insulin II

詳細情報を見る

同義遺伝子名

AA986540, insulin II, Insulin-2 precursor, Ins2, Mody, Ins-2, Mody4, proinsulin

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:3.50

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:19.10

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:21.60

末梢血:-

脾臓:26.30

胸腺:9.90

骨髄:-

脂肪:-

骨:-

皮膚:-

GeneChip

大脳:6.26

小脳:6.34

脳幹:-

脳梁:-

松果体:-

末梢神経:6.05

脊柱:6.32

網膜:7.22

目:6.50

動脈:-

静脈:6.34

リンパ節:6.07

末梢血:-

脾臓:6.23

胸腺:-

骨髄:6.03

脂肪:7.09

骨:6.19

皮膚:6.22

CAGE

大脳:0

小脳:-

脳幹:0

脳梁:-

松果体:-

末梢神経:-

脊柱:0

網膜:-

目:-

動脈:0

静脈:-

リンパ節:0

末梢血:-

脾臓:0

胸腺:0.82

骨髄:-

脂肪:-

骨:0

皮膚:0

RNA-seq

大脳:0.75

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:258.60

心臓:18.60

骨格筋:-

食道:-

胃:32.70

腸:-

結腸:-

肝臓:-

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:6.50

唾液腺:-

GeneChip

子宮:6.21

胎盤:6.20

前立腺:5.98

卵巣:5.97

精巣:6.45

心臓:6.48

骨格筋:6.63

食道:-

胃:6.29

腸:6.18

結腸:-

肝臓:6.35

肺:5.94

膀胱:6.22

腎臓:6.40

下垂体:6.27

甲状腺:-

副腎:6.04

膵臓:14.28

乳腺:6.37

唾液腺:6.32

CAGE

子宮:0

胎盤:0.31

前立腺:0

卵巣:0

精巣:0

心臓:-

骨格筋:-

食道:-

胃:4.65

腸:1.05

結腸:6.21

肝臓:3.34

肺:0

膀胱:0

腎臓:-

下垂体:0

甲状腺:-

副腎:0

膵臓:9.91

乳腺:0

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:-

肝臓:4.72

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_008387
Gene ID	16334
Unigene ID	Mm.49460
Probe set ID	1422446_x_at [Mouse430_2]
Ensembl ID	ENSMUSG00000000215

オーソログ対応遺伝子

ヒト[1]	NM_000207, NM_001185097, NM_001185098
ラット[1]	NM_019129, NM_019130, NM_001185098

染色体

遺伝子ファミリー (Interpro ID)

IPR016179	Insulin-like
IPR004825	Insulin/IGF/relaxin

遺伝子オントロジー (GO ID)

Biological Process

GO:0007257	activation of JUN kinase activity
GO:0000187	activation of MAPK activity
GO:0032148	activation of protein kinase B activity
GO:0006953	acute-phase response
GO:0046631	alpha-beta T cell activation
GO:0070059	apoptosis in response to endoplasmic reticulum stress
GO:0005975	carbohydrate metabolic process
GO:0006983	ER overload response
GO:0055089	fatty acid homeostasis
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0042593	glucose homeostasis
GO:0006006	glucose metabolic process
GO:0015758	glucose transport
GO:0008286	insulin receptor signaling pathway
GO:0016042	lipid catabolic process
GO:0000165	MAPKKK cascade
GO:0007520	myoblast fusion
GO:0014902	myotube differentiation
GO:0002674	negative regulation of acute inflammatory response
GO:0045922	negative regulation of fatty acid metabolic process
GO:0045818	negative regulation of glycogen catabolic process
GO:0033861	negative regulation of NAD(P)H oxidase activity
GO:0042177	negative regulation of protein catabolic process
GO:0032460	negative regulation of protein oligomerization
GO:0050709	negative regulation of protein secretion
GO:0045861	negative regulation of proteolysis
GO:0060266	negative regulation of respiratory burst during acute inflammatory response
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0008284	positive regulation of cell proliferation
GO:0032270	positive regulation of cellular protein metabolic process
GO:0050715	positive regulation of cytokine secretion
GO:0045740	positive regulation of DNA replication
GO:0046326	positive regulation of glucose import
GO:0045725	positive regulation of glycogen biosynthetic process
GO:0045821	positive regulation of glycolysis
GO:0046628	positive regulation of insulin receptor signaling pathway
GO:0043410	positive regulation of MAPKKK cascade
GO:0045840	positive regulation of mitosis
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0043552	positive regulation of phosphoinositide 3-kinase activity
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0051897	positive regulation of protein kinase B signaling cascade
GO:0060267	positive regulation of respiratory burst
GO:0006521	regulation of cellular amino acid metabolic process
GO:0010468	regulation of gene expression
GO:0042325	regulation of phosphorylation
GO:0043393	regulation of protein binding
GO:0032880	regulation of protein localization
GO:0050708	regulation of protein secretion
GO:0022898	regulation of transmembrane transporter activity
GO:0060070	Wnt receptor signaling pathway through beta-catenin
GO:0042060	wound healing

Cellular Component

GO:0005737	cytoplasm
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005634	nucleus
GO:0030141	secretory granule
GO:0005732	small nucleolar ribonucleoprotein complex

Molecular Function

GO:0005179	hormone activity
GO:0005158	insulin receptor binding
GO:0005159	insulin-like growth factor receptor binding
GO:0002020	protease binding
GO:0032403	protein complex binding

insulin II

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function