potassium large conductance calcium-activated channel, subfamily M, alpha member 1

詳細情報を見る

同義遺伝子名

BK channel alpha subunit, mSlo, BKCA alpha, mSlo1, Kcnma, MaxiK, Slo homolog, Slo1, Maxi K channel, Slowpoke homolog, K(VCA)alpha, Slo-alpha, KCa1.1, Kcnma1, BK channel, Slo

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:31.80 脳梁:- 松果体:- 末梢神経:19.10 脊柱:- 網膜:32.10 目:15.20 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:26.30 胸腺:- 骨髄:- 脂肪:- 骨:12.50 皮膚:7.90
GeneChip 大脳:7.52 小脳:6.44 脳幹:- 脳梁:- 松果体:- 末梢神経:5.54 脊柱:6.05 網膜:5.87 目:4.53 動脈:- 静脈:4.04 リンパ節:3.99 末梢血:- 脾臓:3.89 胸腺:- 骨髄:3.88 脂肪:3.90 骨:3.99 皮膚:3.87
CAGE 大脳:3.97 小脳:- 脳幹:3.28 脳梁:- 松果体:- 末梢神経:- 脊柱:2.76 網膜:- 目:- 動脈:2.07 静脈:- リンパ節:1.35 末梢血:- 脾臓:0 胸腺:1.26 骨髄:- 脂肪:- 骨:2.29 皮膚:1.63
RNA-seq 大脳:4.95 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:35.50 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:198.50 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:6.50 唾液腺:-
GeneChip 子宮:3.78 胎盤:3.85 前立腺:5.18 卵巣:4.28 精巣:3.95 心臓:4.06 骨格筋:5.64 食道:- 胃:4.14 腸:4.19 結腸:- 肝臓:3.95 肺:3.85 膀胱:4.68 腎臓:4.06 下垂体:4.53 甲状腺:- 副腎:5.35 膵臓:4.39 乳腺:4.27 唾液腺:5.01
CAGE 子宮:2.35 胎盤:0.11 前立腺:2.52 卵巣:3.11 精巣:0.45 心臓:- 骨格筋:- 食道:- 胃:1.91 腸:1.49 結腸:1.89     肝臓:0.26    肺:0.55 膀胱:3.53 腎臓:- 下垂体:3.60 甲状腺:- 副腎:4.10 膵臓:0 乳腺:0.78 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.35 食道:- 胃:- 腸:- 結腸:-     肝臓:0        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_010610
Gene ID 16531
Unigene ID Mm.458374
Probe set ID 1424848_at  [Mouse430_2]
Ensembl ID ENSMUSG00000063142

オーソログ対応遺伝子

ヒト[8]  NM_001014797, NM_001161352, NM_001161353, NM_002247
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007628  adult walking behavior
GO:0042491  auditory receptor cell differentiation
GO:0048469  cell maturation
GO:0030007  cellular potassium ion homeostasis
GO:0007623  circadian rhythm
GO:0060082  eye blink reflex
GO:0006811  ion transport
GO:0045475  locomotor rhythm
GO:0060073  micturition
GO:0045794  negative regulation of cell volume
GO:0050885  neuromuscular process controlling balance
GO:0043065  positive regulation of apoptosis
GO:0006813  potassium ion transport
GO:0051260  protein homooligomerization
GO:0051289  protein homotetramerization
GO:0019228  regulation of action potential in neuron
GO:0032344  regulation of aldosterone metabolic process
GO:0034765  regulation of ion transmembrane transport
GO:0042391  regulation of membrane potential
GO:0042312  regulation of vasodilation
GO:0060087  relaxation of vascular smooth muscle
GO:0051592  response to calcium ion
GO:0034465  response to carbon monoxide
GO:0031960  response to corticosteroid stimulus
GO:0043627  response to estrogen stimulus
GO:0001666  response to hypoxia
GO:0006970  response to osmotic stress
GO:0009268  response to pH
GO:0046541  saliva secretion
GO:0007605  sensory perception of sound
GO:0060083  smooth muscle contraction involved in micturition
GO:0007268  synaptic transmission
GO:0055085  transmembrane transport
GO:0006810  transport
GO:0042311  vasodilation

Cellular Component

GO:0016324  apical plasma membrane
GO:0005901  caveola
GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0030425  dendrite
GO:0005783  endoplasmic reticulum
GO:0009897  external side of plasma membrane
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0045211  postsynaptic membrane
GO:0048787  presynaptic active zone membrane
GO:0043234  protein complex
GO:0043195  terminal button
GO:0019031  viral envelope
GO:0019012  virion
GO:0008076  voltage-gated potassium channel complex

Molecular Function

GO:0003779  actin binding
GO:0015269  calcium-activated potassium channel activity
GO:0005216  ion channel activity
GO:0060072  large conductance calcium-activated potassium channel activity
GO:0046872  metal ion binding
GO:0005267  potassium channel activity
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0042803  protein homodimerization activity
GO:0005244  voltage-gated ion channel activity
GO:0005249  voltage-gated potassium channel activity