met proto-oncogene

詳細情報を見る

同義遺伝子名

SF receptor, Met, Met proto-oncogene tyrosine kinase, HGF/SF receptor, HGF receptor, c-Met, Hepatocyte growth factor receptor precursor, HGFR, met proto-oncogene, Scatter factor receptor, HGF

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:10.40 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:60.80 動脈:- 静脈:- リンパ節:10.80 末梢血:43.10 脾臓:13.20 胸腺:- 骨髄:12.80 脂肪:- 骨:25 皮膚:39.60
GeneChip 大脳:4.56 小脳:4.47 脳幹:- 脳梁:- 松果体:- 末梢神経:4.60 脊柱:4.75 網膜:4.48 目:4.52 動脈:- 静脈:5.05 リンパ節:4.84 末梢血:- 脾臓:4.98 胸腺:- 骨髄:4.82 脂肪:6.70 骨:4.72 皮膚:5.70
CAGE 大脳:0.43 小脳:- 脳幹:0.97 脳梁:- 松果体:- 末梢神経:- 脊柱:1.38 網膜:- 目:- 動脈:3.41 静脈:- リンパ節:2.11 末梢血:- 脾臓:1.52 胸腺:1.06 骨髄:- 脂肪:- 骨:1.97 皮膚:2.63
RNA-seq 大脳:0.93 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:87.20 胎盤:- 前立腺:30.90 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:17.60     肝臓:18.10        肺:100.40    膀胱:- 腎臓:56.40 下垂体:- 甲状腺:- 副腎:- 膵臓:18.80 乳腺:94.70 唾液腺:54
GeneChip 子宮:6.60 胎盤:5.40 前立腺:5.35 卵巣:5.21 精巣:4.33 心臓:4.77 骨格筋:5.66 食道:- 胃:5.82 腸:6.47 結腸:- 肝臓:7.48 肺:6.72 膀胱:6.60 腎臓:8.86 下垂体:4.64 甲状腺:- 副腎:4.50 膵臓:5.43 乳腺:6.38 唾液腺:4.40
CAGE 子宮:3.18 胎盤:1.30 前立腺:3.29 卵巣:2.11 精巣:0.99 心臓:- 骨格筋:- 食道:- 胃:2.79 腸:3.11 結腸:3.18     肝臓:4.07    肺:3.47 膀胱:3.52 腎臓:- 下垂体:1.40 甲状腺:- 副腎:1.30 膵臓:2.66 乳腺:2.81 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.02 食道:- 胃:- 腸:- 結腸:-     肝臓:5.86        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_008591
Gene ID 17295
Unigene ID Mm.86844
Probe set ID 1422990_at  [Mouse430_2]
Ensembl ID ENSMUSG00000009376

