO:0035025  positive regulation of Rho protein signal transduction
GO:0032930  positive regulation of superoxide release
GO:0034137  positive regulation of toll-like receptor 2 signaling pathway
GO:0034141  positive regulation of toll-like receptor 3 signaling pathway
GO:0034145  positive regulation of toll-like receptor 4 signaling pathway
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045909  positive regulation of vasodilation
GO:0030193  regulation of blood coagulation
GO:0043122  regulation of I-kappaB kinase/NF-kappaB cascade
GO:0046328  regulation of JNK cascade
GO:0007165  signal transduction
GO:0002286  T cell activation during immune response
GO:0070493  thrombin receptor signaling pathway

Cellular Component

GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0005886  plasma membrane
GO:0031143  pseudopodium

Molecular Function

GO:0001965  G-protein alpha-subunit binding
GO:0031681  G-protein beta-subunit binding
GO:0004930  G-protein coupled receptor activity
GO:0032795  heterotrimeric G-protein binding
GO:0004871  signal transducer activity
GO:0015057  thrombin receptor activity