hepatic nuclear factor 4, alpha

詳細情報を見る

同義遺伝子名

Hnf-4, hepatic nuclear factor 4, alpha, Hnf4, Transcription factor 14, HNF-4-alpha, Tcf14, Transcription factor HNF-4, Hnf4a, Nuclear receptor 2A1, Nr2a1, HNF4 alpha, D19Mgi10, MODY1, HNF-4, Hepatocyte nuclear factor 4-alpha

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:14.40 脾臓:39.50 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:4.05 小脳:4.75 脳幹:- 脳梁:- 松果体:- 末梢神経:4.03 脊柱:4.35 網膜:4.20 目:4.34 動脈:- 静脈:4.02 リンパ節:3.79 末梢血:- 脾臓:3.95 胸腺:- 骨髄:3.79 脂肪:4.63 骨:3.93 皮膚:3.92
CAGE 大脳:0 小脳:- 脳幹:0 脳梁:- 松果体:- 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0.14 静脈:- リンパ節:0 末梢血:- 脾臓:0 胸腺:0 骨髄:- 脂肪:- 骨:0 皮膚:0
RNA-seq 大脳:1.97 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:55.20 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:32.70 腸:295.80 結腸:246.70     肝臓:371.10        肺:-    膀胱:- 腎臓:362.70 下垂体:- 甲状腺:- 副腎:- 膵臓:56.30 乳腺:- 唾液腺:-
GeneChip 子宮:3.92 胎盤:5.13 前立腺:4.01 卵巣:3.78 精巣:4.18 心臓:4.31 骨格筋:4.64 食道:- 胃:8.70 腸:10.10 結腸:- 肝臓:10.44 肺:4.56 膀胱:3.93 腎臓:10.58 下垂体:4.12 甲状腺:- 副腎:4.12 膵臓:4.87 乳腺:4.11 唾液腺:4.31
CAGE 子宮:0 胎盤:1.63 前立腺:0 卵巣:0.13 精巣:0 心臓:- 骨格筋:- 食道:- 胃:4.50 腸:5.01 結腸:5.18     肝臓:5.24    肺:0 膀胱:0.18 腎臓:- 下垂体:0 甲状腺:- 副腎:0.37 膵臓:3.53 乳腺:0 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:46.60        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_008261
Gene ID 15378
Unigene ID Mm.202383
Probe set ID 1421983_s_at  [Mouse430_2]
Ensembl ID ENSMUSG00000017950

オーソログ対応遺伝子

ヒト[10]  NM_000457, NM_001030003, NM_001030004, NM_175914, NM_178849, NM_178850
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1612587
7523862
7615825
7781998
7873404
7958910
7999795
8052626
8306889
8861101
8945471
9053305
9136932
9136933
9313765
9408084
9420335
9421506
9502734
9825865
9832509
9876182
10049364
10205167
10226013
10349636
10477299
10518495
10691738
10772805
10859308
10866673
10894496
11002334
11027604
11042159
11076861
11158324
11172041
11217851
11549321
11723233
11731232
11857799
11934848
11973269
11994307
12105231
12106016
12107181
12115031
12384562
12416993
12466152
12466851
12477932
12558604
12651943
12748966
12749857
12754525
12774017
12808453
12837957
12840167
12842913
12855700
14583614
14610273
14666509
14667415
14681479
14722127
15005571
15014077
15057908
15155787
15159395
15183723
15282747
15531365
15541721
15581617
15616563
15618518
15744310
15761495
15766748
15767668
15769825
15843801
15928313
16098509
16103213
16109169
16141072
16141073
16239260
16264197
16377800
16389552
16492670
16498401
16527247
16537911
16574644
16602821
16618389
16714383
16799975
16807375
16825189
16868071
16880515
16892179
16912278
16929032
16971476
16973757
16997394
17021047
17075876
17256722
17270735
17403778
17407387
17412818
17485727
17580084
17609113
17636037
17932483
17936262
17992261
17996499
18287559
18356246
18374325
18395097
18400219
18426912
18433744
18462699
18474611
18483185
18505824
18550708
18561282
18617288
18635606
18704925
18722179
18803630
18805788
18854136
19015235
19153222
19179483
19180647
19185577
19188435
19353766
19369401
19389805
19403103
19424486
19487809
19527784
19540905
19551907
19562671
19619492
19651776
19737349
19805521
19805548
19865483
19898610
19913509
19924231
19933841
20018873
20059953
20080099
20159955
20235219
20378774
20421289
20523905
20551221
20559753
20576917
20684663
20692235
20803549
20842632
20926756
20932939
21029356
21062863
21062980
21071704
21088200
21113154
21122108
21186337
21216305
21267068
21274867
21283715
21384409
21660050
21677750
21725089
21784065
21932312
22139130
22240483
22241473
22340507
22412967
22461026
22493904
22510988
22554936
22589549
22589735
22669107
22675511
22751438
22780989
22791717
22865702
22874919
22944911
22952853
22986531
23038264
23104559
23129810
23209428
23236470
23266329
23315968
23315977
23362348
23362349
23386589
23462932
23472758
23523371
23529017
23530060
23554936
23651855
23967086
24038112
24066149
24085033
24277929
24318876
24449835
24451200

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006637  acyl-CoA metabolic process
GO:0007596  blood coagulation
GO:0030154  cell differentiation
GO:0045216  cell-cell junction organization
GO:0007164  establishment of tissue polarity
GO:0042593  glucose homeostasis
GO:0030522  intracellular receptor-mediated signaling pathway
GO:0055088  lipid homeostasis
GO:0006629  lipid metabolic process
GO:0030308  negative regulation of cell growth
GO:0008285  negative regulation of cell proliferation
GO:0045930  negative regulation of mitotic cell cycle
GO:0050732  negative regulation of peptidyl-tyrosine phosphorylation
GO:0033159  negative regulation of protein import into nucleus, translocation
GO:0043433  negative regulation of transcription factor activity
GO:0042524  negative regulation of tyrosine phosphorylation of Stat5 protein
GO:0006591  ornithine metabolic process
GO:0055091  phospholipid homeostasis
GO:0045723  positive regulation of fatty acid biosynthetic process
GO:0045722  positive regulation of gluconeogenesis
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0010470  regulation of gastrulation
GO:0050796  regulation of insulin secretion
GO:0019216  regulation of lipid metabolic process
GO:0032534  regulation of microvillus assembly
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0009749  response to glucose stimulus
GO:0007548  sex differentiation
GO:0060395  SMAD protein signal transduction
GO:0043401  steroid hormone mediated signaling pathway
GO:0006351  transcription, DNA-dependent
GO:0070328  triglyceride homeostasis
GO:0006805  xenobiotic metabolic process

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0000062  acyl-CoA binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0005504  fatty acid binding
GO:0004879  ligand-dependent nuclear receptor activity
GO:0046872  metal ion binding
GO:0016290  palmitoyl-CoA hydrolase activity
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0005102  receptor binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0003707  steroid hormone receptor activity
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding
GO:0070491  transcription repressor binding
GO:0008270  zinc ion binding