kit oncogene

 詳細情報を見る

同義遺伝子名

Tr-kit, CD117, Steel Factor Receptor, Bs, kit oncogene, SCFR, Ssm, c-KIT, Mast/stem cell growth factor receptor precursor, W, Kit, Sl, belly-spot, c-kit, Proto-oncogene tyrosine-protein kinase Kit, Dominant white spotting, Fdc, CD117 antigen

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:112.90 小脳:534.20 脳幹:158.90 脳梁:- 松果体:- 末梢神経:19.10 脊柱:189.10 網膜:32.10 目:98.80 動脈:84.40 静脈:- リンパ節:- 末梢血:57.50 脾臓:- 胸腺:69.20 骨髄:141 脂肪:- 骨:12.50 皮膚:71.30
GeneChip 大脳:7.48 小脳:9.54 脳幹:- 脳梁:- 松果体:- 末梢神経:8.32 脊柱:6.70 網膜:5.98 目:6.74 動脈:- 静脈:7.19 リンパ節:7.39 末梢血:- 脾臓:7.80 胸腺:- 骨髄:8.33 脂肪:6.91 骨:8.13 皮膚:5.80
CAGE 大脳:4.54 小脳:- 脳幹:2.83 脳梁:- 松果体:- 末梢神経:- 脊柱:2.92 網膜:- 目:- 動脈:3.24 静脈:- リンパ節:3.50 末梢血:- 脾臓:3.70 胸腺:2.68 骨髄:- 脂肪:- 骨:3.54 皮膚:2.75
RNA-seq 大脳:7.08 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:87.20 胎盤:41.40 前立腺:- 卵巣:344.70 精巣:110.80 心臓:18.60 骨格筋:- 食道:- 胃:- 腸:- 結腸:17.60     肝臓:-        肺:371.60    膀胱:- 腎臓:24.20 下垂体:129.20 甲状腺:- 副腎:- 膵臓:56.30 乳腺:349.30 唾液腺:-
GeneChip 子宮:6.71 胎盤:10.10 前立腺:5.43 卵巣:7.81 精巣:7.01 心臓:5.39 骨格筋:5.11 食道:- 胃:8.08 腸:8.35 結腸:- 肝臓:6.31 肺:9.97 膀胱:7.30 腎臓:6.26 下垂体:5.75 甲状腺:- 副腎:5.41 膵臓:6.39 乳腺:9.25 唾液腺:7.11
CAGE 子宮:2.88 胎盤:5.04 前立腺:1.69 卵巣:3.79 精巣:1.97 心臓:- 骨格筋:- 食道:- 胃:3.29 腸:2.38 結腸:3.24     肝臓:2.62    肺:4.95 膀胱:3.44 腎臓:- 下垂体:2.25 甲状腺:- 副腎:1.42 膵臓:3.64 乳腺:3.64 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.23 食道:- 胃:- 腸:- 結腸:-     肝臓:1.59        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_021099
Gene ID 16590
Unigene ID Mm.247073
Probe set ID 1452514_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000005672

オーソログ対応遺伝子

ヒト[2]  NM_000222, NM_001093772
ラット [0]  

染色体

5C3.3  [75,970,941  -  76,052,747]

遺伝子ファミリー (Interpro ID)

IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR020685  Tyrosine-protein kinase
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR016243  Tyrosine-protein kinase, CSF-1/PDGF receptor
IPR020933  Tyrosine-protein kinase, fibroblast growth factor receptor, conserved region
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0031532  actin cytoskeleton reorganization
GO:0000187  activation of MAPK activity
GO:0060326  cell chemotaxis
GO:0030154  cell differentiation
GO:0006935  chemotaxis
GO:0019221  cytokine-mediated signaling pathway
GO:0002371  dendritic cell cytokine production
GO:0050910  detection of mechanical stimulus involved in sensory perception of sound
GO:0035162  embryonic hemopoiesis
GO:0050673  epithelial cell proliferation
GO:0030218  erythrocyte differentiation
GO:0007281  germ cell development
GO:0008354  germ cell migration
GO:0035234  germ cell programmed cell death
GO:0006687  glycosphingolipid metabolic process
GO:0048565  gut development
GO:0030097  hemopoiesis
GO:0002327  immature B cell differentiation
GO:0006954  inflammatory response
GO:0030032  lamellipodium assembly
GO:0002320  lymphoid progenitor cell differentiation
GO:0002551  mast cell chemotaxis
GO:0032762  mast cell cytokine production
GO:0043303  mast cell degranulation
GO:0060374  mast cell differentiation
GO:0030318  melanocyte differentiation
GO:0002573  myeloid leukocyte differentiation
GO:0002318  myeloid progenitor cell differentiation
GO:0043069  negative regulation of programmed cell death
GO:0001541  ovarian follicle development
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0016310  phosphorylation
GO:0043473  pigmentation
GO:0048066  pigmentation during development
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0010628  positive regulation of gene expression
GO:0046427  positive regulation of JAK-STAT cascade
GO:0048170  positive regulation of long-term neuronal synaptic plasticity
GO:0043406  positive regulation of MAP kinase activity
GO:0043410  positive regulation of MAPKKK cascade
GO:0045747  positive regulation of Notch signaling pathway
GO:0031274  positive regulation of pseudopodium assembly
GO:0051091  positive regulation of transcription factor activity
GO:0042511  positive regulation of tyrosine phosphorylation of Stat1 protein
GO:0042517  positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0042523  positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0007243  protein kinase cascade
GO:0008360  regulation of cell shape
GO:0048070  regulation of pigmentation during development
GO:0009314  response to radiation
GO:0048103  somatic stem cell division
GO:0035019  somatic stem cell maintenance
GO:0007286  spermatid development
GO:0007283  spermatogenesis
GO:0048863  stem cell differentiation
GO:0030217  T cell differentiation
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway
GO:0008542  visual learning

Cellular Component

GO:0001669  acrosomal vesicle
GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0009897  external side of plasma membrane
GO:0005615  extracellular space
GO:0016021  integral to membrane
GO:0009898  internal side of plasma membrane
GO:0016020  membrane
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0019955  cytokine binding
GO:0016301  kinase activity
GO:0046872  metal ion binding
GO:0000166  nucleotide binding
GO:0002020  protease binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0004672  protein kinase activity
GO:0004713  protein tyrosine kinase activity
GO:0004716  receptor signaling protein tyrosine kinase activity
GO:0005020  stem cell factor receptor activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups
GO:0004714  transmembrane receptor protein tyrosine kinase activity