protein kinase C, alpha

詳細情報を見る

同義遺伝子名

PKC-A, protein kinase C, alpha, Pkca, Protein kinase C alpha type, PKC-alpha, Prkca

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:88.60 小脳:36.80 脳幹:63.60 脳梁:- 松果体:- 末梢神経:57.30 脊柱:47.30 網膜:64.30 目:68.40 動脈:- 静脈:- リンパ節:10.80 末梢血:215.70 脾臓:- 胸腺:49.40 骨髄:- 脂肪:- 骨:50.10 皮膚:23.80
GeneChip 大脳:5.44 小脳:5.04 脳幹:- 脳梁:- 松果体:- 末梢神経:6.51 脊柱:5.26 網膜:5.15 目:5.24 動脈:- 静脈:4.82 リンパ節:4.87 末梢血:- 脾臓:4.68 胸腺:- 骨髄:5.54 脂肪:4.88 骨:4.95 皮膚:4.47
CAGE 大脳:4.21 小脳:- 脳幹:3.82 脳梁:- 松果体:- 末梢神経:- 脊柱:4.06 網膜:- 目:- 動脈:2.99 静脈:- リンパ節:4.33 末梢血:- 脾臓:3.34 胸腺:3.72 骨髄:- 脂肪:- 骨:3.62 皮膚:3.98
RNA-seq 大脳:9.28 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:43.60 胎盤:- 前立腺:61.80 卵巣:- 精巣:- 心臓:55.80 骨格筋:71 食道:- 胃:- 腸:- 結腸:17.60     肝臓:36.20        肺:30.10    膀胱:- 腎臓:56.40 下垂体:25.80 甲状腺:- 副腎:- 膵臓:93.80 乳腺:49 唾液腺:-
GeneChip 子宮:4.83 胎盤:4.99 前立腺:4.71 卵巣:4.47 精巣:4.83 心臓:5.67 骨格筋:6.01 食道:- 胃:5.40 腸:6.20 結腸:- 肝臓:4.89 肺:4.48 膀胱:4.91 腎臓:5.18 下垂体:4.99 甲状腺:- 副腎:4.49 膵臓:4.62 乳腺:5.03 唾液腺:4.52
CAGE 子宮:2.98 胎盤:2.36 前立腺:4.88 卵巣:2.90 精巣:2.05 心臓:- 骨格筋:- 食道:- 胃:2.73 腸:4.57 結腸:4.62     肝臓:2.68    肺:3.81 膀胱:3.80 腎臓:- 下垂体:3.68 甲状腺:- 副腎:2.18 膵臓:2.83 乳腺:2.06 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:3.16 食道:- 胃:- 腸:- 結腸:-     肝臓:2.07        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_011101
Gene ID 18750
Unigene ID Mm.222178
Probe set ID 1427562_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000050965

