forkhead box A2

 詳細情報を見る

同義遺伝子名

Hepatocyte nuclear factor 3-beta, HNF3beta, HNF-3B, forkhead box A2, Foxa2, Hnf3b, Tcf3b, Forkhead box protein A2, HNF3-beta, Hnf-3b, Tcf-3b

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:8.70 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:38.20 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:79 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:15.80
GeneChip 大脳:4.56 小脳:4.68 脳幹:- 脳梁:- 松果体:- 末梢神経:4.32 脊柱:4.57 網膜:4.66 目:5.06 動脈:- 静脈:4.57 リンパ節:4.56 末梢血:- 脾臓:4.75 胸腺:- 骨髄:4.50 脂肪:4.76 骨:4.59 皮膚:4.58
CAGE 大脳:0 小脳:- 脳幹:0.36 脳梁:- 松果体:- 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0 静脈:- リンパ節:0 末梢血:- 脾臓:0 胸腺:0 骨髄:- 脂肪:- 骨:0.63 皮膚:0
RNA-seq 大脳:0.75 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:41.40 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:17.60     肝臓:45.30        肺:40.20    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:28.10 乳腺:9.80 唾液腺:-
GeneChip 子宮:5.97 胎盤:6.55 前立腺:4.51 卵巣:5.53 精巣:4.92 心臓:5.10 骨格筋:5.09 食道:- 胃:7.77 腸:7.36 結腸:- 肝臓:8 肺:8.35 膀胱:4.42 腎臓:4.66 下垂体:5.01 甲状腺:- 副腎:4.38 膵臓:9.25 乳腺:4.45 唾液腺:5
CAGE 子宮:2.22 胎盤:1.56 前立腺:0 卵巣:1.19 精巣:0 心臓:- 骨格筋:- 食道:- 胃:4.01 腸:1.14 結腸:1.34     肝臓:3.57    肺:3.59 膀胱:0 腎臓:- 下垂体:0 甲状腺:- 副腎:0.14 膵臓:3.77 乳腺:0 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:0.76 食道:- 胃:- 腸:- 結腸:-     肝臓:3.33        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_010446
Gene ID 15376
Unigene ID Mm.938
Probe set ID 1422833_at  [Mouse430_2]
Ensembl ID ENSMUSG00000037025

オーソログ対応遺伝子

ヒト[4]  NM_021784, NM_153675
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

IPR001766  Transcription factor, fork head
IPR011991  Winged helix repressor DNA-binding

Link to Pubmed  (Pubmed ID)

