gap junction protein, alpha 1

 詳細情報を見る

同義遺伝子名

Gja1, connexin 43, gap junction membrane channel protein alpha 1, alpha 1 connexin, Npm1, Cx43, Cnx43, Gap junction 43 kDa heart protein, Cxn-43, connexin43, Gap junction alpha-1 protein, Cx43alpha1, Gja-1, Connexin-43, AU042049, AW546267

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST nodata
GeneChip 大脳:11.89 小脳:12.06 脳幹:- 脳梁:- 松果体:- 末梢神経:9.14 脊柱:12.41 網膜:9.91 目:12.57 動脈:- 静脈:12.95 リンパ節:7.97 末梢血:- 脾臓:10.35 胸腺:- 骨髄:9.51 脂肪:12.12 骨:12.34 皮膚:12.55
CAGE 大脳:5.23 小脳:- 脳幹:5.52 脳梁:- 松果体:- 末梢神経:- 脊柱:5.77 網膜:- 目:- 動脈:4.95 静脈:- リンパ節:2.77 末梢血:- 脾臓:3.74 胸腺:2.22 骨髄:- 脂肪:- 骨:3.75 皮膚:5.68
RNA-seq 大脳:9.09 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST nodata
GeneChip 子宮:11.06 胎盤:12.12 前立腺:7.12 卵巣:13.45 精巣:9.12 心臓:12.89 骨格筋:8.75 食道:- 胃:11.29 腸:9.40 結腸:- 肝臓:6.65 肺:10.62 膀胱:9.49 腎臓:7.41 下垂体:9.05 甲状腺:- 副腎:11.42 膵臓:8.81 乳腺:10.80 唾液腺:9.73
CAGE 子宮:4.82 胎盤:6.06 前立腺:2.06 卵巣:6.61 精巣:3.16 心臓:- 骨格筋:- 食道:- 胃:4.94 腸:2.93 結腸:3.33     肝臓:2.41    肺:4.04 膀胱:3.01 腎臓:- 下垂体:3.42 甲状腺:- 副腎:3.98 膵臓:2.33 乳腺:3.49 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.89 食道:- 胃:- 腸:- 結腸:-     肝臓:2.90        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_010288
Gene ID 14609
Unigene ID -
Probe set ID 1437992_x_at  [Mouse430_2]
Ensembl ID ENSMUSG00000050953

オーソログ対応遺伝子

ヒト[1]  NM_000165
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

IPR000500  Connexins
IPR002261  Gap junction alpha-1 protein (Cx43)

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0007512  adult heart development
GO:0006915  apoptosis
GO:0015867  ATP transport
GO:0003294  atrial ventricular junction remodeling
GO:0048514  blood vessel morphogenesis
GO:0007154  cell communication
GO:0010643  cell communication by chemical coupling
GO:0010644  cell communication by electrical coupling
GO:0045216  cell-cell junction organization
GO:0007267  cell-cell signaling
GO:0002544  chronic inflammatory response
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0042733  embryonic digit morphogenesis
GO:0035050  embryonic heart tube development
GO:0003347  epicardial cell to mesenchymal cell transition
GO:0002070  epithelial cell maturation
GO:0090162  establishment of epithelial cell polarity
GO:0007507  heart development
GO:0001947  heart looping
GO:0001701  in utero embryonic development
GO:0002088  lens development in camera-type eye
GO:0060156  milk ejection
GO:0060044  negative regulation of cardiac muscle cell proliferation
GO:0008285  negative regulation of cell proliferation
GO:0010629  negative regulation of gene expression
GO:0001764  neuron migration
GO:0048812  neuron projection morphogenesis
GO:0001649  osteoblast differentiation
GO:0010652  positive regulation of cell communication by chemical coupling
GO:0010628  positive regulation of gene expression
GO:0003104  positive regulation of glomerular filtration
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0045732  positive regulation of protein catabolic process
GO:0045844  positive regulation of striated muscle tissue development
GO:0045907  positive regulation of vasoconstriction
GO:0045909  positive regulation of vasodilation
GO:0051259  protein oligomerization
GO:0060371  regulation of atrial cardiomyocyte membrane depolarization
GO:0060312  regulation of blood vessel remodeling
GO:0030500  regulation of bone mineralization
GO:0046850  regulation of bone remodeling
GO:0051924  regulation of calcium ion transport
GO:0008016  regulation of heart contraction
GO:0060373  regulation of ventricular cardiomyocyte membrane depolarization
GO:0060307  regulation of ventricular cardiomyocyte membrane repolarization
GO:0009268  response to pH
GO:0007165  signal transduction
GO:0043403  skeletal muscle tissue regeneration
GO:0055085  transmembrane transport
GO:0010232  vascular transport

Cellular Component

GO:0016324  apical plasma membrane
GO:0030054  cell junction
GO:0005911  cell-cell junction
GO:0005922  connexon complex
GO:0043292  contractile fiber
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005769  early endosome
GO:0005768  endosome
GO:0005916  fascia adherens
GO:0005921  gap junction
GO:0005794  Golgi apparatus
GO:0016021  integral to membrane
GO:0014704  intercalated disc
GO:0005882  intermediate filament
GO:0005770  late endosome
GO:0016328  lateral plasma membrane
GO:0005764  lysosome
GO:0016020  membrane
GO:0045121  membrane raft
GO:0005741  mitochondrial outer membrane
GO:0005771  multivesicular body
GO:0005886  plasma membrane

Molecular Function

GO:0048487  beta-tubulin binding
GO:0071253  connexin binding
GO:0005243  gap junction channel activity
GO:0030165  PDZ domain binding
GO:0005515  protein binding
GO:0019904  protein domain specific binding
GO:0005102  receptor binding
GO:0017124  SH3 domain binding
GO:0004871  signal transducer activity
GO:0022857  transmembrane transporter activity