Dicer1, Dcr-1 homolog (Drosophila)

詳細情報を見る

同義遺伝子名

mKIAA0928, 1110006F08Rik, Double-strand-specific ribonuclease mDCR-1, Mdcr, Endoribonuclease Dicer, D12Ertd7e, Dicer, Dicer1, Dicer1, Dcr-1 homolog (Drosophila)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:109.40 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:32.10 目:152 動脈:- 静脈:- リンパ節:- 末梢血:28.80 脾臓:13.20 胸腺:69.20 骨髄:- 脂肪:- 骨:37.60 皮膚:55.40
GeneChip 大脳:7.64 小脳:7.99 脳幹:- 脳梁:- 松果体:- 末梢神経:7.49 脊柱:7.34 網膜:8.49 目:7.67 動脈:- 静脈:7.70 リンパ節:7.86 末梢血:- 脾臓:7.93 胸腺:- 骨髄:7.61 脂肪:7.57 骨:7.40 皮膚:7.83
CAGE 大脳:2.86 小脳:- 脳幹:2.51 脳梁:- 松果体:- 末梢神経:- 脊柱:2.61 網膜:- 目:- 動脈:2.72 静脈:- リンパ節:3.15 末梢血:- 脾臓:2.65 胸腺:3.02 骨髄:- 脂肪:- 骨:2.59 皮膚:3.14
RNA-seq 大脳:2.39 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:55.20 前立腺:30.90 卵巣:287.30 精巣:59.10 心臓:- 骨格筋:35.50 食道:- 胃:- 腸:- 結腸:-     肝臓:9.10        肺:90.40    膀胱:132.40 腎臓:8.10 下垂体:38.80 甲状腺:112.50 副腎:424.40 膵臓:56.30 乳腺:45.70 唾液腺:-
GeneChip 子宮:7.61 胎盤:6.59 前立腺:7.74 卵巣:7.72 精巣:5.56 心臓:7.32 骨格筋:8.18 食道:- 胃:7.21 腸:7.47 結腸:- 肝臓:7.75 肺:7.94 膀胱:7.81 腎臓:7.25 下垂体:8.41 甲状腺:- 副腎:8.30 膵臓:7.26 乳腺:7.79 唾液腺:7.91
CAGE 子宮:2.85 胎盤:2.75 前立腺:2.59 卵巣:2.81 精巣:2.46 心臓:- 骨格筋:- 食道:- 胃:1.57 腸:2.78 結腸:2.68     肝臓:2.87    肺:2.90 膀胱:3.08 腎臓:- 下垂体:3.14 甲状腺:- 副腎:2.75 膵臓:3.27 乳腺:2.75 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.28 食道:- 胃:- 腸:- 結腸:-     肝臓:2.73        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_148948
Gene ID 192119
Unigene ID Mm.21135
Probe set ID 1460571_at  [Mouse430_2]
Ensembl ID ENSMUSG00000041415

オーソログ対応遺伝子

ヒト[6]  NM_001195573, NM_030621, NM_177438
ラット[6]  NM_001195573, NM_030621, NM_177438

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

8889548
10349636
10512203
10725249
10922068
11042159
11076861
11217851
11889553
12466851
12477932
12520002
12526743
14528307
14610273
14621295
14681479
15033168
15081373
15576842
15613470
15713842
15840001
15867090
16009718
16036130
16040801
16092937
16099834
16141072
16141073
16182285
16319892
16397794
16452165
16462742
16575173
16682203
16938833
17060477
17113034
17135486
17369397
17369401
17401365
17452327
17606634
17613256
17761882
17804764
17936265
17989215
18157120
18184563
18238902
18256189
18268334
18320056
18329371
18385371
18398510
18404146
18404147
18410515
18434510
18463241
18535243
18554416
18591425
18604195
18633141
18687735
18703631
18725525
18725526
18725527
18776119
18776121
18779589
18799693
18809798
18997113
19059913
19071104
19114655
19118902
19127519
19129368
19144718
19148298
19164542
19169742
19197916
19272382
19389351
19416898
19422693
19509335
19625646
19646895
19681134
19718708
19799966
19806666
19876815
19898466
19903759
20018673
20019750
20035504
20039311
20056748
20079730
20102707
20103535
20116252
20144605
20167638
20211135
20223197
20223198
20237275
20299448
20305640
20353723
20360310
20378849
20386732
20452309
20457670
20463238
20504959
20517984
20519547
20530258
20540774
20550935
20554876
20587524
20596657
20603000
20616003
20616011
20643829
20659473
20660113
20699384
20702715
20708584
20713509
20730047
20805417
20805985
20807761
20827505
20852262
20852728
20884876
20944551
20945399
20956382
20962848
20975942
20976144
21048142
21048966
21093320
21098294
21098571
21138975
21149603
21225654
21256124
21256960
21267068
21273303
21278735
21285947
21297615
21307095
21338882
21360794
21371421
21447562
21526127
21533178
21542136
21544061
21573140
21632951
21677750
21712401
21730146
21731673
21788498
21796153
21807765
21826226
21841785
21911408
21945074
21949761
21969379
21991391
21998645
22053081
22106413
22113163
22117047
22131398
22132122
22179202
22198669
22216196
22225602
22242190
22270084
22308344
22313051
22326846
22331912
22353998
22358842
22379031
22379033
22434867
22447776
22474261
22475483
22492706
22503104
22504928
22508726
22521588
22541070
22558254
22564735
22580128
22615744
22629237
22661094
22665486
22665768
22684508
22698408
22701646
22706270
22737231
22753148
22778034
22796409
22798293
22801545
22819339
22836445
22836757
22844247
22858543
22864477
22869729
22869792
22874921
22898830
22916300
22918229
22925886
22952873
22958919
22969435
22972926
22982054
22991506
22993445
23056286
23063653
23132766
23141545
23152916
23284137
23311378
23321074
23349485
23382448
23427252
23498953
23518926
23569256
23622242
23716939
23754433
23840532
23895693
23918385
23961995
23974039
24012747
24023722
24163352
24209619
24287487
24381269
24497637
24500693
24690185

