solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

詳細情報を見る

同義遺伝子名

5HTT, MGC124314, Htt, MGC124313, 5-HTT, AI323329, Slc6a4, 5HT transporter, Sodium-dependent serotonin transporter, Sert

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:8.70 小脳:- 脳幹:222.50 脳梁:- 松果体:- 末梢神経:95.50 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:29.60 骨髄:- 脂肪:- 骨:50.10 皮膚:31.70
GeneChip 大脳:4.84 小脳:4.98 脳幹:- 脳梁:- 松果体:- 末梢神経:4.93 脊柱:4.83 網膜:5.14 目:5.17 動脈:- 静脈:6.54 リンパ節:4.82 末梢血:- 脾臓:5.98 胸腺:- 骨髄:8.99 脂肪:5.06 骨:8.81 皮膚:7.44
CAGE 大脳:0.10 小脳:- 脳幹:2.48 脳梁:- 松果体:- 末梢神経:- 脊柱:0.17 網膜:- 目:- 動脈:1.11 静脈:- リンパ節:1.12 末梢血:- 脾臓:1.94 胸腺:0 骨髄:- 脂肪:- 骨:3.21 皮膚:1.67
RNA-seq 大脳:2.01 小脳:2.01 脳幹:2.01 脳梁:2.01 松果体:2.01 末梢神経:2.01 脊柱:2.01 網膜:2.01 目:2.01 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:41.40 前立腺:- 卵巣:- 精巣:29.60 心臓:- 骨格筋:35.50 食道:- 胃:- 腸:184.90 結腸:35.20     肝臓:-        肺:10    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:848.90 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:4.97 胎盤:5.99 前立腺:5.29 卵巣:5.26 精巣:5.27 心臓:5.55 骨格筋:4.78 食道:- 胃:5.54 腸:7.53 結腸:- 肝臓:5.20 肺:6.50 膀胱:5.27 腎臓:5.94 下垂体:5.03 甲状腺:- 副腎:9.18 膵臓:6.51 乳腺:5.14 唾液腺:5.14
CAGE 子宮:0.44 胎盤:1.57 前立腺:0.51 卵巣:0.88 精巣:0.45 心臓:- 骨格筋:- 食道:- 胃:0 腸:4.51 結腸:4.14     肝臓:0    肺:1.59 膀胱:0.18 腎臓:- 下垂体:0 甲状腺:- 副腎:3.34 膵臓:2.19 乳腺:0.67 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_010484
Gene ID 15567
Unigene ID Mm.300318
Probe set ID 1417150_at  [Mouse430_2]
Ensembl ID ENSMUSG00000020838

オーソログ対応遺伝子

ヒト [0]  
ラット[2]  NM_013034

染色体

-

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

8507984
8747152
9037532
9073170
9165122
9459551
9489712
9547354
9636213
9673775
9826275
10076044
10203244
10349636
10436056
10541808
10565817
10611371
10841514
10947809
11042159
11050108
11060242
11076861
11157075
11158630
11172895
11181933
11217851
11245702
11298795
11320258
11487658
11517274
11875656
11901356
11981596
12031347
12183685
12374464
12388212
12401330
12446578
12464448
12466851
12477932
12533631
12546819
12584728
12598736
12614326
12634480
12757893
12764108
12807440
12814910
12897786
12968128
14583654
14602809
14610273
14622181
14625137
14625138
14645517
14653304
14653307
14653308
14681479
15009141
15078799
15105370
15312242
15365296
15469887
15514160
15539550
15589338
15589347
15649943
15652409
15672416
15763133
15809439
15834538
15858217
15886479
15940298
16023897
16024787
16125675
16141072
16141073
16183083
16339193
16380550
16542782
16546269
16602821
16638624
16707806
16775130
16782087
16873667
16884969
16905592
16939636
16951583
17150206
17151281
17151600
17177116
17187680
17202185
17234600
17250964
17306775
17452640
17510734
17687036
17692295
17949690
17987662
18003826
18187350
18209729
18211820
18241894
18304982
18317590
18356199
18385313
18541381
18573249
18599790
18663366
18685991
18789954
18794345
18824000
18854178
18957218
19016890
19033200
19070605
19095763
19121357
19145225
19176817
19179283
19192266
19208814
19306930
19308295
19426553
19482066
19494266
19577546
19585250
19621438
19625505
19646988
19679640
19698744
19713474
19747920
19782704
19817873
19864579
19892785
19907754
19960097
20007481
20019165
20032063
20060867
20128812
20216333
20219086
20347882
20371729
20440524
20470877
20576032
20676059
20677439
20818386
20847275
20854367
20863670
20921407
20955517
20974189
21068324
21070242
21129446
21177701
21192082
21216843
21238500
21262270
21267068
21282638
21299850
21303932
21308996
21419830
21437992
21439906
21454670
21490208
21491160
21512572
21531340
21549735
21666748
21677183
21787775
21814181
21818344
21835346
21846421
21857948
21864549
21886833
22013016
22049417
22140524
22366712
22373128
22412882
22431634
22431635
22457503
22544703
22553025
22572884
22623663
22623674
22824190
22833193
22843703
22951260
22956823
23089640
23142422
23223282
23238719
23291155
23305936
23336056
23431145
23536833
23558306
23567893
23678105
23678112
24012009
24077408
24083388
24107951
24167611
24570000
24760870

遺伝子オントロジー  (GO ID)

Biological Process

GO:0048854  brain morphogenesis
GO:0071321  cellular response to cGMP
GO:0071310  cellular response to organic substance
GO:0007623  circadian rhythm
GO:0007613  memory
GO:0015844  monoamine transport
GO:0021941  negative regulation of granule cell precursor proliferation
GO:0045665  negative regulation of neuron differentiation
GO:0046621  negative regulation of organ growth
GO:0032227  negative regulation of synaptic transmission, dopaminergic
GO:0006836  neurotransmitter transport
GO:0045787  positive regulation of cell cycle
GO:0010628  positive regulation of gene expression
GO:0051260  protein homooligomerization
GO:0051259  protein oligomerization
GO:0009636  response to toxin
GO:0006837  serotonin transport
GO:0051610  serotonin uptake
GO:0035176  social behavior
GO:0042713  sperm ejaculation
GO:0021794  thalamus development
GO:0006810  transport
GO:0042310  vasoconstriction

Cellular Component

GO:0005829  cytosol
GO:0012505  endomembrane system
GO:0005768  endosome
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0045121  membrane raft
GO:0043005  neuron projection
GO:0005886  plasma membrane

Molecular Function

GO:0051015  actin filament binding
GO:0019811  cocaine binding
GO:0008504  monoamine transmembrane transporter activity
GO:0017022  myosin binding
GO:0005328  neurotransmitter:sodium symporter activity
GO:0050998  nitric-oxide synthase binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0017137  Rab GTPase binding
GO:0015222  serotonin transmembrane transporter activity
GO:0005335  serotonin:sodium symporter activity
GO:0015293  symporter activity
GO:0017075  syntaxin-1 binding