1363228
1612587
1672118
7606937
7657163
7671817
7689224
7700351
7720556
7768172
7776982
7916661
7925656
7958446
7958910
8001822
8034310
8069909
8069910
8187630
8248124
8287471
8306889
8375339
8543149
8565076
8565836
8610012
8625829
8674409
8756299
8787761
8813084
8837770
8951074
8978605
9032290
9078438
9118802
9119385
9136932
9136933
9152011
9216996
9226455
9232602
9247260
9260895
9262482
9315659
9334279
9371744
9415428
9431803
9441664
9441679
9466889
9486531
9490412
9493826
9500550
9520484
9550720
9550729
9585504
9598342
9636069
9655799
9671576
9712518
9731531
9731532
9739106
9739117
9774514
9790191
9799237
9811571
9811865
9825865
9851841
9876179
9895322
10049364
10079226
10191046
10208738
10217145
10328927
10349636
10373301
10385121
10421635
10423398
10430909
10433919
10452853
10471502
10477299
10479450
10479457
10498685
10499586
10512182
10512192
10516314
10518210
10545241
10559496
10600708
10642791
10672453
10688202
10725236
10727859
10772805
10804177
10804184
10809672
10818213
10859308
10866673
10887078
10899756
10964471
10985852
11002334
11017084
11027604
11042159
11071781
11076756
11076861
11134352
11217851
11290295
11291865
11291866
11298452
11358868
11358869
11390666
11418863
11437453
11438667
11445544
11449277
11458389
11493558
11566865
11668679
11668681
11688983
11748146
11748151
11809759
11820816
11846474
11875061
11884616
11886853
11892011
11900971
11904435
11914369
11934155
11934848
11964482
11973269
12015300
12062060
12091315
12117810
12145169
12231623
12351174
12351178
12361967
12372258
12372301
12376107
12397106
12421714
12431380
12435628
12435629
12441287
12441652
12447384
12466851
12471260
12488434
12490556
12533514
12571110
12588852
12588859
12652306
12774021
12781686
12787506
12812795
12835403
12842913
12865419
12869553
12952897
13129926
14502576
14504237
14511481
14603322
14645126
14668413
14681479
14701942
14736742
14736744
14757645
15005571
15014077
15075292
15084457
15105370
15105374
15136151
15142971
15183723
15215210
15218525
15229603
15231714
15261829
15302604
15314688
15329346
15355796
15371312
15389796
15452354
15469978
15485926
15539431
15567715
15576401
15576403
15576405
15616563
15618518
15623804
15668254
15680365
15737987
15739227
15778864
15789444
15817462
15857913
15899870
15959514
15987773
15987774
16001449
16055718
16061793
16098831
16109169
16109395
16141072
16141073
16155214
16207754
16210401
16214823
16256739
16284942
16291788
16291790
16357211
16364283
16364285
16368929
16376864
16397896
16407399
16414041
16459298
16459311
16467259
16467360
16494859
16537918
16564040
16571633
16602821
16627590
16647304
16678814
16740652
16806149
16831833
16839541
16847327
16887818
16893423
16912273
16912278
16943278
16956603
17027958
17035289
17086203
17117439
17220277
17260385
17304540
17321515
17327429
17331196
17389379
17428829
17442700
17478445
17488627
17490632
17504940
17504941
17507393
17507410
17553904
17596284
17609113
17611225
17611227
17882221
17908556
17922007
17936261
17936263
18003640
18036209
18061569
18076286
18094027
18161057
18171685
18224709
18241853
18268105
18287559
18296642
18324732
18327258
18332127
18336786
18339816
18351630
18358466
18374910
18381283
18400219
18403408
18462699
18478268
18497885
18498097
18539113
18554416
18556755
18590716
18590718
18611952
18617531
18635606
18660816
18662545
18692041
18697220
18701067
18701545
18722179
18773495
18778483
18781635
18787082
18794365
18798232
18820178
18832392
18927156
18929642
18930042
18953410
18973680
18974875
18991257
19000668
19004860
19056886
19097184
19103193
19103755
19122665
19141476
19168680
19213785
19223390
19234065
19270025
19286674
19298856
19300477
19334287
19339686
19369400
19379695
19389367
19390486
19415718
19417011
19436110
19439492
19474151
19487809
19502415
19542360
19556507
19562671
19589781
19592253
19592574
19607821
19615442
19628779
19666503
19686689
19720144
19732765
19737349
19737569
19767740
19774071
19786569
19825428
19835856
19850875
19877275
19877283
19896480
19956259
20035737
20040491
20067783
20074681
20108349
20148032
20159594
20175877
20211162
20347503
20350929
20450902
20460368
20463034
20483781
20484741
20508035
20516201
20533405
20534694
20551221
20562861
20572855
20573697
20609350
20610763
20637190
20678497
20689803
20692247
20708584
20727874
20730911
20842632
20849957
20880840
20934536
20960561
20978075
21045211
21057506
21062862
21068056
21093585
21098568
21106844
21205797
21209331
21246650
21267068
21292830
21337666
21445260
21466802
21472823
21552265
21565611
21664576
21677750
21682884
21689430
21693517
21704616
21731673
21752929
21761479
21763481
21763783
21775418
21786021
21791528
21822279
21829703
21831921
21896659
21912524
21920314
21924257
21982711
22001906
22007132
22040871
22075149
22096492
22103442
22121118
22132182
22179047
22182519
22186731
22265403
22278924
22342906
22383895
22529374
22537018
22542185
22549777
22554696
22554936
22573616
22595668
22595669
22607194
22669107
22696295
22698544
22737085
22745311
22780989
22841806
22865702
22889265
22902530
22912414
22921202
22945641
23006325
23024056
23060003
23071453
23109420
23154415
23201023
23213408
23213461
23217170
23260146
23283079
23324743
23332756
23359409
23383217
23416070
23471918
23471965
23482494
23521771
23618354
23620511
23637192
23651855
23707899
23712942
23729668
23775071
23822876
23823474
23824574
23884445
23900540
23924632
23955340
23993789
24104551
24401371
24449835
24496614
24627476

遺伝子オントロジー  (GO ID)

Biological Process

GO:0008344  adult locomotory behavior
GO:0048646  anatomical structure formation involved in morphogenesis
GO:0009653  anatomical structure morphogenesis
GO:0009952  anterior/posterior pattern formation
GO:0007596  blood coagulation
GO:0060441  branching involved in lung morphogenesis
GO:0048468  cell development
GO:0021533  cell differentiation in hindbrain
GO:0001708  cell fate specification
GO:0016568  chromatin modification
GO:0021904  dorsal/ventral neural tube patterning
GO:0009953  dorsal/ventral pattern formation
GO:0001705  ectoderm formation
GO:0031018  endocrine pancreas development
GO:0007492  endoderm development
GO:0001701  in utero embryonic development
GO:0030324  lung development
GO:0060487  lung epithelial cell differentiation
GO:0007275  multicellular organismal development
GO:0032289  myelin formation in the central nervous system
GO:0010719  negative regulation of epithelial to mesenchymal transition
GO:0033132  negative regulation of glucokinase activity
GO:0045665  negative regulation of neuron differentiation
GO:0043433  negative regulation of transcription factor activity
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0000433  negative regulation of transcription from RNA polymerase II promoter by glucose
GO:0048665  neuron fate specification
GO:0021779  oligodendrocyte cell fate commitment
GO:0007389  pattern specification process
GO:0040019  positive regulation of embryonic development
GO:0045666  positive regulation of neuron differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0000432  positive regulation of transcription from RNA polymerase II promoter by glucose
GO:0045945  positive regulation of transcription from RNA polymerase III promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0090009  primitive streak formation
GO:0030193  regulation of blood coagulation
GO:0010468  regulation of gene expression
GO:0051090  regulation of transcription factor activity
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0070741  response to interleukin-6
GO:0032525  somite rostral/caudal axis specification
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0008301  DNA bending activity
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0003690  double-stranded DNA binding
GO:0019900  kinase binding
GO:0005515  protein binding
GO:0019904  protein domain specific binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0046332  SMAD binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding