homeodomain interacting protein kinase 1

 詳細情報を見る

同義遺伝子名

Nuclear body-associated kinase 2, 1110062K04Rik, Myak, Nbak2, Kiaa0630, Hipk1, homeodomain interacting protein kinase 1, Protein kinase Myak, Homeodomain-interacting protein kinase 1

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST nodata
GeneChip 大脳:5.43 小脳:6.19 脳幹:- 脳梁:- 松果体:- 末梢神経:5.16 脊柱:5.60 網膜:5.54 目:5.65 動脈:- 静脈:5.57 リンパ節:5.73 末梢血:- 脾臓:6.35 胸腺:- 骨髄:7.59 脂肪:6.13 骨:6.42 皮膚:5.14
CAGE 大脳:4.19 小脳:- 脳幹:3.94 脳梁:- 松果体:- 末梢神経:- 脊柱:3.99 網膜:- 目:- 動脈:4.38 静脈:- リンパ節:4.42 末梢血:- 脾臓:5.19 胸腺:4.61 骨髄:- 脂肪:- 骨:5.28 皮膚:4.33
RNA-seq 大脳:4.54 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST nodata
GeneChip 子宮:5.96 胎盤:5.63 前立腺:5.39 卵巣:5.59 精巣:10.12 心臓:6.04 骨格筋:5.59 食道:- 胃:5.71 腸:5.86 結腸:- 肝臓:5.96 肺:5.84 膀胱:5.99 腎臓:6.38 下垂体:5.15 甲状腺:- 副腎:5.43 膵臓:5.96 乳腺:5.68 唾液腺:5.52
CAGE 子宮:4.32 胎盤:3.85 前立腺:3.78 卵巣:4.24 精巣:5.67 心臓:- 骨格筋:- 食道:- 胃:3.62 腸:3.51 結腸:3.85     肝臓:3.80    肺:4.59 膀胱:4.22 腎臓:- 下垂体:3.77 甲状腺:- 副腎:4.13 膵臓:3.61 乳腺:4.51 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.01 食道:- 胃:- 腸:- 結腸:-     肝臓:3.31        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_010432
Gene ID 15257
Unigene ID -
Probe set ID 1425988_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000008730

オーソログ対応遺伝子

ヒト[10]  NM_152696, NM_181358, NM_198268, NM_198269
ラット[1]  NM_001100986, NM_181358, NM_198268, NM_198269

染色体

-

遺伝子ファミリー (Interpro ID)

IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

8889548
9748262
10349636
10694743
10922068
11034606
11042159
11076861
11125038
11217851
12466851
12477932
12529400
12693553
12702766
14610273
15592455
16141072
16141073
16537918
16917507
16940173
17114649
18219322
18799693
20579985
21267068
22095214
22173032
22545114
23565059

遺伝子オントロジー  (GO ID)

Biological Process

GO:0009952  anterior/posterior pattern formation
GO:0042771  DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
GO:0048596  embryonic camera-type eye morphogenesis
GO:0060059  embryonic retina morphogenesis in camera-type eye
GO:0060235  lens induction in camera-type eye
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0030182  neuron differentiation
GO:0016310  phosphorylation
GO:0008284  positive regulation of cell proliferation
GO:0043388  positive regulation of DNA binding
GO:0006468  protein amino acid phosphorylation
GO:0016926  protein desumoylation
GO:0006355  regulation of transcription, DNA-dependent
GO:0010803  regulation of tumor necrosis factor-mediated signaling pathway
GO:0010842  retina layer formation
GO:0007224  smoothened signaling pathway
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0016607  nuclear speck
GO:0005634  nucleus
GO:0016605  PML body

Molecular Function

GO:0005524  ATP binding
GO:0003677  DNA binding
GO:0042802  identical protein binding
GO:0016301  kinase activity
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0004674  protein serine/threonine kinase activity
GO:0003714  transcription corepressor activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups