neurofibromatosis 1

詳細情報を見る

同義遺伝子名

E030030H24Rik, neurofibromin, Neurofibromin, Nf1, neurofibromatosis 1, AW494271, Nf-1, Neurofibromatosis-related protein NF-1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:52.10 小脳:55.30 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:45.60 動脈:84.40 静脈:- リンパ節:32.40 末梢血:14.40 脾臓:13.20 胸腺:19.80 骨髄:- 脂肪:- 骨:12.50 皮膚:31.70
GeneChip 大脳:6.95 小脳:6.68 脳幹:- 脳梁:- 松果体:- 末梢神経:7.24 脊柱:7.22 網膜:6.73 目:6.68 動脈:- 静脈:6.31 リンパ節:6.05 末梢血:- 脾臓:6.04 胸腺:- 骨髄:6.03 脂肪:6.48 骨:6.28 皮膚:5.83
CAGE 大脳:4.44 小脳:- 脳幹:4.64 脳梁:- 松果体:- 末梢神経:- 脊柱:4.77 網膜:- 目:- 動脈:3.92 静脈:- リンパ節:3.73 末梢血:- 脾臓:2.83 胸腺:3.14 骨髄:- 脂肪:- 骨:3.02 皮膚:3.98
RNA-seq 大脳:2.63 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:30.90 卵巣:11.50 精巣:14.80 心臓:37.20 骨格筋:- 食道:- 胃:- 腸:37 結腸:-     肝臓:-        肺:50.20    膀胱:198.50 腎臓:32.20 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:26.10 唾液腺:-
GeneChip 子宮:5.91 胎盤:5.79 前立腺:6.29 卵巣:6.15 精巣:6.56 心臓:6.45 骨格筋:6.46 食道:- 胃:5.72 腸:5.95 結腸:- 肝臓:5.84 肺:6.28 膀胱:6.26 腎臓:6.08 下垂体:6.58 甲状腺:- 副腎:6.48 膵臓:6.41 乳腺:6.16 唾液腺:5.93
CAGE 子宮:3.71 胎盤:2.89 前立腺:4.00 卵巣:3.83 精巣:4.73 心臓:- 骨格筋:- 食道:- 胃:2.44 腸:3.42 結腸:3.68     肝臓:3.20    肺:3.76 膀胱:3.77 腎臓:- 下垂体:4.02 甲状腺:- 副腎:3.86 膵臓:3.64 乳腺:3.52 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.76 食道:- 胃:- 腸:- 結腸:-     肝臓:1.98        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_010897
Gene ID 18015
Unigene ID Mm.255596
Probe set ID 1438067_at  [Mouse430_2]
Ensembl ID ENSMUSG00000020716

オーソログ対応遺伝子

ヒト[14]  NM_000267, NM_001042492, NM_001128147
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1946382
2169593
3925999
7474134
7477259
7490078
7557995
7568895
7594550
7609078
7626882
7633452
7650394
7671302
7920653
7926784
7958951
7959746
7977656
8026534
8036002
8306889
8314000
8353485
8563750
8566965
8585954
8622964
8808709
8812413
8884266
8889548
8889551
8982467
9001241
9054942
9177778
9214616
9307024
9405660
9434953
9434955
9524273
9608530
9778496
9796699
9804998
9852579
9878702
9917000
10339466
10349636
10383727
10392751
10419687
10442636
10498620
10557097
10586246
10591652
10591653
10594763
10620616
10678181
10725249
10844550
10845775
10862698
10945472
10973261
11042159
11076861
11217851
11237520
11246230
11279521
11297510
11306621
11401406
11407944
11425624
11435472
11544276
11751683
11788835
11793011
11858825
11988578
12077339
12082543
12118376
12154062
12386807
12393498
12393709
12409258
12417644
12427839
12466851
12469121
12520002
12573431
12600938
12696059
12881715
12904481
14502561
14523097
14610273
14679180
14695164
14724565
14739366
14982883
15039234
15125795
15133494
15319471
15371411
15622533
15652750
15665300
15778374
15804420
15805275
15886874
15937108
15944386
15999204
16093333
16098465
16141072
16141073
16180234
16226708
16267007
16271875
16288202
16298082
16314489
16397217
16405917
16512683
16525748
16602821
16644864
16648142
16651634
16835260
16893911
16906226
16944949
16959763
17053831
17090653
17096025
17114649
17141628
17208258
17216419
17236191
17241271
17274974
17277161
17314307
17317783
17348023
17383899
17510408
17582688
17875698
17967772
18089636
18089649
18164202
18213578
18218617
18242511
18242512
18242513
18272679
18316617
18329113
18335562
18371380
18383150
18442999
18451155
18477655
18614404
18614544
18768391
18948576
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18984165
19056885
19074905
19076778
19111880
19191334
19228926
19243017
19247213
19347398
19414599
19427294
19475561
19477430
19479903
19525901
19573811
19574548
19661150
19710506
19727076
19757398
19846776
19892785
20124472
20154697
20160346
20200958
20209053
20233966
20233971
20307317
20410111
20551058
20571392
20600672
20624961
20826448
20876733
21037083
21170735
21199799
21233129
21267068
21270437
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21439418
21467166
21478499
21501659
21551249
21551250
21555464
21642990
21677750
21681782
21737130
21748792
21757497
21896734
21903164
21907929
21931722
21963652
21980365
22105171
22118770
22160242
22234937
22260870
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22399775
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22700876
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22789544
22810304
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22854781
22868293
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23071067
23144792
23171796
23197650
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23434321
23522726
23528211
23555837
23571107
23578956
23729642
23762458
23863460
23869022
24035394
24067356
24075988
24163128
24211110
24755485

