leptin

詳細情報を見る

leptin, Ob, ob, obese, Obesity factor, Leptin precursor, Lep

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

Refseq ID	NM_008493
Gene ID	16846
Unigene ID	Mm.277072
Probe set ID	1422582_at [Mouse430_2]
Ensembl ID	ENSMUSG00000059201

ヒト[1]	NM_000230
ラット [0]

IPR009079	Four-helical cytokine-like, core
IPR000065	Obesity factor

GO:0060612	adipose tissue development
GO:0008343	adult feeding behavior
GO:0008206	bile acid metabolic process
GO:0003300	cardiac muscle hypertrophy
GO:0021954	central nervous system neuron development
GO:0008203	cholesterol metabolic process
GO:0042755	eating behavior
GO:0006112	energy reserve metabolic process
GO:0009062	fatty acid catabolic process
GO:0006006	glucose metabolic process
GO:0006114	glycerol biosynthetic process
GO:0042445	hormone metabolic process
GO:0030073	insulin secretion
GO:0033210	leptin-mediated signaling pathway
GO:0050901	leukocyte tethering or rolling
GO:0006629	lipid metabolic process
GO:0043066	negative regulation of apoptosis
GO:0032099	negative regulation of appetite
GO:0070093	negative regulation of glucagon secretion
GO:0009892	negative regulation of metabolic process
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045906	negative regulation of vasoconstriction
GO:0001542	ovulation from ovarian follicle
GO:0001890	placenta development
GO:0008284	positive regulation of cell proliferation
GO:0048639	positive regulation of developmental growth
GO:0046628	positive regulation of insulin receptor signaling pathway
GO:0043270	positive regulation of ion transport
GO:0046427	positive regulation of JAK-STAT cascade
GO:0043410	positive regulation of MAPKKK cascade
GO:0045639	positive regulation of myeloid cell differentiation
GO:0042307	positive regulation of protein import into nucleus
GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0008217	regulation of blood pressure
GO:0045598	regulation of fat cell differentiation
GO:0006111	regulation of gluconeogenesis
GO:0050796	regulation of insulin secretion
GO:0030300	regulation of intestinal cholesterol absorption
GO:0060587	regulation of lipoprotein lipid oxidation
GO:0019222	regulation of metabolic process
GO:0001932	regulation of protein amino acid phosphorylation
GO:0050810	regulation of steroid biosynthetic process
GO:0002021	response to dietary excess
GO:0032868	response to insulin stimulus
GO:0007165	signal transduction
GO:0007260	tyrosine phosphorylation of STAT protein

GO:0005737	cytoplasm
GO:0005576	extracellular region
GO:0005615	extracellular space

GO:0008083	growth factor activity
GO:0005179	hormone activity
GO:0051428	peptide hormone receptor binding
GO:0005515	protein binding

leptin

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function