lymphocyte protein tyrosine kinase

詳細情報を見る

同義遺伝子名

p56, lymphocyte protein tyrosine kinase, Proto-oncogene tyrosine-protein kinase LCK, Lck, Lsk-t, p56-LCK, Hck-3, LSK, Lymphocyte cell-specific protein-tyrosine kinase

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:8.70 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:421.90 静脈:- リンパ節:32.40 末梢血:330.70 脾臓:39.50 胸腺:928.70 骨髄:- 脂肪:- 骨:12.50 皮膚:7.90
GeneChip 大脳:5.45 小脳:4.90 脳幹:- 脳梁:- 松果体:- 末梢神経:5.18 脊柱:5.05 網膜:6.08 目:5.39 動脈:- 静脈:5.48 リンパ節:11.98 末梢血:- 脾臓:11.45 胸腺:- 骨髄:8.12 脂肪:6.15 骨:7.39 皮膚:5.39
CAGE 大脳:0.18 小脳:- 脳幹:0.07 脳梁:- 松果体:- 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0.77 静脈:- リンパ節:4.18 末梢血:- 脾臓:3.16 胸腺:5.86 骨髄:- 脂肪:- 骨:1.30 皮膚:0.77
RNA-seq 大脳:0.78 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:7.40 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:112.50 副腎:- 膵臓:- 乳腺:26.10 唾液腺:54
GeneChip 子宮:8.27 胎盤:5.30 前立腺:5.24 卵巣:6.04 精巣:5.99 心臓:5.27 骨格筋:6.07 食道:- 胃:5.55 腸:6.87 結腸:- 肝臓:5.57 肺:7.13 膀胱:5.17 腎臓:5.37 下垂体:5.50 甲状腺:- 副腎:5.77 膵臓:5.52 乳腺:7.70 唾液腺:5.58
CAGE 子宮:0.97 胎盤:0 前立腺:0.51 卵巣:0.35 精巣:0 心臓:- 骨格筋:- 食道:- 胃:0 腸:0.95 結腸:2.32     肝臓:0.64    肺:2.72 膀胱:1.01 腎臓:- 下垂体:0 甲状腺:- 副腎:1.58 膵臓:0 乳腺:1.38 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.13 食道:- 胃:- 腸:- 結腸:-     肝臓:1.29        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_010693
Gene ID 16818
Unigene ID Mm.293753
Probe set ID 1425396_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000000409

オーソログ対応遺伝子

ヒト[4]  NM_001042771, NM_005356
ラット[1]  NM_001100709, NM_005356

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1279202
1370487
1370884
1409609
1505025
1579166
1594248
1643308
1645445
1675432
1684952
1706070
1708890
1730679
1765007
1889815
1978328
1988541
2000388
2037292
2107025
2341157
2404338
2416464
2574141
2759422
2845126
2850479
3081813
3166417
3352600
3463975
3501824
7486703
7489757
7499277
7515496
7536925
7547689
7590745
7632929
7636195
7648394
7664803
7685110
7719022
7719023
7761462
7774634
7807014
7829080
7889413
7926807
7949731
7980442
8074710
8094369
8095010
8098006
8104199
8143742
8171035
8175795
8276397
8288240
8363569
8371758
8385609
8390965
8393038
8406449
8413237
8413611
8415697
8415706
8421674
8464923
8469988
8521470
8522158
8551236
8570203
8576115
8661721
8683122
8757961
8806656
8824815
8858916
8889548
8910336
8934569
8934570
8943574
9002646
9045636
9045930
9115297
9169414
9177270
9366400
9370921
9390273
9396778
9548458
9558087
9581568
9620552
9725213
9754575
9802979
9820525
9870664
10072519
10097132
10330160
10349636
10358158
10415032
10441215
10453000
10523617
10553045
10636863
10646608
10679268
10684862
10713104
10742150
10781838
10843386
10940892
11005864
11021796
11034371
11042159
11076861
11114734
11145654
11217851
11254359
11470773
11741956
11744391
11745376
11847223
11854322
11870621
12077322
12218089
12218114
12244310
12352968
12466305
12466851
12477932
12570875
12645942
12732664
12759418
12808452
12922168
13679040
14515253
14610273
14625311
14685278
14706337
14734719
14749125
14752163
14757743
14993658
15034040
15121848
15128794
15210755
15357954
15465914
15489334
15522954
15592455
15603741
15634756
15687496
15699074
15735648
15784897
15814704
15817477
15905556
15972627
16111633
16141072
16141073
16216891
16354835
16474166
16501569
16602821
16709819
16923964
16966372
17060632
17897956
17932036
18069898
18660530
18799693
18976935
18981123
19109140
19164599
19577230
19668367
19917692
20007709
20126650
20237292
20300113
20305788
20360068
20372794
20417561
20498282
20724731
20729329
20826747
20844195
20876849
20974990
21048115
21061443
21103055
21245484
21267068
21339332
21357543
21487392
21917715
22222369
22281390
22529380
22623673
22683124
22828953
23007847
23296706
23427257
23616926
23715271
23793062
24034254
24101551
24311692

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0050853  B cell receptor signaling pathway
GO:0007166  cell surface receptor linked signal transduction
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0016310  phosphorylation
GO:0045588  positive regulation of gamma-delta T cell differentiation
GO:0010628  positive regulation of gene expression
GO:0050870  positive regulation of T cell activation
GO:0042523  positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0070474  positive regulation of uterine smooth muscle contraction
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0050856  regulation of T cell receptor signaling pathway
GO:0051209  release of sequestered calcium ion into cytosol
GO:0042493  response to drug
GO:0042542  response to hydrogen peroxide
GO:0009612  response to mechanical stimulus
GO:0010038  response to metal ion
GO:0030217  T cell differentiation

Cellular Component

GO:0005737  cytoplasm
GO:0030139  endocytic vesicle
GO:0001772  immunological synapse
GO:0016020  membrane
GO:0045121  membrane raft
GO:0000242  pericentriolar material
GO:0005886  plasma membrane

Molecular Function

GO:0003823  antigen binding
GO:0005524  ATP binding
GO:0051117  ATPase binding
GO:0042609  CD4 receptor binding
GO:0042610  CD8 receptor binding
GO:0001948  glycoprotein binding
GO:0016301  kinase activity
GO:0004715  non-membrane spanning protein tyrosine kinase activity
GO:0000166  nucleotide binding
GO:0043548  phosphoinositide 3-kinase binding
GO:0005515  protein binding
GO:0008022  protein C-terminus binding
GO:0032403  protein complex binding
GO:0004672  protein kinase activity
GO:0019901  protein kinase binding
GO:0019903  protein phosphatase binding
GO:0004722  protein serine/threonine phosphatase activity
GO:0004713  protein tyrosine kinase activity
GO:0042169  SH2 domain binding
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups