neural precursor cell expressed, developmentally down-regulated 4

同義遺伝子名

Nedd-4, mKIAA0093, Kiaa0093, AU019897, E430025J12Rik, Nedd4a, Nedd4, Nedd4-1, AL023035, E3 ubiquitin-protein ligase NEDD4, AA959633

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:1641.10

小脳:221

脳幹:-

脳梁:-

松果体:773.40

末梢神経:1165.60

脊柱:662

網膜:1671.50

目:2340.30

動脈:84.40

静脈:-

リンパ節:21.60

末梢血:301.90

脾臓:105.30

胸腺:217.40

骨髄:38.50

脂肪:-

骨:601.20

皮膚:332.50

GeneChip

大脳:11.38

小脳:11.57

脳幹:-

脳梁:-

松果体:-

末梢神経:11.74

脊柱:11.09

網膜:10.45

目:10.53

動脈:-

静脈:12.53

リンパ節:10.70

末梢血:-

脾臓:10.34

胸腺:-

骨髄:10.16

脂肪:11.81

骨:10.55

皮膚:11.35

CAGE

大脳:5.72

小脳:-

脳幹:5.70

脳梁:-

松果体:-

末梢神経:-

脊柱:5.70

網膜:-

目:-

動脈:6.57

静脈:-

リンパ節:5.31

末梢血:-

脾臓:4.94

胸腺:5.27

骨髄:-

脂肪:-

骨:5.00

皮膚:6.01

RNA-seq

大脳:28.62

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:1483.20

胎盤:607.50

前立腺:803

卵巣:459.60

精巣:709.40

心臓:576.60

骨格筋:248.60

食道:-

胃:294.60

腸:73.90

結腸:105.70

肝臓:63.40

肺:803.40

膀胱:463.30

腎臓:540

下垂体:581.30

甲状腺:112.50

副腎:-

膵臓:638

乳腺:600.70

唾液腺:162

GeneChip

子宮:12.53

胎盤:11.20

前立腺:11.87

卵巣:12.75

精巣:8.81

心臓:11.89

骨格筋:11.61

食道:-

胃:11.41

腸:10.95

結腸:-

肝臓:10.82

肺:11.68

膀胱:12.64

腎臓:11.05

下垂体:11.68

甲状腺:-

副腎:11.53

膵臓:10.37

乳腺:11.98

唾液腺:11.13

CAGE

子宮:6.57

胎盤:5.89

前立腺:5.96

卵巣:6.69

精巣:4.41

心臓:-

骨格筋:-

食道:-

胃:5.39

腸:5.11

結腸:5.24

肝臓:5.69

肺:6.06

膀胱:6.65

腎臓:-

下垂体:5.94

甲状腺:-

副腎:6.06

膵臓:6.18

乳腺:6.09

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:19.81

食道:-

胃:-

腸:-

結腸:-

肝臓:20.88

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_010890
Gene ID	17999
Unigene ID	Mm.279923
Probe set ID	1450431_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000032216

オーソログ対応遺伝子

ヒト[2]	NM_006154, NM_198400
ラット[1]	NM_012986, NM_198400

染色体

遺伝子ファミリー (Interpro ID)

IPR000008	C2 calcium-dependent membrane targeting
IPR008973	C2 calcium/lipid-binding domain, CaLB
IPR018029	C2 membrane targeting protein
IPR001202	WW/Rsp5/WWP

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0002250	adaptive immune response
GO:0048514	blood vessel morphogenesis
GO:0034644	cellular response to UV
GO:0044111	development during symbiotic interaction
GO:0003197	endocardial cushion development
GO:0042921	glucocorticoid receptor signaling pathway
GO:0007041	lysosomal transport
GO:0010766	negative regulation of sodium ion transport
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0010768	negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage
GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway
GO:0007399	nervous system development
GO:0007528	neuromuscular junction development
GO:0003151	outflow tract morphogenesis
GO:0046824	positive regulation of nucleocytoplasmic transport
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0045732	positive regulation of protein catabolic process
GO:0050847	progesterone receptor signaling pathway
GO:0070534	protein K63-linked ubiquitination
GO:0006513	protein monoubiquitination
GO:0006622	protein targeting to lysosome
GO:0016567	protein ubiquitination
GO:0042787	protein ubiquitination during ubiquitin-dependent protein catabolic process
GO:0032801	receptor catabolic process
GO:0031623	receptor internalization
GO:0048814	regulation of dendrite morphogenesis
GO:0034765	regulation of ion transmembrane transport
GO:0042391	regulation of membrane potential
GO:0050807	regulation of synapse organization
GO:0042110	T cell activation
GO:0019089	transmission of virus
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Cellular Component

GO:0005938	cell cortex
GO:0000785	chromatin
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005794	Golgi apparatus
GO:0016020	membrane
GO:0045121	membrane raft
GO:0005902	microvillus
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm
GO:0005886	plasma membrane
GO:0000151	ubiquitin ligase complex

Molecular Function

GO:0031698	beta-2 adrenergic receptor binding
GO:0016874	ligase activity
GO:0050815	phosphoserine binding
GO:0050816	phosphothreonine binding
GO:0070064	proline-rich region binding
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0019904	protein domain specific binding
GO:0070063	RNA polymerase binding
GO:0019871	sodium channel inhibitor activity
GO:0043130	ubiquitin binding
GO:0004842	ubiquitin-protein ligase activity

neural precursor cell expressed, developmentally down-regulated 4

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function