Yamaguchi sarcoma viral (v-yes-1) oncogene homolog

詳細情報を見る

同義遺伝子名

Lyn, Tyrosine-protein kinase Lyn, AA407514, Yamaguchi sarcoma viral (v-yes-1) oncogene homolog, Hck-2

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:20.80 小脳:18.40 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:7.60 動脈:- 静脈:- リンパ節:226.80 末梢血:143.80 脾臓:263.30 胸腺:9.90 骨髄:743.60 脂肪:- 骨:112.70 皮膚:39.60
GeneChip 大脳:5.80 小脳:6.56 脳幹:- 脳梁:- 松果体:- 末梢神経:5.67 脊柱:5.75 網膜:4.76 目:5.46 動脈:- 静脈:6.55 リンパ節:10.53 末梢血:- 脾臓:10.58 胸腺:- 骨髄:10.27 脂肪:6.94 骨:9.73 皮膚:5.66
CAGE nodata
RNA-seq 大脳:1.58 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:130.90 胎盤:- 前立腺:- 卵巣:11.50 精巣:- 心臓:55.80 骨格筋:35.50 食道:- 胃:- 腸:110.90 結腸:-     肝臓:-        肺:110.50    膀胱:- 腎臓:72.50 下垂体:- 甲状腺:112.50 副腎:- 膵臓:18.80 乳腺:32.60 唾液腺:54
GeneChip 子宮:8.31 胎盤:7.42 前立腺:6.88 卵巣:7.51 精巣:5.19 心臓:6.99 骨格筋:6.51 食道:- 胃:7.18 腸:8.09 結腸:- 肝臓:7.94 肺:9.24 膀胱:6.30 腎臓:6.73 下垂体:5.88 甲状腺:- 副腎:6.19 膵臓:6.66 乳腺:7.67 唾液腺:5.85
CAGE nodata
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.81 食道:- 胃:- 腸:- 結腸:-     肝臓:4.94        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_001111096
Gene ID 17096
Unigene ID Mm.317331
Probe set ID 1425598_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000042228

オーソログ対応遺伝子

ヒト[5]  NM_001111097, NM_002350
ラット[6]  NM_001111098, NM_030857

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1337939
1710766
1825055
2017160
2482828
2574141
2674853
2759422
3561390
7499277
7525568
7536925
7542761
7584145
7585947
7589891
7650392
7758954
7774913
7893599
8034026
8128248
8276397
8395016
8535092
8627181
8635998
8943574
9000133
9036984
9064343
9151903
9202419
9252121
9294206
9314552
9353253
9480991
9547345
9573010
9586639
9590225
9601638
9620599
9653087
9687507
9712716
9730885
9808051
9890970
9892356
10349636
10358768
10464165
10510355
10556550
10594694
10611342
10640270
10684859
10713104
10823839
10829070
10844001
10852954
10872802
10903718
10922068
10945997
11042159
11076861
11110698
11114734
11166177
11168595
11217851
11238587
11238611
11238661
11245687
11356033
11389024
11435302
11509585
11672542
11698501
11724799
11739500
11739737
11826756
11884485
11895777
11896394
11920569
12056610
12089510
12192036
12239221
12466851
12471110
12471124
12477932
12486102
12563261
12663500
12710978
12821647
12874221
12882960
12896983
12902486
14525964
14594209
14656892
14726379
14871838
15034025
15166241
15210764
15219462
15339845
15367693
15451030
15477350
15489334
15516974
15542585
15664155
15665117
15745956
15814670
15935067
15985541
15998803
16034130
16116174
16140274
16141072
16141073
16176929
16177087
16249387
16272347
16278813
16282349
16301670
16339523
16418722
16425036
16456001
16527351
16602821
16616866
16705093
16731527
16772601
16782884
16788103
16801133
16859680
16872848
16920712
17039569
17086186
17095622
17182584
17192284
17207856
17218386
17233630
17277164
17404251
17513616
17588471
17617561
17640867
17853409
17918263
18246197
18250449
18346837
18354197
18519649
18550847
18625913
18644892
18682390
18794338
18984583
19064729
19100679
19118221
19150426
19171907
19201855
19255189
19273622
19285079
19305493
19362019
19380785
19403835
19541367
19587372
19590497
19620313
19696895
19940238
19949072
19966213
20004975
20042579
20101614
20189992
20299514
20304029
20308635
20385881
20394076
20512127
20624892
20858858
21088116
21098033
21220696
21297004
21307254
21464326
21592972
21602433
21683628
21791602
21860019
21911371
21928281
21964606
22057631
22246800
22302035
22364282
22431203
22450804
22473614
22491248
22511754
22675576
22679019
22777522
22798664
22942428
23071785
23169140
23338238
23382690
23396948
23447687
23457006
23509253
23584088
23616926
23692855
23776171
23940344
24108461
24127553
24338528
24376269
24379120
24385425
24440445
24552351
24559674
24733849