遺伝子オントロジー  (GO ID)

Biological Process

GO:0030036  actin cytoskeleton organization
GO:0030325  adrenal gland development
GO:0048844  artery morphogenesis
GO:0007420  brain development
GO:0048593  camera-type eye morphogenesis
GO:0007154  cell communication
GO:0021987  cerebral cortex development
GO:0050890  cognition
GO:0030199  collagen fibril organization
GO:0030198  extracellular matrix organization
GO:0021897  forebrain astrocyte development
GO:0048853  forebrain morphogenesis
GO:0007507  heart development
GO:0008625  induction of apoptosis via death domain receptors
GO:0001889  liver development
GO:0000165  MAPKKK cascade
GO:0001656  metanephros development
GO:0022011  myelination in the peripheral nervous system
GO:0016525  negative regulation of angiogenesis
GO:0048712  negative regulation of astrocyte differentiation
GO:0030336  negative regulation of cell migration
GO:0008285  negative regulation of cell proliferation
GO:0001953  negative regulation of cell-matrix adhesion
GO:0001937  negative regulation of endothelial cell proliferation
GO:0048147  negative regulation of fibroblast proliferation
GO:0043407  negative regulation of MAP kinase activity
GO:0043409  negative regulation of MAPKKK cascade
GO:0007406  negative regulation of neuroblast proliferation
GO:0046929  negative regulation of neurotransmitter secretion
GO:0048715  negative regulation of oligodendrocyte differentiation
GO:0045671  negative regulation of osteoclast differentiation
GO:0006469  negative regulation of protein kinase activity
GO:0035021  negative regulation of Rac protein signal transduction
GO:0046580  negative regulation of Ras protein signal transduction
GO:0042992  negative regulation of transcription factor import into nucleus
GO:0021915  neural tube development
GO:0001649  osteoblast differentiation
GO:0007422  peripheral nervous system development
GO:0014065  phosphoinositide 3-kinase cascade
GO:0043473  pigmentation
GO:0045762  positive regulation of adenylate cyclase activity
GO:0043065  positive regulation of apoptosis
GO:0001938  positive regulation of endothelial cell proliferation
GO:0043525  positive regulation of neuron apoptosis
GO:0032320  positive regulation of Ras GTPase activity
GO:0007265  Ras protein signal transduction
GO:0045765  regulation of angiogenesis
GO:0043535  regulation of blood vessel endothelial cell migration
GO:0045124  regulation of bone resorption
GO:0042127  regulation of cell proliferation
GO:0001952  regulation of cell-matrix adhesion
GO:0045685  regulation of glial cell differentiation
GO:0048169  regulation of long-term neuronal synaptic plasticity
GO:0045664  regulation of neuron differentiation
GO:0032318  regulation of Ras GTPase activity
GO:0051056  regulation of small GTPase mediated signal transduction
GO:0032228  regulation of synaptic transmission, GABAergic
GO:0001666  response to hypoxia
GO:0014044  Schwann cell development
GO:0007165  signal transduction
GO:0007519  skeletal muscle tissue development
GO:0048745  smooth muscle tissue development
GO:0021510  spinal cord development
GO:0048485  sympathetic nervous system development
GO:0008542  visual learning
GO:0042060  wound healing

Cellular Component

GO:0030424  axon
GO:0005737  cytoplasm
GO:0030425  dendrite
GO:0005622  intracellular
GO:0031235  intrinsic to internal side of plasma membrane
GO:0016020  membrane
GO:0043005  neuron projection
GO:0005634  nucleus
GO:0014069  postsynaptic density
GO:0043234  protein complex

Molecular Function

GO:0005096  GTPase activator activity
GO:0008017  microtubule binding
GO:0005515  protein binding
GO:0005099  Ras GTPase activator activity
GO:0045545  syndecan binding