protein tyrosine phosphatase, non-receptor type 6

詳細情報を見る

同義遺伝子名

PTPTY-42, motheaten, Hcph, Ptpn6, protein tyrosine phosphatase, non-receptor type 6, SH-PTP1, Hematopoietic cell protein-tyrosine phosphatase, me, PTP-1C, Tyrosine-protein phosphatase non-receptor type 6, Ptp1C, Hcp, Protein-tyrosine phosphatase 1C, 70Z-SHP, hcp

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:13.90 小脳:36.80 脳幹:- 脳梁:- 松果体:- 末梢神経:19.10 脊柱:- 網膜:- 目:- 動脈:337.60 静脈:- リンパ節:32.40 末梢血:143.80 脾臓:118.50 胸腺:247 骨髄:192.30 脂肪:212.70 骨:175.30 皮膚:55.40
GeneChip 大脳:5.66 小脳:5.19 脳幹:- 脳梁:- 松果体:- 末梢神経:5.69 脊柱:5.80 網膜:5.99 目:6.63 動脈:- 静脈:6.65 リンパ節:12.26 末梢血:- 脾臓:12.56 胸腺:- 骨髄:10.68 脂肪:6.90 骨:10.57 皮膚:7.88
CAGE 大脳:0.72 小脳:- 脳幹:1.15 脳梁:- 松果体:- 末梢神経:- 脊柱:1.23 網膜:- 目:- 動脈:2.27 静脈:- リンパ節:5.22 末梢血:- 脾臓:4.85 胸腺:4.52 骨髄:- 脂肪:- 骨:4.65 皮膚:2.78
RNA-seq 大脳:1.70 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:96.70 前立腺:- 卵巣:46 精巣:7.40 心臓:18.60 骨格筋:- 食道:- 胃:32.70 腸:- 結腸:52.90     肝臓:18.10        肺:30.10    膀胱:132.40 腎臓:24.20 下垂体:25.80 甲状腺:- 副腎:- 膵臓:75.10 乳腺:19.60 唾液腺:-
GeneChip 子宮:7.88 胎盤:7.55 前立腺:8.08 卵巣:6.94 精巣:5.81 心臓:6.02 骨格筋:6.77 食道:- 胃:7.96 腸:8.09 結腸:- 肝臓:8.35 肺:8.56 膀胱:6.77 腎臓:7.75 下垂体:8.26 甲状腺:- 副腎:6.23 膵臓:7.34 乳腺:8.25 唾液腺:7.60
CAGE 子宮:2.44 胎盤:2.08 前立腺:2.11 卵巣:2.04 精巣:0.45 心臓:- 骨格筋:- 食道:- 胃:2.36 腸:2.33 結腸:3.07     肝臓:2.87    肺:3.74 膀胱:2.29 腎臓:- 下垂体:2.81 甲状腺:- 副腎:2.75 膵臓:2.97 乳腺:3.00 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.09 食道:- 胃:- 腸:- 結腸:-     肝臓:3.75        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_001077705
Gene ID 15170
Unigene ID Mm.271799
Probe set ID 1460188_at  [Mouse430_2]
Ensembl ID ENSMUSG00000004266

オーソログ対応遺伝子

ヒト[3]  NM_002831, NM_080548, NM_080549
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

56406
221571
363947
664185
1184950
1270804
1373816
1385421
1427910
1732748
1756226
1932742
2196000
2783574
2884254
3551623
3873348
3891855
6334306
6350031
6361123
6380298
6971254
7536621
7600299
7768898
7804149
7840851
7923924
7943179
8070815
8093859
8118868
8245788
8324828
8348149
8617496
8632004
8636158
8666788
8673130
8781712
8822276
8863726
8875997
8943354
8962111
9034146
9064328
9064344
9070220
9184911
9216734
9254656
9263478
9300728
9358756
9371744
9422771
9445485
9505936
9573011
9586639
9587708
9593582
9636682
9712903
9740804
9808051
9824165
9890995
10201897
10229823
10229828
10349636
10352248
10358768
10363996
10393854
10419485
10435725
10477552
10477564
10495129
10585470
10590266
10611342
10698306
10903732
10922068
11042159
11067945
11076861
11145649
11157073
11159516
11217851
11266449
11283158
11389549
11551923
11668176
11745335
11745639
11826756
11908943
11908944
11970996
12097380
12176909
12220225
12466851
12477932
12511594
12612075
12644021
12645942
12742656
12893283
14500659
14662855
14967925
14987753
14988381
15197735
15240733
15339845
15364920
15456853
15489334
15634925
15661890
15701718
15723811
15728495
15905501
16141072
16141073
16237056
16265671
16326706
16487932
16492738
16505059
16528752
16565987
16569683
16617349
16731527
16782884
16860389
17003515
17057094
17182570
17239631
17600736
17934470
18003716
18024433
18028878
18258420
18391954
18424711
18441283
18617527
18719282
18799693
18806225
18832698
18952289
18952567
18981103
18987138
19120489
19171907
19201834
19380785
19419305
19647226
19727691
19789387
19875169
20042576
20117097
20145200
20190757
20368344
20400923
20421975
20526344
20696858
20858858
20952680
21044800
21160041
21267068
21356343
21357539
21364532
21376641
21422245
21423172
21435452
21559430
21664461
21677750
21683628
21900501
21952243
22077594
22337713
22415018
22438258
22491248
22496641
22499584
22509389
22539788
22553146
22555432
22698917
22798664
22798667
22826316
22952938
23001144
23341629
23390550
23427253
23479228
23509158
23509253
23521885
23531619
23640895
23708968
23766558
23793062
23797092
23840825
23896411
23904162
24029230
24327268
24360797

遺伝子オントロジー  (GO ID)

Biological Process

GO:0050853  B cell receptor signaling pathway
GO:0030154  cell differentiation
GO:0008283  cell proliferation
GO:0019221  cytokine-mediated signaling pathway
GO:0016311  dephosphorylation
GO:0042267  natural killer cell mediated cytotoxicity
GO:0002924  negative regulation of humoral immune response mediated by circulating immunoglobulin
GO:0043407  negative regulation of MAP kinase activity
GO:0043409  negative regulation of MAPKKK cascade
GO:0050732  negative regulation of peptidyl-tyrosine phosphorylation
GO:0042130  negative regulation of T cell proliferation
GO:0050860  negative regulation of T cell receptor signaling pathway
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0008284  positive regulation of cell proliferation
GO:0014068  positive regulation of phosphoinositide 3-kinase cascade
GO:0006470  protein amino acid dephosphorylation
GO:0045577  regulation of B cell differentiation
GO:0070372  regulation of ERK1 and ERK2 cascade

Cellular Component

GO:0042105  alpha-beta T cell receptor complex
GO:0005737  cytoplasm
GO:0005634  nucleus

Molecular Function

GO:0016787  hydrolase activity
GO:0046703  natural killer cell lectin-like receptor binding
GO:0016791  phosphatase activity
GO:0004721  phosphoprotein phosphatase activity
GO:0001784  phosphotyrosine binding
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0004725  protein tyrosine phosphatase activity
GO:0042169  SH2 domain binding
GO:0017124  SH3 domain binding
GO:0005001  transmembrane receptor protein tyrosine phosphatase activity