polo-like kinase 1 (Drosophila)

同義遺伝子名

PLK-1, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, Plk1, Serine/threonine-protein kinase 13, polo-like kinase 1 (Drosophila), Plk, STPK13

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:60.80

小脳:55.30

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:141.90

網膜:225

目:152

動脈:-

静脈:-

リンパ節:10.80

末梢血:57.50

脾臓:65.80

胸腺:79

骨髄:-

脂肪:-

骨:162.80

皮膚:63.30

GeneChip

大脳:5.50

小脳:5.58

脳幹:-

脳梁:-

松果体:-

末梢神経:5.52

脊柱:5.65

網膜:5.75

目:5.91

動脈:-

静脈:7.12

リンパ節:7.32

末梢血:-

脾臓:7.28

胸腺:-

骨髄:10.15

脂肪:5.86

骨:9.15

皮膚:6.25

CAGE

大脳:0.10

小脳:-

脳幹:0.09

脳梁:-

松果体:-

末梢神経:-

脊柱:0.17

網膜:-

目:-

動脈:0.54

静脈:-

リンパ節:1.64

末梢血:-

脾臓:4.02

胸腺:3.11

骨髄:-

脂肪:-

骨:3.46

皮膚:1.70

RNA-seq

大脳:0.94

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:43.60

胎盤:13.80

前立腺:-

卵巣:229.80

精巣:147.80

心臓:55.80

骨格筋:-

食道:-

胃:130.90

腸:37

結腸:70.50

肝臓:36.20

肺:30.10

膀胱:66.20

腎臓:16.10

下垂体:116.30

甲状腺:-

副腎:-

膵臓:28.10

乳腺:84.90

唾液腺:-

GeneChip

子宮:6.99

胎盤:5.96

前立腺:5.88

卵巣:7.18

精巣:9.92

心臓:5.78

骨格筋:5.83

食道:-

胃:7.52

腸:8.26

結腸:-

肝臓:5.67

肺:5.33

膀胱:5.57

腎臓:5.73

下垂体:5.75

甲状腺:-

副腎:5.28

膵臓:6.57

乳腺:6.45

唾液腺:5.65

CAGE

子宮:1.58

胎盤:1.82

前立腺:0.74

卵巣:1.98

精巣:5.12

心臓:-

骨格筋:-

食道:-

胃:1.07

腸:2.96

結腸:2.69

肝臓:0.26

肺:1.22

膀胱:0.18

腎臓:-

下垂体:0

甲状腺:-

副腎:0.64

膵臓:0.84

乳腺:2.02

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:0.44

食道:-

胃:-

腸:-

結腸:-

肝臓:0

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_011121
Gene ID	18817
Unigene ID	Mm.16525
Probe set ID	1448191_at [Mouse430_2]
Ensembl ID	ENSMUSG00000030867

オーソログ対応遺伝子

ヒト[1]	NM_005030
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0007092	activation of anaphase-promoting complex activity during mitotic cell cycle
GO:0007049	cell cycle
GO:0051301	cell division
GO:0051297	centrosome organization
GO:0000910	cytokinesis
GO:0031572	G2/M transition DNA damage checkpoint
GO:0000086	G2/M transition of mitotic cell cycle
GO:0001578	microtubule bundle formation
GO:0007067	mitosis
GO:0007094	mitotic cell cycle spindle assembly checkpoint
GO:0000236	mitotic prometaphase
GO:0000070	mitotic sister chromatid segregation
GO:0043066	negative regulation of apoptosis
GO:0045736	negative regulation of cyclin-dependent protein kinase activity
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0018105	peptidyl-serine phosphorylation
GO:0016310	phosphorylation
GO:0040038	polar body extrusion after meiotic divisions
GO:0010800	positive regulation of peptidyl-threonine phosphorylation
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0045862	positive regulation of proteolysis
GO:0051443	positive regulation of ubiquitin-protein ligase activity
GO:0006468	protein amino acid phosphorylation
GO:0031648	protein destabilization
GO:0071168	protein localization to chromatin
GO:0016567	protein ubiquitination
GO:0007346	regulation of mitotic cell cycle
GO:0030071	regulation of mitotic metaphase/anaphase transition
GO:0043393	regulation of protein binding

Cellular Component

GO:0005813	centrosome
GO:0005694	chromosome
GO:0000775	chromosome, centromeric region
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0000776	kinetochore
GO:0030496	midbody
GO:0005634	nucleus
GO:0000942	outer kinetochore of condensed nuclear chromosome
GO:0005819	spindle
GO:0005876	spindle microtubule
GO:0051233	spindle midzone
GO:0000922	spindle pole

Molecular Function

GO:0010997	anaphase-promoting complex binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0008017	microtubule binding
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0019901	protein kinase binding
GO:0004674	protein serine/threonine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

polo-like kinase 1 (Drosophila)

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function