fibroblast growth factor receptor 1

詳細情報を見る

同義遺伝子名

AW208770, Flg, bFGF-R, Flt-2, Fgfr-1, fibroblast growth factor receptor 1, FGFR-1, Fgfr1, CD331 antigen, FLG, MFR

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:7.77 小脳:8.76 脳幹:- 脳梁:- 松果体:- 末梢神経:9.23 脊柱:8.89 網膜:6.52 目:7.15 動脈:- 静脈:8.73 リンパ節:6.51 末梢血:- 脾臓:6.44 胸腺:- 骨髄:5.21 脂肪:8.64 骨:7.60 皮膚:8.53
CAGE 大脳:4.43 小脳:- 脳幹:4.09 脳梁:- 松果体:- 末梢神経:- 脊柱:4.24 網膜:- 目:- 動脈:4.61 静脈:- リンパ節:2.62 末梢血:- 脾臓:2.18 胸腺:1.85 骨髄:- 脂肪:- 骨:3.77 皮膚:4.67
RNA-seq 大脳:13.33 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST nodata
GeneChip 子宮:7.99 胎盤:10.59 前立腺:8.11 卵巣:8.12 精巣:6.05 心臓:7.27 骨格筋:8.74 食道:- 胃:7.19 腸:6.62 結腸:- 肝臓:5.75 肺:7.96 膀胱:8.74 腎臓:7.53 下垂体:7.77 甲状腺:- 副腎:9.17 膵臓:7.95 乳腺:8.60 唾液腺:7.78
CAGE 子宮:3.55 胎盤:5.68 前立腺:3.37 卵巣:3.78 精巣:1.34 心臓:- 骨格筋:- 食道:- 胃:3.09 腸:2.52 結腸:2.42     肝臓:1.22    肺:3.74 膀胱:4.47 腎臓:- 下垂体:3.57 甲状腺:- 副腎:4.32 膵臓:4.37 乳腺:3.67 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:7.75 食道:- 胃:- 腸:- 結腸:-     肝臓:3.29        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_010206
Gene ID 14182
Unigene ID -
Probe set ID 1424050_s_at  [Mouse430_2]
Ensembl ID ENSMUSG00000031565

オーソログ対応遺伝子

ヒト[7]  NM_001174063, NM_001174064, NM_001174065, NM_001174066, NM_001174067, NM_015850, NM_023105, NM_023106, NM_023110
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0060117  auditory receptor cell development
GO:0048514  blood vessel morphogenesis
GO:0007420  brain development
GO:0060445  branching involved in salivary gland morphogenesis
GO:0048469  cell maturation
GO:0021954  central nervous system neuron development
GO:0002062  chondrocyte differentiation
GO:0030326  embryonic limb morphogenesis
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0048699  generation of neurons
GO:0001701  in utero embryonic development
GO:0001759  induction of an organ
GO:0042472  inner ear morphogenesis
GO:0030324  lung development
GO:0060484  lung-associated mesenchyme development
GO:0048762  mesenchymal cell differentiation
GO:0030901  midbrain development
GO:0042474  middle ear morphogenesis
GO:0021837  motogenic signaling involved in postnatal olfactory bulb interneuron migration
GO:0010629  negative regulation of gene expression
GO:0045668  negative regulation of osteoblast differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0021847  neuroblast division in the ventricular zone
GO:0031175  neuron projection development
GO:0021769  orbitofrontal cortex development
GO:0042473  outer ear morphogenesis
GO:0048339  paraxial mesoderm development
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0016310  phosphorylation
GO:0060045  positive regulation of cardiac muscle cell proliferation
GO:0045787  positive regulation of cell cycle
GO:0008284  positive regulation of cell proliferation
GO:0043406  positive regulation of MAP kinase activity
GO:0043410  positive regulation of MAPKKK cascade
GO:0090080  positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0045666  positive regulation of neuron differentiation
GO:0010976  positive regulation of neuron projection development
GO:0010863  positive regulation of phospholipase C activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0060665  regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
GO:0042127  regulation of cell proliferation
GO:0010468  regulation of gene expression
GO:0048378  regulation of lateral mesodermal cell fate specification
GO:0051930  regulation of sensory perception of pain
GO:0007435  salivary gland morphogenesis
GO:0007605  sensory perception of sound
GO:0019827  stem cell maintenance
GO:0001657  ureteric bud development
GO:0060979  vasculogenesis involved in coronary vascular morphogenesis

Cellular Component

GO:0005737  cytoplasm
GO:0031410  cytoplasmic vesicle
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0050839  cell adhesion molecule binding
GO:0017134  fibroblast growth factor binding
GO:0005007  fibroblast growth factor receptor activity
GO:0001948  glycoprotein binding
GO:0008201  heparin binding
GO:0042802  identical protein binding
GO:0016301  kinase activity
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0042803  protein homodimerization activity
GO:0004672  protein kinase activity
GO:0004713  protein tyrosine kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups
GO:0004714  transmembrane receptor protein tyrosine kinase activity