methyl CpG binding protein 2

詳細情報を見る

同義遺伝子名

BB130002, 1500041B07Rik, methyl CpG binding protein 2, Mecp2, Methyl-CpG-binding protein 2, Mbd5, MeCP2, MeCP-2 protein, WBP10

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:1.70 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:13.20 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:9.48 小脳:9.21 脳幹:- 脳梁:- 松果体:- 末梢神経:8.50 脊柱:9.04 網膜:9.30 目:8.19 動脈:- 静脈:7.75 リンパ節:8.16 末梢血:- 脾臓:7.93 胸腺:- 骨髄:8.07 脂肪:8.17 骨:8.10 皮膚:7.66
CAGE 大脳:3.93 小脳:- 脳幹:3.81 脳梁:- 松果体:- 末梢神経:- 脊柱:3.87 網膜:- 目:- 動脈:3.27 静脈:- リンパ節:3.51 末梢血:- 脾臓:3.29 胸腺:3.44 骨髄:- 脂肪:- 骨:3.10 皮膚:3.37
RNA-seq 大脳:1.87 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:8.16 胎盤:6.85 前立腺:8.23 卵巣:8.24 精巣:5.68 心臓:7.85 骨格筋:8.10 食道:- 胃:7.33 腸:7.30 結腸:- 肝臓:6.52 肺:8.46 膀胱:7.79 腎臓:7.72 下垂体:8.45 甲状腺:- 副腎:8.76 膵臓:6.80 乳腺:7.92 唾液腺:7.83
CAGE 子宮:3.34 胎盤:2.83 前立腺:3.38 卵巣:3.21 精巣:1.60 心臓:- 骨格筋:- 食道:- 胃:2.36 腸:2.49 結腸:2.62     肝臓:2.70    肺:3.53 膀胱:3.24 腎臓:- 下垂体:3.67 甲状腺:- 副腎:3.30 膵臓:3.16 乳腺:2.76 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.78 食道:- 胃:- 腸:- 結腸:-     肝臓:2.92        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_001081979
Gene ID 17257
Unigene ID Mm.414303
Probe set ID 1460246_at  [Mouse430_2]
Ensembl ID ENSMUSG00000031393

オーソログ対応遺伝子

ヒト[4]  NM_001110792, NM_004992
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1631115
2180582
8001979
8563762
8589515
8769643
9160753
9171351
9774669
10349636
10369871
10723722
10888872
11042159
11058114
11076861
11160912
11217851
11242117
11242118
11371345
11441023
11809720
12160743
12427740
12442230
12466851
12477932
12727440
12904583
12928486
14519686
14593183
14593184
14610273
14643676
14681479
14973779
15034150
15069197
15115765
15342650
15345242
15351775
15489334
15492925
15519245
15548546
15608638
15696166
15733677
15757975
15780747
15809268
15837557
15888476
15917271
15939091
15939760
15975715
15977646
16087343
16116096
16141072
16141073
16199017
16251199
16251272
16354910
16380085
16399702
16439027
16446138
16467389
16543822
16549272
16549521
16581518
16602821
16613900
16680199
16682435
16754645
16782889
16848781
17046689
17050729
17108082
17114649
17204503
17237885
17267601
17278996
17289941
17296936
17309881
17383101
17395475
17464364
17532643
17544925
17546630
17584923
17635839
17701895
17913925
17920015
17936729
17965622
17994015
17997046
18006868
18032561
18058824
18159237
18203756
18223199
18287934
18295506
18306326
18321864
18321865
18329113
18334558
18425126
18511691
18534925
18557922
18571096
18687363
18690105
18701457
18761004
18778693
18799693
18817733
18834926
18989361
19000991
19012748
19109157
19138667
19167498
19177165
19208815
19225110
19234456
19296534
19331822
19339616
19359374
19369296
19386901
19414073
19427855
19521566
19524074
19571810
19602036
19620975
19628041
19674087
19710912
19741133
19793977
19812320
19820693
19843474
19898468
19900619
19906978
19932741
19958389
19966177
19998492
20007372
20010955
20025874
20040383
20042730
20045053
20093853
20107077
20138994
20159591
20163734
20188178
20188665
20193660
20200124
20203171
20211142
20298210
20368621
20381590
20392952
20392956
20504995
20599664
20625242
20625482
20633611
20634955
20679481
20711186
20713094
20716963
20732392
20816763
20869373
20921386
20921395
20951208
21068835
21085180
21212100
21232545
21239731
21267068
21296130
21307327
21307341
21330301
21350014
21420494
21435439
21471155
21471397
21482354
21497756
21511710
21609470
21636743
21677750
21716289
21753013
21765426
21791604
21829232
21831886
21880923
21901842
21909962
21982370
22009741
22037496
22119903
22127389
22138506
22174313
22186023
22230884
22231481
22249109
22252744
22262897
22297041
22302819
22334035
22355564
22357867
22374971
22375006
22378884
22395464
22412847
22425995
22500635
22615490
22653753
22677942
22709555
22815516
22822052
22865604
22891354
22919518
22923521
22973007
23011033
23015442
23022455
23026749
23027959
23035095
23055506
23077217
23112857
23180809
23185431
23197715
23227269
23238573
23246925
23259945
23260135
23335972
23362347
23392116
23452848
23462290
23558747
23643691
23659895
23684790
23705018
23750231
23770565
23770587
23791832
23875667
23892605
23948639
23986203
23992846
23992847
24009314
24060648
24067915
24078059
24089468
24109855
24188180
24283265
24285883
24523563
24626160
24671997