遺伝子オントロジー  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0048754  branching morphogenesis of a tube
GO:0055013  cardiac muscle cell development
GO:0008283  cell proliferation
GO:0021987  cerebral cortex development
GO:0051607  defense response to virus
GO:0035116  embryonic hindlimb morphogenesis
GO:0030326  embryonic limb morphogenesis
GO:0048730  epidermis morphogenesis
GO:0031047  gene silencing by RNA
GO:0048565  gut development
GO:0071335  hair follicle cell proliferation
GO:0001942  hair follicle development
GO:0031069  hair follicle morphogenesis
GO:0060119  inner ear receptor cell development
GO:0060576  intestinal epithelial cell development
GO:0030324  lung development
GO:0008152  metabolic process
GO:0035264  multicellular organism growth
GO:0032290  myelin formation in the peripheral nervous system
GO:0060253  negative regulation of glial cell proliferation
GO:0010626  negative regulation of Schwann cell proliferation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0021675  nerve development
GO:0048812  neuron projection morphogenesis
GO:0021889  olfactory bulb interneuron differentiation
GO:0010628  positive regulation of gene expression
GO:0031643  positive regulation of myelination
GO:0014040  positive regulation of Schwann cell differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0009791  post-embryonic development
GO:0031054  pre-microRNA processing
GO:0035196  production of miRNAs involved in gene silencing by miRNA
GO:0030422  production of siRNA involved in RNA interference
GO:0051726  regulation of cell cycle
GO:0045595  regulation of cell differentiation
GO:0070173  regulation of enamel mineralization
GO:0010468  regulation of gene expression
GO:0031641  regulation of myelination
GO:0050767  regulation of neurogenesis
GO:0045664  regulation of neuron differentiation
GO:0008593  regulation of Notch signaling pathway
GO:0042487  regulation of odontogenesis of dentine-containing tooth
GO:0048713  regulation of oligodendrocyte differentiation
GO:0001932  regulation of protein amino acid phosphorylation
GO:0045069  regulation of viral genome replication
GO:0006396  RNA processing
GO:0016075  rRNA catabolic process
GO:0021522  spinal cord motor neuron differentiation
GO:0051225  spindle assembly
GO:0048536  spleen development
GO:0019827  stem cell maintenance
GO:0030423  targeting of mRNA for destruction involved in RNA interference
GO:0010070  zygote asymmetric cell division

Cellular Component

GO:0030424  axon
GO:0005737  cytoplasm
GO:0030425  dendrite
GO:0005793  ER-Golgi intermediate compartment
GO:0030426  growth cone
GO:0016442  RNA-induced silencing complex

Molecular Function

GO:0005524  ATP binding
GO:0008026  ATP-dependent helicase activity
GO:0003725  double-stranded RNA binding
GO:0004519  endonuclease activity
GO:0016891  endoribonuclease activity, producing 5'-phosphomonoesters
GO:0004386  helicase activity
GO:0016787  hydrolase activity
GO:0046872  metal ion binding
GO:0035198  miRNA binding
GO:0004518  nuclease activity
GO:0003676  nucleic acid binding
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0004525  ribonuclease III activity
GO:0003723  RNA binding