オーソログ対応遺伝子

ヒト[7]  NM_000245, NM_001127500
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1377165
1385049
1406687
1450512
1464612
1659665
1673105
1684952
1686014
2085463
2423252
2482828
2531931
2693041
2776477
2838789
3692486
3821733
7518457
7542761
7557452
7558022
7565774
7651534
7728766
7767012
7822413
7905852
7906968
7988453
8034747
8095010
8188294
8200486
8268657
8281012
8326004
8384622
8388815
8408200
8431640
8452933
8499946
8631159
8631247
8633043
8635233
8681797
8812413
8824331
8889548
8898205
8982163
8987796
9053326
9060406
9166406
9268575
9331067
9426201
9620689
9622616
9763662
10064822
10079225
10193678
10208749
10349636
10403250
10508520
10588868
10588883
10591182
10603357
10603359
10653966
10720740
10725250
10727259
10757814
10888866
10995442
11042159
11061428
11076861
11114734
11217851
11343646
11381087
11430831
11707776
11746958
11784020
11811781
11836782
11864613
12058075
12115601
12193542
12198496
12205107
12353660
12388344
12397180
12466305
12466851
12477932
12569082
12874218
12917688
12948444
14517989
14522873
14607778
14623241
14628042
14665670
14759494
14760865
15070743
15132998
15161909
15184888
15218527
15249655
15254900
15314156
15339794
15376315
15520281
15542841
15557554
15592501
15618518
15653949
15738393
15788460
15838885
15983210
16049329
16052207
16141072
16141073
16144866
16192631
16361255
16369487
16400035
16462764
16585167
16602821
16710476
16772167
16857786
16863504
16951257
16952014
17148957
17170214
17194700
17215404
17329361
17348023
17403932
17449471
17452457
17464994
17520086
17583691
17682062
17702746
17785413
17881575
17923692
17942915
17952115
18068850
18198349
18243171
18287559
18348981
18356246
18385520
18495663
18524894
18585357
18622550
18628208
18632630
18761340
18819921
18990695
19098908
19103805
19123478
19175607
19176588
19208365
19226509
19297528
19346403
19422607
19470725
19530226
19533669
19567831
19595710
19617568
19675527
19898483
20059958
20354140
20375988
20578241
20585044
20596656
20639480
20841608
20843830
20844136
20852388
20853516
20862286
20974860
20980460
21035938
21049054
21072211
21127014
21195751
21217780
21267068
21328570
21347410
21413988
21422169
21443522
21490227
21491433
21512107
21586278
21642981
21784853
21807944
21813676
21831840
21852201
22081023
22095660
22154806
22174793
22245998
22264789
22386877
22407230
22427375
22535954
22562252
22570180
22624713
22635005
22677559
22789536
22802413
22808260
22889954
22907219
22986785
22987640
23024263
23028720
23077169
23082047
23224784
23233163
23301029
23348694
23459311
23509284
23548689
23576559
23618918
23723997
23752591
23787772
23900501
23913923
23928995
23934123
23994610
24085033
24089510
24136235
24136921
24260586
24286824
24324260
24440350
24634221

遺伝子オントロジー  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0030534  adult behavior
GO:0007420  brain development
GO:0048754  branching morphogenesis of a tube
GO:0042593  glucose homeostasis
GO:0048012  hepatocyte growth factor receptor signaling pathway
GO:0001889  liver development
GO:0007275  multicellular organismal development
GO:0014812  muscle cell migration
GO:0007517  muscle organ development
GO:0051450  myoblast proliferation
GO:0014902  myotube differentiation
GO:0010801  negative regulation of peptidyl-threonine phosphorylation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0001764  neuron migration
GO:0016310  phosphorylation
GO:0001890  placenta development
GO:0050775  positive regulation of dendrite morphogenesis
GO:0045740  positive regulation of DNA replication
GO:0010628  positive regulation of gene expression
GO:0010828  positive regulation of glucose transport
GO:0045840  positive regulation of mitosis
GO:0010976  positive regulation of neuron projection development
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0010800  positive regulation of peptidyl-threonine phosphorylation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0060665  regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
GO:0060079  regulation of excitatory postsynaptic membrane potential
GO:0050804  regulation of synaptic transmission
GO:0007519  skeletal muscle tissue development
GO:0030317  sperm motility
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0009925  basal plasma membrane
GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0030425  dendrite
GO:0060076  excitatory synapse
GO:0005615  extracellular space
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0043005  neuron projection
GO:0005886  plasma membrane
GO:0014069  postsynaptic density
GO:0045211  postsynaptic membrane

Molecular Function

GO:0005524  ATP binding
GO:0008013  beta-catenin binding
GO:0005008  hepatocyte growth factor receptor activity
GO:0016301  kinase activity
GO:0000166  nucleotide binding
GO:0043548  phosphoinositide 3-kinase binding
GO:0043274  phospholipase binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0046982  protein heterodimerization activity
GO:0004672  protein kinase activity
GO:0019903  protein phosphatase binding
GO:0004713  protein tyrosine kinase activity
GO:0004872  receptor activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups
GO:0004714  transmembrane receptor protein tyrosine kinase activity