遺伝子オントロジー  (GO ID)

Biological Process

GO:0008344  adult locomotory behavior
GO:0001662  behavioral fear response
GO:0007420  brain development
GO:0032048  cardiolipin metabolic process
GO:0050432  catecholamine secretion
GO:0006576  cellular biogenic amine metabolic process
GO:0021549  cerebellum development
GO:0006342  chromatin silencing
GO:0016358  dendrite development
GO:0009790  embryonic development
GO:0006349  genetic imprinting
GO:0008211  glucocorticoid metabolic process
GO:0006541  glutamine metabolic process
GO:0016573  histone acetylation
GO:0016571  histone methylation
GO:0006020  inositol metabolic process
GO:0007612  learning
GO:0007616  long-term memory
GO:0060291  long-term synaptic potentiation
GO:0007613  memory
GO:0006122  mitochondrial electron transport, ubiquinol to cytochrome c
GO:0033555  multicellular organismal response to stress
GO:0035067  negative regulation of histone acetylation
GO:0031061  negative regulation of histone methylation
GO:0043524  negative regulation of neuron apoptosis
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0001976  neurological system process involved in regulation of systemic arterial blood pressure
GO:0050905  neuromuscular process
GO:0050884  neuromuscular process controlling posture
GO:0030182  neuron differentiation
GO:0042551  neuron maturation
GO:0031175  neuron projection development
GO:0009405  pathogenesis
GO:0046470  phosphatidylcholine metabolic process
GO:0008284  positive regulation of cell proliferation
GO:0051965  positive regulation of synaptogenesis
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0009791  post-embryonic development
GO:0019230  proprioception
GO:0008104  protein localization
GO:0060079  regulation of excitatory postsynaptic membrane potential
GO:0010468  regulation of gene expression
GO:0040029  regulation of gene expression, epigenetic
GO:0002087  regulation of respiratory gaseous exchange by neurological system process
GO:0048167  regulation of synaptic plasticity
GO:0006355  regulation of transcription, DNA-dependent
GO:0007585  respiratory gaseous exchange
GO:0001666  response to hypoxia
GO:0019233  sensory perception of pain
GO:0035176  social behavior
GO:0001964  startle response
GO:0007416  synapse assembly
GO:0007268  synaptic transmission
GO:0006351  transcription, DNA-dependent
GO:0021591  ventricular system development
GO:0008542  visual learning

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0000792  heterochromatin
GO:0000790  nuclear chromatin
GO:0005634  nucleus
GO:0043234  protein complex

Molecular Function

GO:0003682  chromatin binding
GO:0031490  chromatin DNA binding
GO:0003677  DNA binding
GO:0010385  double-stranded methylated DNA binding
GO:0019899  enzyme binding
GO:0000400  four-way junction DNA binding
GO:0008327  methyl-CpG binding
GO:0003729  mRNA binding
GO:0005515  protein binding
GO:0019904  protein domain specific binding
GO:0047485  protein N-terminus binding
GO:0035197  siRNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding
GO:0045322  unmethylated CpG binding