nitric oxide synthase 3, endothelial cell

同義遺伝子名

Constitutive NOS, NOS type III, Nos-3, nitric oxide synthase 3, endothelial cell, eNOS, ecNOS, Ecnos, Nos3, Endothelial NOS, EC-NOS, NOSIII, 2310065A03Rik, Nitric-oxide synthase, endothelial, cNOS

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:19.10

小脳:55.30

脳幹:-

脳梁:-

松果体:-

末梢神経:38.20

脊柱:-

網膜:-

目:7.60

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:79

胸腺:-

骨髄:-

脂肪:-

骨:12.50

皮膚:-

GeneChip

大脳:6.86

小脳:6.59

脳幹:-

脳梁:-

松果体:-

末梢神経:6.78

脊柱:7

網膜:5.78

目:5.84

動脈:-

静脈:6.91

リンパ節:7.17

末梢血:-

脾臓:6.74

胸腺:-

骨髄:5.27

脂肪:8.81

骨:5.79

皮膚:6.51

CAGE

大脳:2.15

小脳:-

脳幹:2.52

脳梁:-

松果体:-

末梢神経:-

脊柱:2.58

網膜:-

目:-

動脈:3.77

静脈:-

リンパ節:1.98

末梢血:-

脾臓:1.78

胸腺:0.82

骨髄:-

脂肪:-

骨:1.51

皮膚:2.52

RNA-seq

大脳:2.27

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:14.80

心臓:18.60

骨格筋:-

食道:-

胃:-

腸:-

結腸:17.60

肝臓:-

肺:10

膀胱:-

腎臓:-

下垂体:116.30

甲状腺:-

副腎:-

膵臓:-

乳腺:16.30

唾液腺:-

GeneChip

子宮:7.25

胎盤:6.04

前立腺:6

卵巣:7.86

精巣:6.97

心臓:9.12

骨格筋:8.06

食道:-

胃:6.31

腸:5.98

結腸:-

肝臓:6.74

肺:7.93

膀胱:6.47

腎臓:6.80

下垂体:7.13

甲状腺:-

副腎:8.08

膵臓:6.89

乳腺:7.84

唾液腺:6.10

CAGE

子宮:2.22

胎盤:1.60

前立腺:1.41

卵巣:2.58

精巣:0

心臓:-

骨格筋:-

食道:-

胃:1.75

腸:1.60

結腸:1.19

肝臓:2.02

肺:3.08

膀胱:2.12

腎臓:-

下垂体:1.40

甲状腺:-

副腎:2.53

膵臓:1.61

乳腺:2.23

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:2.42

食道:-

胃:-

腸:-

結腸:-

肝臓:1.50

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_008713
Gene ID	18127
Unigene ID	Mm.258415
Probe set ID	1422622_at [Mouse430_2]
Ensembl ID	ENSMUSG00000028978

オーソログ対応遺伝子

ヒト[4]	NM_000603, NM_001160109, NM_001160110, NM_001160111
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR001094	Flavodoxin-like
IPR008254	Flavodoxin/nitric oxide synthase
IPR001709	Flavoprotein pyridine nucleotide cytochrome reductase

Link to Pubmed (Pubmed ID)

7479866
7518615
7539311
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8667023
8702423
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24485922
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24643960

遺伝子オントロジー (GO ID)

Biological Process

GO:0001525	angiogenesis
GO:0006527	arginine catabolic process
GO:0001974	blood vessel remodeling
GO:0071260	cellular response to mechanical stimulus
GO:0043542	endothelial cell migration
GO:0001701	in utero embryonic development
GO:0031663	lipopolysaccharide-mediated signaling pathway
GO:0030324	lung development
GO:0045776	negative regulation of blood pressure
GO:0051926	negative regulation of calcium ion transport
GO:0008285	negative regulation of cell proliferation
GO:0051346	negative regulation of hydrolase activity
GO:0014740	negative regulation of muscle hyperplasia
GO:0043267	negative regulation of potassium ion transport
GO:0048662	negative regulation of smooth muscle cell proliferation
GO:0006809	nitric oxide biosynthetic process
GO:0007263	nitric oxide mediated signal transduction
GO:0001542	ovulation from ovarian follicle
GO:0055114	oxidation reduction
GO:0045766	positive regulation of angiogenesis
GO:0043065	positive regulation of apoptosis
GO:0031284	positive regulation of guanylate cyclase activity
GO:0045909	positive regulation of vasodilation
GO:0050880	regulation of blood vessel size
GO:0002028	regulation of sodium ion transport
GO:0003100	regulation of systemic arterial blood pressure by endothelin
GO:0003057	regulation of the force of heart contraction by chemical signal
GO:0032355	response to estradiol stimulus
GO:0007165	signal transduction
GO:0014806	smooth muscle hyperplasia

Cellular Component

GO:0045177	apical part of cell
GO:0005901	caveola
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005829	cytosol
GO:0005794	Golgi apparatus
GO:0016020	membrane
GO:0005739	mitochondrion
GO:0005730	nucleolus
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0012506	vesicle membrane

Molecular Function

GO:0003785	actin monomer binding
GO:0034618	arginine binding
GO:0005516	calmodulin binding
GO:0050660	FAD binding
GO:0010181	FMN binding
GO:0020037	heme binding
GO:0051879	Hsp90 protein binding
GO:0005506	iron ion binding
GO:0046872	metal ion binding
GO:0050661	NADP or NADPH binding
GO:0003958	NADPH-hemoprotein reductase activity
GO:0004517	nitric-oxide synthase activity
GO:0016491	oxidoreductase activity
GO:0034617	tetrahydrobiopterin binding

nitric oxide synthase 3, endothelial cell

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function