insulin-like growth factor I receptor

同義遺伝子名

A330103N21Rik, CD221 antigen, line 186, hyft, D930020L01, Igf1r, IGF-1R, IGF-I receptor, insulin-like growth factor I receptor, Insulin-like growth factor 1 receptor precursor, Insulin-like growth factor I receptor, CD221

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:104.20

小脳:92.10

脳幹:31.80

脳梁:-

松果体:-

末梢神経:19.10

脊柱:189.10

網膜:450

目:121.60

動脈:168.80

静脈:-

リンパ節:64.80

末梢血:172.50

脾臓:-

胸腺:118.60

骨髄:38.50

脂肪:425.40

骨:137.80

皮膚:47.50

GeneChip

大脳:6.87

小脳:7.28

脳幹:-

脳梁:-

松果体:-

末梢神経:7.12

脊柱:7.03

網膜:6.40

目:6.64

動脈:-

静脈:7.81

リンパ節:6.58

末梢血:-

脾臓:6.24

胸腺:-

骨髄:7.71

脂肪:6.76

骨:7.13

皮膚:6.59

CAGE

大脳:3.29

小脳:-

脳幹:3.12

脳梁:-

松果体:-

末梢神経:-

脊柱:3.30

網膜:-

目:-

動脈:2.76

静脈:-

リンパ節:2.33

末梢血:-

脾臓:2.82

胸腺:2.74

骨髄:-

脂肪:-

骨:3.14

皮膚:3.07

RNA-seq

大脳:2.18

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:87.20

胎盤:13.80

前立腺:61.80

卵巣:91.90

精巣:22.20

心臓:93

骨格筋:-

食道:-

胃:65.50

腸:37

結腸:17.60

肝臓:18.10

肺:30.10

膀胱:66.20

腎臓:48.40

下垂体:129.20

甲状腺:-

副腎:-

膵臓:375.30

乳腺:45.70

唾液腺:-

GeneChip

子宮:7.58

胎盤:7.29

前立腺:7.76

卵巣:8.28

精巣:6.16

心臓:6.51

骨格筋:5.93

食道:-

胃:7.10

腸:6.63

結腸:-

肝臓:4.96

肺:7.27

膀胱:7.58

腎臓:9.16

下垂体:7.85

甲状腺:-

副腎:8

膵臓:7.11

乳腺:5.98

唾液腺:6.43

CAGE

子宮:3.25

胎盤:2.68

前立腺:3.39

卵巣:3.78

精巣:1.48

心臓:-

骨格筋:-

食道:-

胃:2.04

腸:1.92

結腸:2.27

肝臓:1.12

肺:3.51

膀胱:3.58

腎臓:-

下垂体:3.85

甲状腺:-

副腎:3.49

膵臓:3.36

乳腺:2.01

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.98

食道:-

胃:-

腸:-

結腸:-

肝臓:1.68

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_010513
Gene ID	16001
Unigene ID	Mm.275742
Probe set ID	1426565_at [Mouse430_2]
Ensembl ID	ENSMUSG00000005533

オーソログ対応遺伝子

ヒト[4]	NM_000875
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR003961	Fibronectin, type III
IPR008957	Fibronectin, type III-like fold
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0007409	axonogenesis
GO:0007420	brain development
GO:0030010	establishment of cell polarity
GO:0031017	exocrine pancreas development
GO:0006955	immune response
GO:0051389	inactivation of MAPKK activity
GO:0048009	insulin-like growth factor receptor signaling pathway
GO:0030238	male sex determination
GO:0030879	mammary gland development
GO:0043066	negative regulation of apoptosis
GO:0043409	negative regulation of MAPKKK cascade
GO:0010656	negative regulation of muscle cell apoptosis
GO:0051898	negative regulation of protein kinase B signaling cascade
GO:0031175	neuron projection development
GO:0009887	organ morphogenesis
GO:0048015	phosphoinositide-mediated signaling
GO:0016310	phosphorylation
GO:0030335	positive regulation of cell migration
GO:0032467	positive regulation of cytokinesis
GO:0051054	positive regulation of DNA metabolic process
GO:0045740	positive regulation of DNA replication
GO:0043410	positive regulation of MAPKKK cascade
GO:0051897	positive regulation of protein kinase B signaling cascade
GO:0090031	positive regulation of steroid hormone biosynthetic process
GO:0060740	prostate gland epithelium morphogenesis
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0051291	protein heterooligomerization
GO:0051262	protein tetramerization
GO:0046328	regulation of JNK cascade
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0005901	caveola
GO:0016021	integral to membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0016020	membrane
GO:0043005	neuron projection
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0001965	G-protein alpha-subunit binding
GO:0042802	identical protein binding
GO:0043559	insulin binding
GO:0005158	insulin receptor binding
GO:0043560	insulin receptor substrate binding
GO:0005520	insulin-like growth factor binding
GO:0031994	insulin-like growth factor I binding
GO:0005010	insulin-like growth factor receptor activity
GO:0016301	kinase activity
GO:0000166	nucleotide binding
GO:0043548	phosphoinositide 3-kinase binding
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0004714	transmembrane receptor protein tyrosine kinase activity

insulin-like growth factor I receptor

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function