peroxisome proliferator activated receptor alpha

 詳細情報を見る

同義遺伝子名

PPAR-alpha, Ppara, Peroxisome proliferator-activated receptor alpha, PPAR, PPARalpha, Nr1c1, peroxisome proliferator activated receptor alpha, Ppar

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:6.90 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:76.40 脊柱:- 網膜:- 目:22.80 動脈:843.90 静脈:- リンパ節:- 末梢血:14.40 脾臓:13.20 胸腺:- 骨髄:- 脂肪:- 骨:12.50 皮膚:15.80
GeneChip 大脳:5.34 小脳:5.21 脳幹:- 脳梁:- 松果体:- 末梢神経:5.57 脊柱:5.08 網膜:7.12 目:5.73 動脈:- 静脈:5.14 リンパ節:4.99 末梢血:- 脾臓:4.74 胸腺:- 骨髄:4.75 脂肪:8.46 骨:4.94 皮膚:6.49
CAGE 大脳:0.49 小脳:- 脳幹:0.94 脳梁:- 松果体:- 末梢神経:- 脊柱:0.66 網膜:- 目:- 動脈:4.92 静脈:- リンパ節:0.23 末梢血:- 脾臓:0 胸腺:0.67 骨髄:- 脂肪:- 骨:1.51 皮膚:1.81
RNA-seq 大脳:1.15 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:- 前立腺:- 卵巣:11.50 精巣:14.80 心臓:18.60 骨格筋:35.50 食道:- 胃:- 腸:- 結腸:17.60     肝臓:235.30        肺:-    膀胱:132.40 腎臓:104.80 下垂体:- 甲状腺:- 副腎:- 膵臓:9.40 乳腺:13.10 唾液腺:-
GeneChip 子宮:5.13 胎盤:4.95 前立腺:5.75 卵巣:6.07 精巣:5.74 心臓:9.43 骨格筋:7.87 食道:- 胃:7.29 腸:7.74 結腸:- 肝臓:10.78 肺:6.19 膀胱:7.67 腎臓:9.73 下垂体:5.36 甲状腺:- 副腎:8.04 膵臓:6.23 乳腺:6.56 唾液腺:6.29
CAGE 子宮:0.44 胎盤:0.11 前立腺:0.93 卵巣:1.63 精巣:0 心臓:- 骨格筋:- 食道:- 胃:1.35 腸:3.24 結腸:2.71     肝臓:5.19    肺:1.17 膀胱:2.19 腎臓:- 下垂体:0.70 甲状腺:- 副腎:1.45 膵臓:2.19 乳腺:0.42 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.81 食道:- 胃:- 腸:- 結腸:-     肝臓:10.30        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_001113418
Gene ID 19013
Unigene ID Mm.212789
Probe set ID 1449051_at  [Mouse430_2]
Ensembl ID ENSMUSG00000022383

オーソログ対応遺伝子

ヒト[4]  NM_001001928, NM_005036
ラット [0]  

染色体

15E2  [85,565,413  -  85,633,249]

遺伝子ファミリー (Interpro ID)

IPR003074  Peroxisome proliferator-activated receptor
IPR003076  Peroxisome proliferator-activated receptor, alpha
IPR001723  Steroid hormone receptor
IPR013088  Zinc finger, NHR/GATA-type
IPR001628  Zinc finger, nuclear hormone receptor-type

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0035095  behavioral response to nicotine
GO:0070166  enamel mineralization
GO:0008544  epidermis development
GO:0006631  fatty acid metabolic process
GO:0006006  glucose metabolic process
GO:0030522  intracellular receptor-mediated signaling pathway
GO:0006629  lipid metabolic process
GO:0042157  lipoprotein metabolic process
GO:0032099  negative regulation of appetite
GO:0045776  negative regulation of blood pressure
GO:0010887  negative regulation of cholesterol storage
GO:0010745  negative regulation of macrophage derived foam cell differentiation
GO:0032091  negative regulation of protein binding
GO:0010871  negative regulation of receptor biosynthetic process
GO:0010891  negative regulation of sequestering of triglyceride
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0046321  positive regulation of fatty acid oxidation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0019217  regulation of fatty acid metabolic process
GO:0010468  regulation of gene expression
GO:0006355  regulation of transcription, DNA-dependent
GO:0001666  response to hypoxia
GO:0032868  response to insulin stimulus
GO:0043401  steroid hormone mediated signaling pathway
GO:0006351  transcription, DNA-dependent
GO:0042060  wound healing

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0008144  drug binding
GO:0004879  ligand-dependent nuclear receptor activity
GO:0008289  lipid binding
GO:0046872  metal ion binding
GO:0051525  NFAT protein binding
GO:0019902  phosphatase binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0019904  protein domain specific binding
GO:0046982  protein heterodimerization activity
GO:0004872  receptor activity
GO:0043565  sequence-specific DNA binding
GO:0003707  steroid hormone receptor activity
GO:0003700  transcription factor activity
GO:0031624  ubiquitin conjugating enzyme binding
GO:0008270  zinc ion binding