オーソログ対応遺伝子

ヒト[4]  NM_002737
ラット[1]  NM_001105713

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1302014
1427919
2469625
2567264
2590242
2601739
7507077
7509775
7513693
7590247
7606770
7648400
7741753
7760054
7767000
7789972
7835084
7844141
7873880
7920028
7963691
7972137
7985811
7987836
8234252
8251184
8282096
8288233
8589532
8630490
8661048
8672127
8700543
8717055
8827514
8889548
8922669
8948582
9011744
9196007
9242710
9321482
9344654
9367786
9441749
9457688
9486851
9508782
9653646
9657272
9806850
9854032
10337632
10349636
10391924
10486248
10504298
10813773
10841548
10879655
10882525
10926556
11042159
11076861
11156601
11217851
11477572
11493566
11668067
11923480
11940581
12000751
12006349
12031982
12067706
12095674
12095983
12112008
12115694
12149272
12355443
12466851
12477932
12533605
12618484
12643789
12704190
12761849
12782152
12794082
12826667
12928424
12970181
14519497
14605019
14610273
14613966
14627629
14681479
14966364
14966518
14998930
15006698
15039142
15051735
15147297
15184055
15226823
15229137
15262987
15277392
15314167
15363390
15363391
15367584
15375180
15448167
15456937
15540248
15579573
15590069
15661932
15775979
15797020
15814724
15911881
16014375
16040001
16055440
16079140
16103087
16115026
16141072
16141073
16182275
16183862
16303847
16343477
16430878
16484320
16512683
16515554
16537572
16585392
16602821
16620963
16651659
16670309
16702404
16707110
16735462
16751397
16814779
16849539
16880328
16899228
16955103
16959241
16962988
16979586
17016558
17050694
17092954
17114649
17149706
17251443
17347670
17367165
17424843
17480014
17495347
17506942
17553429
17610064
17628588
17644814
17650117
17765678
17921332
17922342
17936705
17956267
18032449
18094249
18188456
18198336
18265009
18279309
18292949
18308476
18313852
18354190
18387001
18418732
18460603
18535104
18566587
18621733
18655205
18722532
18778700
18799693
18832165
18851840
18940586
18955497
19029199
19056838
19060919
19066285
19071120
19081073
19096028
19100728
19111595
19117954
19130990
19147498
19147982
19230851
19239004
19279690
19300477
19356803
19358334
19369415
19458061
19556521
19580852
19581409
19596361
19680541
19693771
19710177
19740326
19801662
19846755
19910703
19914171
19939451
19945391
19950169
19966277
20053794
20093473
20107170
20151282
20175913
20237998
20385812
20392936
20417251
20419132
20463215
20500675
20505191
20513439
20554612
20571823
20643355
20691662
20815813
20826655
20875817
20889505
20940303
20951242
20962046
21048081
21087508
21094527
21138975
21177258
21190563
21232169
21238928
21303848
21307321
21321125
21419781
21454537
21473788
21478884
21527521
21540297
21550664
21558380
21570469
21596041
21606200
21642422
21658591
21705673
21756219
21782794
21835343
21880782
21888435
21903076
21903576
21940450
21957166
21976518
22031545
22031842
22132835
22171059
22188405
22258620
22265677
22271577
22281059
22301620
22318721
22407785
22492943
22531726
22566700
22609278
22689267
22706318
22798526
22819675
22832728
22843879
22913772
22962432
22993418
23001562
23028752
23035091
23066026
23070544
23097465
23144896
23172916
23197712
23236519
23239877
23290522
23301081
23386589
23434935
23439007
23479264
23487309
23525101
23604119
23626468
23630435
23709216
23714736
23824069
23863479
23887639
23908466
23926259
23932931
24151077
24153433
24219286
24333658
24338818
24478091
24493668

遺伝子オントロジー  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0006915  apoptosis
GO:0007155  cell adhesion
GO:0006874  cellular calcium ion homeostasis
GO:0071322  cellular response to carbohydrate stimulus
GO:0021955  central nervous system neuron axonogenesis
GO:0002062  chondrocyte differentiation
GO:0000188  inactivation of MAPK activity
GO:0050930  induction of positive chemotaxis
GO:0007611  learning or memory
GO:0008285  negative regulation of cell proliferation
GO:0034351  negative regulation of glial cell apoptosis
GO:0046325  negative regulation of glucose import
GO:0045822  negative regulation of heart contraction
GO:0046627  negative regulation of insulin receptor signaling pathway
GO:0001933  negative regulation of protein amino acid phosphorylation
GO:0006469  negative regulation of protein kinase activity
GO:0017148  negative regulation of translation
GO:0030593  neutrophil chemotaxis
GO:0018105  peptidyl-serine phosphorylation
GO:0018107  peptidyl-threonine phosphorylation
GO:0016310  phosphorylation
GO:0045766  positive regulation of angiogenesis
GO:0043536  positive regulation of blood vessel endothelial cell migration
GO:0010613  positive regulation of cardiac muscle hypertrophy
GO:0045785  positive regulation of cell adhesion
GO:0010595  positive regulation of endothelial cell migration
GO:0001938  positive regulation of endothelial cell proliferation
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0045921  positive regulation of exocytosis
GO:0050729  positive regulation of inflammatory response
GO:0031666  positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0045651  positive regulation of macrophage differentiation
GO:0045931  positive regulation of mitotic cell cycle
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0051965  positive regulation of synaptogenesis
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0006937  regulation of muscle contraction
GO:0050730  regulation of peptidyl-tyrosine phosphorylation
GO:0048259  regulation of receptor-mediated endocytosis
GO:0002026  regulation of the force of heart contraction
GO:0032355  response to estradiol stimulus
GO:0045471  response to ethanol
GO:0070555  response to interleukin-1
GO:0000302  response to reactive oxygen species

Cellular Component

GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0030425  dendrite
GO:0005783  endoplasmic reticulum
GO:0016020  membrane
GO:0045121  membrane raft
GO:0005739  mitochondrion
GO:0043005  neuron projection
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0001750  photoreceptor outer segment
GO:0005886  plasma membrane
GO:0043234  protein complex

Molecular Function

GO:0005524  ATP binding
GO:0004698  calcium-dependent protein kinase C activity
GO:0019899  enzyme binding
GO:0016301  kinase activity
GO:0046872  metal ion binding
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0004697  protein kinase C activity
GO:0004674  protein serine/threonine kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups
GO:0008270  zinc ion binding