toll-like receptor 7

詳細情報を見る

同義遺伝子名

Toll-like receptor 7 precursor, toll-like receptor 7, Tlr7

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:53.80 小脳:55.30 脳幹:- 脳梁:- 松果体:- 末梢神経:133.80 脊柱:- 網膜:96.40 目:68.40 動脈:84.40 静脈:- リンパ節:1069.30 末梢血:71.90 脾臓:92.20 胸腺:39.50 骨髄:- 脂肪:- 骨:87.70 皮膚:142.50
GeneChip 大脳:4.92 小脳:4.75 脳幹:- 脳梁:- 松果体:- 末梢神経:4.77 脊柱:5 網膜:4.86 目:5.47 動脈:- 静脈:5.26 リンパ節:7.60 末梢血:- 脾臓:7.64 胸腺:- 骨髄:6.58 脂肪:5.46 骨:6.50 皮膚:4.70
CAGE 大脳:1.17 小脳:- 脳幹:1.16 脳梁:- 松果体:- 末梢神経:- 脊柱:0.91 網膜:- 目:- 動脈:2.57 静脈:- リンパ節:4.53 末梢血:- 脾臓:3.04 胸腺:2.44 骨髄:- 脂肪:- 骨:2.45 皮膚:2.29
RNA-seq 大脳:0.84 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:43.60 胎盤:41.40 前立腺:- 卵巣:80.40 精巣:96.10 心臓:18.60 骨格筋:35.50 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:40.20    膀胱:- 腎臓:32.20 下垂体:25.80 甲状腺:- 副腎:- 膵臓:140.70 乳腺:58.80 唾液腺:-
GeneChip 子宮:5.02 胎盤:5.03 前立腺:5.31 卵巣:4.96 精巣:5.15 心臓:5.48 骨格筋:5.34 食道:- 胃:4.95 腸:4.71 結腸:- 肝臓:5.70 肺:5.20 膀胱:5.14 腎臓:4.89 下垂体:4.73 甲状腺:- 副腎:5.18 膵臓:5.09 乳腺:5.36 唾液腺:5.26
CAGE 子宮:1.72 胎盤:0.94 前立腺:0.84 卵巣:1.86 精巣:0 心臓:- 骨格筋:- 食道:- 胃:1.35 腸:0.72 結腸:1.11     肝臓:1.85    肺:2.36 膀胱:1.58 腎臓:- 下垂体:0.70 甲状腺:- 副腎:2.50 膵臓:0.84 乳腺:1.76 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:0.89 食道:- 胃:- 腸:- 結腸:-     肝臓:1.54        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_133211
Gene ID 170743
Unigene ID Mm.239793
Probe set ID 1422010_at  [Mouse430_2]
Ensembl ID ENSMUSG00000044583

オーソログ対応遺伝子

ヒト[1]  NM_016562
ラット[1]  NM_001097582

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

10349636
11042159
11076861
11217851
11812998
12032557
12466851
12477932
12730667
12819136
12875990
14976261
14976262
15034168
15210814
15561968
15630134
15634897
15654326
15723075
15767370
15804288
16039576
16105838
16141072
16141073
16230478
16260486
16361354
16368889
16407888
16446426
16461338
16537810
16602821
16612387
16623926
16706797
16709748
16810635
16886064
16973388
16973389
16979664
16985170
17008311
17040905
17082628
17111347
17114424
17132722
17135446
17277123
17289654
17339429
17339488
17371961
17404496
17446350
17452530
17456769
17513736
17572686
17608805
17675254
17878370
17897860
17942529
17950005
17981792
17997333
18025224
18083110
18097414
18157820
18180038
18250417
18250459
18261938
18287559
18305481
18322178
18337753
18340381
18368052
18383384
18394314
18406377
18424698
18480244
18490763
18492657
18521959
18544685
18581336
18606711
18691914
18794297
18820679
18824599
18978796
19016073
19047436
19120489
19124731
19157556
19188597
19200759
19251253
19290047
19299691
19333924
19382893
19426550
19430477
19445181
19451267
19454661
19464849
19494335
19559490
19568424
19570822
19587008
19641044
19648281
19710454
19735273
19843574
19846276
19848448
19890064
19944565
19966212
19995952
20007584
20042593
20065291
20089701
20107183
20187710
20200270
20231379
20304804
20360404
20368279
20383149
20451253
20495560
20562862
20624950
20628601
20668698
20811154
20865117
20953969
20956347
21037581
21078886
21115688
21115693
21131420
21157038
21187399
21235537
21239713
21253574
21267068
21282509
21340621
21357542
21383246
21389257
21430225
21435586
21469103
21480215
21482736
21515789
21525388
21538349
21540549
21623379
21625574
21632720
21683627
21690387
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21765012
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21918198
21966467
21998589
22105994
22114338
22138643
22170637
22184724
22206014
22227568
22251703
22312111
22315415
22371392
22421433
22422888
22490865
22531913
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22543675
22565312
22610069
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22634614
22636319
22659029
22666391
22691272
22704622
22704624
22745379
22753494
22776817
22777843
22786773
22787112
22821982
22837197
22837203
22844124
22896628
22896636
22916010
22927956
22945807
22962685
22988104
23019335
23023703
23024275
23028824
23029281
23136362
23142781
23154432
23290966
23303674
23314004
23318200
23325805
23338611
23370539
23376919
23382219
23382559
23446849
23561801
23584892
23616654
23658804
23677145
23761632
23790156
23843519
23918369
24018482
24038087
24041926
24042114
24105635
24145511
24191131
24227841
24254490
24342772
24376264
24474776
24637670
24698267
24711620

遺伝子オントロジー  (GO ID)

Biological Process

GO:0051607  defense response to virus
GO:0007252  I-kappaB phosphorylation
GO:0006955  immune response
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0002282  microglial cell activation during immune response
GO:0002755  MyD88-dependent toll-like receptor signaling pathway
GO:0052033  pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity
GO:0032722  positive regulation of chemokine production
GO:0045356  positive regulation of interferon-alpha biosynthetic process
GO:0045359  positive regulation of interferon-beta biosynthetic process
GO:0045078  positive regulation of interferon-gamma biosynthetic process
GO:0032755  positive regulation of interleukin-6 production
GO:0045416  positive regulation of interleukin-8 biosynthetic process
GO:0032757  positive regulation of interleukin-8 production
GO:0042346  positive regulation of NF-kappaB import into nucleus
GO:0042221  response to chemical stimulus
GO:0007165  signal transduction
GO:0034154  toll-like receptor 7 signaling pathway
GO:0002224  toll-like receptor signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0031410  cytoplasmic vesicle
GO:0032009  early phagosome
GO:0005783  endoplasmic reticulum
GO:0005768  endosome
GO:0016021  integral to membrane
GO:0005764  lysosome
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0003725  double-stranded RNA binding
GO:0008144  drug binding
GO:0005515  protein binding
GO:0003727  single-stranded RNA binding
GO:0035197  siRNA binding
GO:0004888  transmembrane receptor activity