multiple endocrine neoplasia 1

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同義遺伝子名

multiple endocrine neoplasia 1, Menin, AW045611, menin, Men1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:97.20 小脳:128.90 脳幹:31.80 脳梁:- 松果体:257.80 末梢神経:191.10 脊柱:47.30 網膜:96.40 目:91.20 動脈:- 静脈:- リンパ節:226.80 末梢血:71.90 脾臓:26.30 胸腺:39.50 骨髄:102.60 脂肪:- 骨:87.70 皮膚:63.30
GeneChip 大脳:8.27 小脳:8.25 脳幹:- 脳梁:- 松果体:- 末梢神経:8.66 脊柱:8.23 網膜:6.56 目:6.47 動脈:- 静脈:8.07 リンパ節:7.80 末梢血:- 脾臓:8.13 胸腺:- 骨髄:7.85 脂肪:7.63 骨:7.38 皮膚:6.76
CAGE 大脳:2.95 小脳:- 脳幹:3.01 脳梁:- 松果体:- 末梢神経:- 脊柱:3.11 網膜:- 目:- 動脈:2.14 静脈:- リンパ節:2.17 末梢血:- 脾臓:2.37 胸腺:3.06 骨髄:- 脂肪:- 骨:2.09 皮膚:2.50
RNA-seq 大脳:10.01 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:218.10 胎盤:69 前立腺:- 卵巣:68.90 精巣:22.20 心臓:- 骨格筋:- 食道:- 胃:163.60 腸:- 結腸:70.50     肝臓:18.10        肺:80.30    膀胱:- 腎臓:56.40 下垂体:12.90 甲状腺:- 副腎:- 膵臓:28.10 乳腺:111 唾液腺:54
GeneChip 子宮:8.30 胎盤:7.86 前立腺:7.96 卵巣:8.28 精巣:7.56 心臓:7.25 骨格筋:6.96 食道:- 胃:7.83 腸:7.84 結腸:- 肝臓:7.79 肺:7.95 膀胱:7.66 腎臓:8.14 下垂体:8.01 甲状腺:- 副腎:7.91 膵臓:7.44 乳腺:7.28 唾液腺:7.78
CAGE 子宮:2.81 胎盤:2.76 前立腺:2.51 卵巣:2.65 精巣:2.92 心臓:- 骨格筋:- 食道:- 胃:2.36 腸:2.65 結腸:2.27     肝臓:2.58    肺:2.74 膀胱:2.33 腎臓:- 下垂体:2.87 甲状腺:- 副腎:2.82 膵臓:3.04 乳腺:2.68 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.59 食道:- 胃:- 腸:- 結腸:-     肝臓:3.41        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_001168488
Gene ID 17283
Unigene ID Mm.12917
Probe set ID 1416347_at  [Mouse430_2]
Ensembl ID ENSMUSG00000024947

オーソログ対応遺伝子

ヒト[7]  NM_000244, NM_130799, NM_130800, NM_130801, NM_130802, NM_130803, NM_130804
ラット[1]  NM_019208, NM_130799, NM_130800, NM_130801, NM_130802, NM_130803, NM_130804

染色体

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007050  cell cycle arrest
GO:0016568  chromatin modification
GO:0006338  chromatin remodeling
GO:0009790  embryonic development
GO:0048704  embryonic skeletal system morphogenesis
GO:0030097  hemopoiesis
GO:0034968  histone lysine methylation
GO:0016571  histone methylation
GO:0001776  leukocyte homeostasis
GO:0000165  MAPKKK cascade
GO:0060135  maternal process involved in female pregnancy
GO:0045786  negative regulation of cell cycle
GO:0008285  negative regulation of cell proliferation
GO:0045736  negative regulation of cyclin-dependent protein kinase activity
GO:0046329  negative regulation of JNK cascade
GO:0046621  negative regulation of organ growth
GO:0045668  negative regulation of osteoblast differentiation
GO:0001933  negative regulation of protein amino acid phosphorylation
GO:0051974  negative regulation of telomerase activity
GO:0043433  negative regulation of transcription factor activity
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0001503  ossification
GO:0002076  osteoblast development
GO:0002051  osteoblast fate commitment
GO:0060021  palate development
GO:0043065  positive regulation of apoptosis
GO:0043280  positive regulation of caspase activity
GO:0045597  positive regulation of cell differentiation
GO:0051781  positive regulation of cell division
GO:0031062  positive regulation of histone methylation
GO:0045669  positive regulation of osteoblast differentiation
GO:0032092  positive regulation of protein binding
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0030511  positive regulation of transforming growth factor beta receptor signaling pathway
GO:0032925  regulation of activin receptor signaling pathway
GO:0006355  regulation of transcription, DNA-dependent
GO:0006974  response to DNA damage stimulus
GO:0010332  response to gamma radiation
GO:0009411  response to UV
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0000785  chromatin
GO:0032154  cleavage furrow
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0035097  histone methyltransferase complex
GO:0016363  nuclear matrix
GO:0005634  nucleus
GO:0043234  protein complex

Molecular Function

GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0003690  double-stranded DNA binding
GO:0000400  four-way junction DNA binding
GO:0018024  histone-lysine N-methyltransferase activity
GO:0005515  protein binding
GO:0030674  protein binding, bridging
GO:0047485  protein N-terminus binding
GO:0070412  R-SMAD binding
GO:0043565  sequence-specific DNA binding
GO:0000403  Y-form DNA binding