遺伝子オントロジー  (GO ID)

Biological Process

GO:0030262  apoptotic nuclear changes
GO:0001782  B cell homeostasis
GO:0050853  B cell receptor signaling pathway
GO:0071300  cellular response to retinoic acid
GO:0050663  cytokine secretion
GO:0030218  erythrocyte differentiation
GO:0002774  Fc receptor mediated inhibitory signaling pathway
GO:0002431  Fc receptor mediated stimulatory signaling pathway
GO:0042541  hemoglobin biosynthetic process
GO:0030097  hemopoiesis
GO:0002553  histamine secretion by mast cell
GO:0002768  immune response-regulating cell surface receptor signaling pathway
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0031663  lipopolysaccharide-mediated signaling pathway
GO:0030889  negative regulation of B cell proliferation
GO:0008285  negative regulation of cell proliferation
GO:0070373  negative regulation of ERK1 and ERK2 cascade
GO:0043407  negative regulation of MAP kinase activity
GO:0070667  negative regulation of mast cell proliferation
GO:0002762  negative regulation of myeloid leukocyte differentiation
GO:0001933  negative regulation of protein amino acid phosphorylation
GO:0010741  negative regulation of protein kinase cascade
GO:0034136  negative regulation of toll-like receptor 2 signaling pathway
GO:0034144  negative regulation of toll-like receptor 4 signaling pathway
GO:0031175  neuron projection development
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0016310  phosphorylation
GO:0002576  platelet degranulation
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0051272  positive regulation of cellular component movement
GO:0060369  positive regulation of Fc receptor mediated stimulatory signaling pathway
GO:0060252  positive regulation of glial cell proliferation
GO:0070668  positive regulation of mast cell proliferation
GO:0010976  positive regulation of neuron projection development
GO:0070447  positive regulation of oligodendrocyte progenitor proliferation
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0043552  positive regulation of phosphoinositide 3-kinase activity
GO:0042327  positive regulation of phosphorylation
GO:0070304  positive regulation of stress-activated protein kinase signaling pathway
GO:0042531  positive regulation of tyrosine phosphorylation of STAT protein
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0002902  regulation of B cell apoptosis
GO:0050855  regulation of B cell receptor signaling pathway
GO:0033628  regulation of cell adhesion mediated by integrin
GO:0001817  regulation of cytokine production
GO:0050707  regulation of cytokine secretion
GO:0070372  regulation of ERK1 and ERK2 cascade
GO:0045646  regulation of erythrocyte differentiation
GO:0050727  regulation of inflammatory response
GO:0033003  regulation of mast cell activation
GO:0043304  regulation of mast cell degranulation
GO:0090025  regulation of monocyte chemotaxis
GO:0051279  regulation of release of sequestered calcium ion into cytosol
GO:0006974  response to DNA damage stimulus
GO:0009725  response to hormone stimulus
GO:0007165  signal transduction
GO:0002513  tolerance induction to self antigen
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0034666  alpha2-beta1 integrin complex
GO:0005623  cell
GO:0005913  cell-cell adherens junction
GO:0005737  cytoplasm
GO:0005794  Golgi apparatus
GO:0043231  intracellular membrane-bounded organelle
GO:0016020  membrane
GO:0045121  membrane raft
GO:0030061  mitochondrial crista
GO:0005758  mitochondrial intermembrane space
GO:0031966  mitochondrial membrane
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0014069  postsynaptic density

Molecular Function

GO:0005524  ATP binding
GO:0019899  enzyme binding
GO:0005128  erythropoietin receptor binding
GO:0043015  gamma-tubulin binding
GO:0043208  glycosphingolipid binding
GO:0005178  integrin binding
GO:0016301  kinase activity
GO:0004715  non-membrane spanning protein tyrosine kinase activity
GO:0000166  nucleotide binding
GO:0051219  phosphoprotein binding
GO:0005161  platelet-derived growth factor receptor binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0004672  protein kinase activity
GO:0004713  protein tyrosine kinase activity
GO:0005102  receptor binding
GO:0017124  SH3 domain binding
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups
GO:0031625  ubiquitin protein ligase binding