POU domain, class 5, transcription factor 1

詳細情報を見る

同義遺伝子名

Otf3-rs7, Oct3/4, Otf-4, Oct-3, Oct-3/4, POU domain, class 5, transcription factor 1, NF-A3, Otf4, Oct3, Oct-4, Octamer-binding transcription factor 3, Oct4, Otf3, Otf3g, Otf-3, Pou5f1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:64.30 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:15.80
GeneChip 大脳:4.41 小脳:4.55 脳幹:- 脳梁:- 松果体:- 末梢神経:4.76 脊柱:4.44 網膜:4.85 目:4.79 動脈:- 静脈:4.34 リンパ節:4.39 末梢血:- 脾臓:4.56 胸腺:- 骨髄:4.45 脂肪:4.59 骨:4.55 皮膚:4.52
CAGE 大脳:0 小脳:- 脳幹:0 脳梁:- 松果体:- 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0 静脈:- リンパ節:0 末梢血:- 脾臓:0 胸腺:0.27 骨髄:- 脂肪:- 骨:0 皮膚:0
RNA-seq nodata
EST 子宮:- 胎盤:- 前立腺:- 卵巣:57.50 精巣:7.40 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:4.34 胎盤:4.43 前立腺:4.49 卵巣:4.78 精巣:5.47 心臓:4.49 骨格筋:4.59 食道:- 胃:4.54 腸:4.66 結腸:- 肝臓:4.74 肺:4.28 膀胱:4.44 腎臓:4.61 下垂体:4.58 甲状腺:- 副腎:4.61 膵臓:4.87 乳腺:4.58 唾液腺:4.34
CAGE 子宮:0 胎盤:0 前立腺:0 卵巣:0.69 精巣:0.45 心臓:- 骨格筋:- 食道:- 胃:0 腸:0 結腸:0     肝臓:0    肺:0 膀胱:0 腎臓:- 下垂体:0 甲状腺:- 副腎:0 膵臓:0 乳腺:0 唾液腺:-
RNA-seq nodata

IDs

Refseq ID NM_013633
Gene ID 18999
Unigene ID Mm.17031
Probe set ID 1417945_at  [Mouse430_2]
Ensembl ID ENSMUSG00000024406

オーソログ対応遺伝子

ヒト[9]  NM_001173531, NM_002701, NM_203289, NM_001159542
ラット[9]  NM_001173531, NM_002701, NM_203289, NM_001159542

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1408763
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0003130  BMP signaling pathway involved in heart induction
GO:0060913  cardiac cell fate determination
GO:0045165  cell fate commitment
GO:0060795  cell fate commitment involved in the formation of primary germ layers
GO:0001712  ectodermal cell fate commitment
GO:0001711  endodermal cell fate commitment
GO:0001714  endodermal cell fate specification
GO:0030718  germ-line stem cell maintenance
GO:0001710  mesodermal cell fate commitment
GO:0042789  mRNA transcription from RNA polymerase II promoter
GO:0007275  multicellular organismal development
GO:0045955  negative regulation of calcium ion-dependent exocytosis
GO:0045596  negative regulation of cell differentiation
GO:0060965  negative regulation of gene silencing by miRNA
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0060391  positive regulation of SMAD protein nuclear translocation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0090081  regulation of canonical Wnt receptor signaling pathway involved in heart induction
GO:0010468  regulation of gene expression
GO:0006355  regulation of transcription, DNA-dependent
GO:0010033  response to organic substance
GO:0032526  response to retinoic acid
GO:0035019  somatic stem cell maintenance
GO:0048863  stem cell differentiation
GO:0019827  stem cell maintenance
GO:0006366  transcription from RNA polymerase II promoter
GO:0006351  transcription, DNA-dependent
GO:0001829  trophectodermal cell differentiation

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0005667  transcription factor complex
GO:0017053  transcriptional repressor complex

Molecular Function

GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0035198  miRNA binding
GO:0070974  POU domain binding
GO:0005515  protein binding
GO:0043565  sequence-specific DNA binding
GO:0003714  transcription corepressor activity
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding
GO:0031625  ubiquitin protein ligase binding