protein kinase C, alpha

詳細情報を見る

同義遺伝子名

PKC-A, protein kinase C, alpha, Pkca, Protein kinase C alpha type, PKC-alpha, Prkca

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:88.60

小脳:36.80

脳幹:63.60

脳梁:-

松果体:-

末梢神経:57.30

脊柱:47.30

網膜:64.30

目:68.40

動脈:-

静脈:-

リンパ節:10.80

末梢血:215.70

脾臓:-

胸腺:49.40

骨髄:-

脂肪:-

骨:50.10

皮膚:23.80

GeneChip

大脳:7.45

小脳:6.44

脳幹:-

脳梁:-

松果体:-

末梢神経:8.85

脊柱:6.91

網膜:7.27

目:6.65

動脈:-

静脈:6.66

リンパ節:6.69

末梢血:-

脾臓:6.70

胸腺:-

骨髄:7.81

脂肪:6.23

骨:7.62

皮膚:5.50

CAGE

大脳:4.21

小脳:-

脳幹:3.82

脳梁:-

松果体:-

末梢神経:-

脊柱:4.06

網膜:-

目:-

動脈:2.99

静脈:-

リンパ節:4.33

末梢血:-

脾臓:3.34

胸腺:3.72

骨髄:-

脂肪:-

骨:3.62

皮膚:3.98

RNA-seq

大脳:9.28

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:43.60

胎盤:-

前立腺:61.80

卵巣:-

精巣:-

心臓:55.80

骨格筋:71

食道:-

胃:-

腸:-

結腸:17.60

肝臓:36.20

肺:30.10

膀胱:-

腎臓:56.40

下垂体:25.80

甲状腺:-

副腎:-

膵臓:93.80

乳腺:49

唾液腺:-

GeneChip

子宮:5.45

胎盤:5.77

前立腺:7.23

卵巣:5.94

精巣:5.02

心臓:7.68

骨格筋:8.54

食道:-

胃:7.40

腸:8.65

結腸:-

肝臓:5.71

肺:6.79

膀胱:7.16

腎臓:6.16

下垂体:7.22

甲状腺:-

副腎:5.05

膵臓:5.83

乳腺:6.66

唾液腺:5.78

CAGE

子宮:2.98

胎盤:2.36

前立腺:4.88

卵巣:2.90

精巣:2.05

心臓:-

骨格筋:-

食道:-

胃:2.73

腸:4.57

結腸:4.62

肝臓:2.68

肺:3.81

膀胱:3.80

腎臓:-

下垂体:3.68

甲状腺:-

副腎:2.18

膵臓:2.83

乳腺:2.06

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:3.16

食道:-

胃:-

腸:-

結腸:-

肝臓:2.07

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_011101
Gene ID	18750
Unigene ID	Mm.222178
Probe set ID	1450945_at [Mouse430_2]
Ensembl ID	ENSMUSG00000050965

オーソログ対応遺伝子

ヒト[4]	NM_002737
ラット[1]	NM_001105713

染色体

遺伝子ファミリー (Interpro ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0001525	angiogenesis
GO:0006915	apoptosis
GO:0007155	cell adhesion
GO:0006874	cellular calcium ion homeostasis
GO:0071322	cellular response to carbohydrate stimulus
GO:0021955	central nervous system neuron axonogenesis
GO:0002062	chondrocyte differentiation
GO:0000188	inactivation of MAPK activity
GO:0050930	induction of positive chemotaxis
GO:0007611	learning or memory
GO:0008285	negative regulation of cell proliferation
GO:0034351	negative regulation of glial cell apoptosis
GO:0046325	negative regulation of glucose import
GO:0045822	negative regulation of heart contraction
GO:0046627	negative regulation of insulin receptor signaling pathway
GO:0001933	negative regulation of protein amino acid phosphorylation
GO:0006469	negative regulation of protein kinase activity
GO:0017148	negative regulation of translation
GO:0030593	neutrophil chemotaxis
GO:0018105	peptidyl-serine phosphorylation
GO:0018107	peptidyl-threonine phosphorylation
GO:0016310	phosphorylation
GO:0045766	positive regulation of angiogenesis
GO:0043536	positive regulation of blood vessel endothelial cell migration
GO:0010613	positive regulation of cardiac muscle hypertrophy
GO:0045785	positive regulation of cell adhesion
GO:0010595	positive regulation of endothelial cell migration
GO:0001938	positive regulation of endothelial cell proliferation
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0045921	positive regulation of exocytosis
GO:0050729	positive regulation of inflammatory response
GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0045651	positive regulation of macrophage differentiation
GO:0045931	positive regulation of mitotic cell cycle
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0051965	positive regulation of synaptogenesis
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0006937	regulation of muscle contraction
GO:0050730	regulation of peptidyl-tyrosine phosphorylation
GO:0048259	regulation of receptor-mediated endocytosis
GO:0002026	regulation of the force of heart contraction
GO:0032355	response to estradiol stimulus
GO:0045471	response to ethanol
GO:0070555	response to interleukin-1
GO:0000302	response to reactive oxygen species

Cellular Component

GO:0043025	cell soma
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0030425	dendrite
GO:0005783	endoplasmic reticulum
GO:0016020	membrane
GO:0045121	membrane raft
GO:0005739	mitochondrion
GO:0043005	neuron projection
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm
GO:0001750	photoreceptor outer segment
GO:0005886	plasma membrane
GO:0043234	protein complex

Molecular Function

GO:0005524	ATP binding
GO:0004698	calcium-dependent protein kinase C activity
GO:0019899	enzyme binding
GO:0016301	kinase activity
GO:0046872	metal ion binding
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0004697	protein kinase C activity
GO:0004674	protein serine/threonine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0008270	zinc ion binding

IPR000961	AGC-kinase, C-terminal
IPR000008	C2 calcium-dependent membrane targeting
IPR008973	C2 calcium/lipid-binding domain, CaLB
IPR018029	C2 membrane targeting protein
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

protein kinase C, alpha

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function