PTK2 protein tyrosine kinase 2

同義遺伝子名

mKIAA4203, pp125FAK, Fak, Ptk2, Fadk, FRNK, PTK2 protein tyrosine kinase 2, FADK 1, Fak1, Focal adhesion kinase 1, FAK, KIAA4203

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:156.30

小脳:202.60

脳幹:127.10

脳梁:-

松果体:-

末梢神経:76.40

脊柱:236.40

網膜:96.40

目:121.60

動脈:168.80

静脈:-

リンパ節:-

末梢血:14.40

脾臓:39.50

胸腺:88.90

骨髄:-

脂肪:-

骨:100.20

皮膚:63.30

GeneChip

大脳:9.30

小脳:8.47

脳幹:-

脳梁:-

松果体:-

末梢神経:8.09

脊柱:8.65

網膜:8.32

目:8.14

動脈:-

静脈:9.74

リンパ節:7.80

末梢血:-

脾臓:7.59

胸腺:-

骨髄:6.57

脂肪:8.24

骨:7.11

皮膚:7.82

CAGE

大脳:3.75

小脳:-

脳幹:3.36

脳梁:-

松果体:-

末梢神経:-

脊柱:3.35

網膜:-

目:-

動脈:3.43

静脈:-

リンパ節:3.10

末梢血:-

脾臓:2.51

胸腺:1.85

骨髄:-

脂肪:-

骨:2.45

皮膚:3.17

RNA-seq

大脳:6.22

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:174.50

胎盤:82.80

前立腺:-

卵巣:160.90

精巣:110.80

心臓:111.60

骨格筋:-

食道:-

胃:-

腸:-

結腸:52.90

肝臓:-

肺:170.70

膀胱:66.20

腎臓:40.30

下垂体:-

甲状腺:112.50

副腎:-

膵臓:18.80

乳腺:94.70

唾液腺:-

GeneChip

子宮:8.98

胎盤:9.50

前立腺:8.69

卵巣:9.02

精巣:8.94

心臓:7.98

骨格筋:8.29

食道:-

胃:8.57

腸:8.69

結腸:-

肝臓:7.91

肺:9.79

膀胱:8.81

腎臓:8.23

下垂体:9.22

甲状腺:-

副腎:8.30

膵臓:8.31

乳腺:8.57

唾液腺:8.69

CAGE

子宮:3.86

胎盤:3.95

前立腺:3.34

卵巣:3.64

精巣:3.00

心臓:-

骨格筋:-

食道:-

胃:2.36

腸:3.37

結腸:3.26

肝臓:3.31

肺:4.15

膀胱:3.07

腎臓:-

下垂体:3.42

甲状腺:-

副腎:3.33

膵臓:3.32

乳腺:3.87

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:2.91

食道:-

胃:-

腸:-

結腸:-

肝臓:2.56

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_007982
Gene ID	14083
Unigene ID	Mm.254494
Probe set ID	1423059_at [Mouse430_2]
Ensembl ID	ENSMUSG00000022607

オーソログ対応遺伝子

ヒト[4]	NM_001199649, NM_005607, NM_153831
ラット [0]

染色体

15D3 [73,035,535 - 73,253,621]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR019749	Band 4.1 domain
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0001525	angiogenesis
GO:0001568	blood vessel development
GO:0030644	cellular chloride ion homeostasis
GO:0006928	cellular component movement
GO:0021955	central nervous system neuron axonogenesis
GO:0043542	endothelial cell migration
GO:0048013	ephrin receptor signaling pathway
GO:0040023	establishment of nucleus localization
GO:0030198	extracellular matrix organization
GO:0060396	growth hormone receptor signaling pathway
GO:0007229	integrin-mediated signaling pathway
GO:0007254	JNK cascade
GO:0000165	MAPKKK cascade
GO:0000226	microtubule cytoskeleton organization
GO:0007275	multicellular organismal development
GO:0043066	negative regulation of apoptosis
GO:0050771	negative regulation of axonogenesis
GO:0030336	negative regulation of cell migration
GO:0022408	negative regulation of cell-cell adhesion
GO:0046621	negative regulation of organ growth
GO:0051964	negative regulation of synaptogenesis
GO:0001764	neuron migration
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0016310	phosphorylation
GO:0045785	positive regulation of cell adhesion
GO:0030307	positive regulation of cell growth
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0060252	positive regulation of glial cell proliferation
GO:0050766	positive regulation of phagocytosis
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0045860	positive regulation of protein kinase activity
GO:0051897	positive regulation of protein kinase B signaling cascade
GO:0014911	positive regulation of smooth muscle cell migration
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0050806	positive regulation of synaptic transmission
GO:0045909	positive regulation of vasodilation
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0033628	regulation of cell adhesion mediated by integrin
GO:0042127	regulation of cell proliferation
GO:0008360	regulation of cell shape
GO:0045667	regulation of osteoblast differentiation
GO:0007172	signal complex assembly
GO:0001570	vasculogenesis

Cellular Component

GO:0016324	apical plasma membrane
GO:0016323	basolateral plasma membrane
GO:0030054	cell junction
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005829	cytosol
GO:0005925	focal adhesion
GO:0014704	intercalated disc
GO:0030027	lamellipodium
GO:0016020	membrane
GO:0016604	nuclear body
GO:0005730	nucleolus
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0042383	sarcolemma

Molecular Function

GO:0003779	actin binding
GO:0005524	ATP binding
GO:0005178	integrin binding
GO:0008432	JUN kinase binding
GO:0016301	kinase activity
GO:0004715	non-membrane spanning protein tyrosine kinase activity
GO:0000166	nucleotide binding
GO:0043548	phosphoinositide 3-kinase binding
GO:0005515	protein binding
GO:0032403	protein complex binding
GO:0004672	protein kinase activity
GO:0019901	protein kinase binding
GO:0004713	protein tyrosine kinase activity
GO:0042169	SH2 domain binding
GO:0004871	signal transducer activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

PTK2 protein tyrosine kinase 2

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function