MAD homolog 1 (Drosophila)

詳細情報を見る

同義遺伝子名

MAD homolog 1 (Drosophila), Dwarfin-A, Mothers against DPP homolog 1, Madr1, Mothers against decapentaplegic homolog 1, MusMLP, mMad1, Dwf-A, Mad-related protein 1, Madh1, Smad 1, Smad1, SMAD 1, AI528653, Mlp1, Mothers-against-DPP-related 1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:52.10 小脳:294.70 脳幹:222.50 脳梁:- 松果体:- 末梢神経:114.70 脊柱:236.40 網膜:160.70 目:15.20 動脈:506.30 静脈:- リンパ節:10.80 末梢血:86.30 脾臓:79 胸腺:108.70 骨髄:12.80 脂肪:- 骨:125.20 皮膚:39.60
GeneChip 大脳:6.71 小脳:7.20 脳幹:- 脳梁:- 松果体:- 末梢神経:8.11 脊柱:6.95 網膜:6.01 目:6.56 動脈:- 静脈:7.06 リンパ節:7.77 末梢血:- 脾臓:6.69 胸腺:- 骨髄:5.94 脂肪:6.93 骨:6.21 皮膚:7.53
CAGE 大脳:3.14 小脳:- 脳幹:3.08 脳梁:- 松果体:- 末梢神経:- 脊柱:3.14 網膜:- 目:- 動脈:3.19 静脈:- リンパ節:3.67 末梢血:- 脾臓:2.12 胸腺:2.74 骨髄:- 脂肪:- 骨:2.45 皮膚:4.00
RNA-seq 大脳:2.31 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:87.20 胎盤:- 前立腺:61.80 卵巣:103.40 精巣:36.90 心臓:18.60 骨格筋:71 食道:- 胃:65.50 腸:- 結腸:88.10     肝臓:9.10        肺:30.10    膀胱:132.40 腎臓:56.40 下垂体:38.80 甲状腺:- 副腎:- 膵臓:84.40 乳腺:62 唾液腺:-
GeneChip 子宮:8.45 胎盤:7.11 前立腺:7.72 卵巣:8.20 精巣:7.51 心臓:7.01 骨格筋:6.83 食道:- 胃:7.83 腸:8.81 結腸:- 肝臓:6.85 肺:7.40 膀胱:7.92 腎臓:6.40 下垂体:7.64 甲状腺:- 副腎:7.32 膵臓:6.25 乳腺:7.15 唾液腺:7.58
CAGE 子宮:3.73 胎盤:2.92 前立腺:3.62 卵巣:3.41 精巣:1.18 心臓:- 骨格筋:- 食道:- 胃:3.45 腸:3.09 結腸:3.12     肝臓:2.68    肺:3.34 膀胱:3.41 腎臓:- 下垂体:3.42 甲状腺:- 副腎:3.04 膵臓:2.75 乳腺:2.87 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.68 食道:- 胃:- 腸:- 結腸:-     肝臓:2.80        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_008539
Gene ID 17125
Unigene ID Mm.223717
Probe set ID 1416081_at  [Mouse430_2]
Ensembl ID ENSMUSG00000031681

オーソログ対応遺伝子

ヒト[2]  NM_001003688, NM_005900
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

8799132
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10224145
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0030509  BMP signaling pathway
GO:0060348  bone development
GO:0060038  cardiac muscle cell proliferation
GO:0051216  cartilage development
GO:0071407  cellular response to organic cyclic substance
GO:0007276  gamete generation
GO:0030902  hindbrain development
GO:0042592  homeostatic process
GO:0000165  MAPKKK cascade
GO:0001710  mesodermal cell fate commitment
GO:0030901  midbrain development
GO:0008285  negative regulation of cell proliferation
GO:0002051  osteoblast fate commitment
GO:0045597  positive regulation of cell differentiation
GO:0010628  positive regulation of gene expression
GO:0045669  positive regulation of osteoblast differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006468  protein amino acid phosphorylation
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0042493  response to drug
GO:0007183  SMAD protein complex assembly
GO:0006351  transcription, DNA-dependent
GO:0007179  transforming growth factor beta receptor signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0005622  intracellular
GO:0005637  nuclear inner membrane
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0070410  co-SMAD binding
GO:0003677  DNA binding
GO:0070411  I-SMAD binding
GO:0042802  identical protein binding
GO:0046872  metal ion binding
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0003700  transcription factor activity