growth hormone receptor

詳細情報を見る

同義遺伝子名

GHBP, AA986417, Growth hormone receptor precursor, GHR/BP, growth hormone receptor, Ghr, Somatotropin receptor, GH receptor

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:38.20 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:7.34 小脳:7.49 脳幹:- 脳梁:- 松果体:- 末梢神経:9.32 脊柱:6.96 網膜:6.97 目:9.32 動脈:- 静脈:11.93 リンパ節:9.38 末梢血:- 脾臓:6.37 胸腺:- 骨髄:6.67 脂肪:12.44 骨:8.59 皮膚:10.46
CAGE 大脳:2.08 小脳:- 脳幹:2.68 脳梁:- 松果体:- 末梢神経:- 脊柱:2.96 網膜:- 目:- 動脈:5.75 静脈:- リンパ節:2.90 末梢血:- 脾臓:1.60 胸腺:2.29 骨髄:- 脂肪:- 骨:3.32 皮膚:4.94
RNA-seq 大脳:4.24 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:7.40 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:9.42 胎盤:10.32 前立腺:9.95 卵巣:11.01 精巣:4.90 心臓:10.99 骨格筋:11.53 食道:- 胃:10 腸:8.52 結腸:- 肝臓:12.57 肺:10.47 膀胱:9.75 腎臓:12.90 下垂体:7.17 甲状腺:- 副腎:10.76 膵臓:9.97 乳腺:11.85 唾液腺:10.37
CAGE 子宮:3.56 胎盤:3.59 前立腺:2.45 卵巣:4.52 精巣:1.60 心臓:- 骨格筋:- 食道:- 胃:4.20 腸:2.83 結腸:3.23     肝臓:6.26    肺:4.45 膀胱:4.14 腎臓:- 下垂体:2.53 甲状腺:- 副腎:3.96 膵臓:5.28 乳腺:4.97 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:12.60 食道:- 胃:- 腸:- 結腸:-     肝臓:44.44        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_010284
Gene ID 14600
Unigene ID Mm.39860
Probe set ID 1417962_s_at  [Mouse430_2]
Ensembl ID ENSMUSG00000055737

オーソログ対応遺伝子

ヒト[2]  NM_000163, NM_001242399, NM_001242400, NM_001242401, NM_001242402, NM_001242403, NM_001242404, NM_001242405, NM_001242406, NM_001242460, NM_001242461, NM_001242462
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006103  2-oxoglutarate metabolic process
GO:0042977  activation of JAK2 kinase activity
GO:0042976  activation of Janus kinase activity
GO:0000187  activation of MAPK activity
GO:0000255  allantoin metabolic process
GO:0032870  cellular response to hormone stimulus
GO:0006101  citrate metabolic process
GO:0006600  creatine metabolic process
GO:0046449  creatinine metabolic process
GO:0019221  cytokine-mediated signaling pathway
GO:0006897  endocytosis
GO:0006631  fatty acid metabolic process
GO:0060396  growth hormone receptor signaling pathway
GO:0009755  hormone-mediated signaling pathway
GO:0048009  insulin-like growth factor receptor signaling pathway
GO:0006549  isoleucine metabolic process
GO:0007259  JAK-STAT cascade
GO:0044236  multicellular organismal metabolic process
GO:0006107  oxaloacetate metabolic process
GO:0046427  positive regulation of JAK-STAT cascade
GO:0040018  positive regulation of multicellular organism growth
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0040014  regulation of multicellular organism growth
GO:0032355  response to estradiol stimulus
GO:0006105  succinate metabolic process
GO:0019530  taurine metabolic process
GO:0006573  valine metabolic process

Cellular Component

GO:0043025  cell soma
GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0019898  extrinsic to membrane
GO:0070195  growth hormone receptor complex
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0005739  mitochondrion
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0043235  receptor complex

Molecular Function

GO:0004896  cytokine receptor activity
GO:0019838  growth factor binding
GO:0004903  growth hormone receptor activity
GO:0017046  peptide hormone binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0019901  protein kinase binding
GO:0019903  protein phosphatase binding
GO:0042169  SH2 domain binding