Kruppel-like factor 4 (gut)

詳細情報を見る

同義遺伝子名

Epithelial zinc-finger protein EZF, EZF, Klf4, Ezf, Kruppel-like factor 4 (gut), Krueppel-like factor 4, Gut-enriched krueppel-like factor, Zie, Gklf

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:18.40 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:7.60 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:12.50 皮膚:-
GeneChip 大脳:6.61 小脳:6.22 脳幹:- 脳梁:- 松果体:- 末梢神経:7.27 脊柱:6.44 網膜:6.30 目:9.87 動脈:- 静脈:11.25 リンパ節:7.47 末梢血:- 脾臓:7.34 胸腺:- 骨髄:8.12 脂肪:8.83 骨:8.68 皮膚:12.28
CAGE 大脳:1.65 小脳:- 脳幹:1.97 脳梁:- 松果体:- 末梢神経:- 脊柱:1.73 網膜:- 目:- 動脈:3.81 静脈:- リンパ節:2.47 末梢血:- 脾臓:1.87 胸腺:1.99 骨髄:- 脂肪:- 骨:2.53 皮膚:5.42
RNA-seq 大脳:1.63 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:133 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:3.30 唾液腺:-
GeneChip 子宮:9.70 胎盤:9.51 前立腺:8.46 卵巣:7.98 精巣:9.99 心臓:9.91 骨格筋:9.54 食道:- 胃:12.06 腸:12.02 結腸:- 肝臓:5.16 肺:11.80 膀胱:10.50 腎臓:6.57 下垂体:6.79 甲状腺:- 副腎:8.20 膵臓:7.46 乳腺:8.28 唾液腺:7.36
CAGE 子宮:4.68 胎盤:3.87 前立腺:2.79 卵巣:2.74 精巣:2.41 心臓:- 骨格筋:- 食道:- 胃:6.17 腸:4.00 結腸:5.29     肝臓:1.45    肺:4.66 膀胱:3.74 腎臓:- 下垂体:1.92 甲状腺:- 副腎:2.72 膵臓:2.66 乳腺:2.47 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:3.41 食道:- 胃:- 腸:- 結腸:-     肝臓:1.32        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_010637
Gene ID 16600
Unigene ID Mm.432504
Probe set ID 1417394_at  [Mouse430_2]
Ensembl ID ENSMUSG00000003032

オーソログ対応遺伝子

ヒト[2]  NM_004235
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

8702718
8940147
9218496
9422764
9428642
9443972
9651398
10330488
10349636
10366853
10431239
10556311
10666450
10725249
10749849
10767086
10913614
10922068
11042159
11076861
11217851
11326268
11544199
11741941
12015290
12034813
12087155
12427745
12466851
12477932
12581631
12736219
12845703
12970361
14610273
14627709
15358627
15618518
15687259
15740636
15806166
15820306
15825076
15831758
16141072
16141073
16169848
16185820
16192310
16230531
16244670
16628254
16670755
16954384
16954505
17016435
17017123
17060454
17130451
17278886
17339326
17508399
17671182
17719562
17762869
17878366
18197146
18243172
18264089
18287559
18375530
18379898
18390749
18396140
18400104
18435741
18469187
18483411
18504508
18511453
18554416
18724799
18799693
18983970
19022741
19041854
19066578
19074836
19092943
19109406
19137014
19147802
19224983
19268913
19272164
19387067
19412182
19531492
19539755
19619540
19669938
19751731
19762425
19779097
19796622
19815778
19816951
19901072
20051481
20059953
20071344
20305087
20347813
20362542
20378849
20412781
20433848
20439457
20454664
20646110
20724706
20799856
20802152
20816834
20946687
20980461
21051695
21056461
21070761
21076063
21085182
21131959
21132436
21182892
21267068
21290164
21311564
21316587
21348597
21398290
21473687
21531817
21589869
21670299
21670502
21673106
21677750
21685331
21731673
21750654
21803296
21985610
22001906
22105482
22155367
22160720
22203039
22206865
22232554
22306741
22307056
22345706
22355722
22384261
22449968
22491752
22538816
22653776
22723415
22745808
22811558
22907754
22937066
23007394
23065825
23065827
23160196
23202735
23334579
23372771
23430263
23451207
23515309
23558921
23643161
23708003
23733190
23748610
23846700
23867820
23919723
24030402
24076321
24129709
24148820
24156273
24161396
24204315
24261709
24599951
24616223

遺伝子オントロジー  (GO ID)

Biological Process

GO:0030154  cell differentiation
GO:0071363  cellular response to growth factor stimulus
GO:0009913  epidermal cell differentiation
GO:0048730  epidermis morphogenesis
GO:0045444  fat cell differentiation
GO:0043154  negative regulation of caspase activity
GO:0090051  negative regulation of cell migration involved in sprouting angiogenesis
GO:0008285  negative regulation of cell proliferation
GO:0070373  negative regulation of ERK1 and ERK2 cascade
GO:0034115  negative regulation of heterotypic cell-cell adhesion
GO:0045415  negative regulation of interleukin-8 biosynthetic process
GO:0014740  negative regulation of muscle hyperplasia
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0014067  negative regulation of phosphoinositide 3-kinase cascade
GO:0051898  negative regulation of protein kinase B signaling cascade
GO:0060761  negative regulation of response to cytokine stimulus
GO:0048662  negative regulation of smooth muscle cell proliferation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0046985  positive regulation of hemoglobin biosynthetic process
GO:0051247  positive regulation of protein metabolic process
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0031077  post-embryonic camera-type eye development
GO:0035166  post-embryonic hemopoiesis
GO:0045595  regulation of cell differentiation
GO:0042127  regulation of cell proliferation
GO:0043551  regulation of phosphoinositide 3-kinase activity
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0010033  response to organic substance
GO:0032526  response to retinoic acid
GO:0019827  stem cell maintenance
GO:0006366  transcription from RNA polymerase II promoter
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0000785  chromatin
GO:0000790  nuclear chromatin
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0003690  double-stranded DNA binding
GO:0046872  metal ion binding
GO:0003676  nucleic acid binding
GO:0035014  phosphoinositide 3-kinase regulator activity
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding