PTK2 protein tyrosine kinase 2 beta

同義遺伝子名

calcium-dependent tyrosine kinase, Cell adhesion kinase beta, FADK 2, Ptk2b, PYK2, FAK2, E430023O05Rik, Raftk, Fak2, related adhesion focal tyrosine kinase, proline-rich tyrosine kinase 2, Protein tyrosine kinase 2 beta, CAKB, Proline-rich tyrosine kinase 2, CAK[B], A6, RAFTK, Pyk2, CAK beta, CAKbeta, Related adhesion focal tyrosine kinase, PTK, CADTK, PTK2 protein tyrosine kinase 2 beta, Focal adhesion kinase 2, Calcium-dependent tyrosine kinase, cellular adhesion kinase beta

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:3.50

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:12.80

脂肪:-

骨:50.10

皮膚:7.90

GeneChip

大脳:10.60

小脳:5.65

脳幹:-

脳梁:-

松果体:-

末梢神経:7.29

脊柱:5.80

網膜:5.70

目:6.83

動脈:-

静脈:6.57

リンパ節:10.29

末梢血:-

脾臓:10.58

胸腺:-

骨髄:9.05

脂肪:7.69

骨:8.82

皮膚:7.26

CAGE

大脳:3.79

小脳:-

脳幹:3.11

脳梁:-

松果体:-

末梢神経:-

脊柱:1.94

網膜:-

目:-

動脈:3.80

静脈:-

リンパ節:4.81

末梢血:-

脾臓:4.16

胸腺:4.71

骨髄:-

脂肪:-

骨:4.25

皮膚:3.56

RNA-seq

大脳:61.35

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:13.80

前立腺:-

卵巣:-

精巣:44.30

心臓:-

骨格筋:-

食道:-

胃:-

腸:37

結腸:-

肝臓:-

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

GeneChip

子宮:7.89

胎盤:6.55

前立腺:6.95

卵巣:8.04

精巣:7.27

心臓:6.66

骨格筋:5.96

食道:-

胃:7.67

腸:8.42

結腸:-

肝臓:8.02

肺:7.36

膀胱:8.44

腎臓:8.63

下垂体:8.15

甲状腺:-

副腎:6.76

膵臓:7.69

乳腺:7.28

唾液腺:7.22

CAGE

子宮:3.76

胎盤:2.26

前立腺:3.51

卵巣:3.59

精巣:1.97

心臓:-

骨格筋:-

食道:-

胃:3.59

腸:3.50

結腸:4.01

肝臓:3.76

肺:3.92

膀胱:4.33

腎臓:-

下垂体:4.16

甲状腺:-

副腎:2.69

膵臓:2.90

乳腺:2.81

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.32

食道:-

胃:-

腸:-

結腸:-

肝臓:8.99

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_001162366
Gene ID	19229
Unigene ID	Mm.216135
Probe set ID	1434653_at [Mouse430_2]
Ensembl ID	ENSMUSG00000059456

オーソログ対応遺伝子

ヒト[8]	NM_004103, NM_173174, NM_173175, NM_173176
ラット [0]

染色体

14D1 [66,772,094 - 66,899,889]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR019749	Band 4.1 domain
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0007015	actin filament organization
GO:0042976	activation of Janus kinase activity
GO:0032863	activation of Rac GTPase activity
GO:0001525	angiogenesis
GO:0043534	blood vessel endothelial cell migration
GO:0045453	bone resorption
GO:0007155	cell adhesion
GO:0007166	cell surface receptor linked signal transduction
GO:0071300	cellular response to retinoic acid
GO:0070098	chemokine-mediated signaling pathway
GO:0007204	elevation of cytosolic calcium ion concentration
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0048041	focal adhesion formation
GO:0007229	integrin-mediated signaling pathway
GO:0000165	MAPKKK cascade
GO:0002315	marginal zone B cell differentiation
GO:0043066	negative regulation of apoptosis
GO:0030502	negative regulation of bone mineralization
GO:0008285	negative regulation of cell proliferation
GO:0010656	negative regulation of muscle cell apoptosis
GO:0045638	negative regulation of myeloid cell differentiation
GO:0030279	negative regulation of ossification
GO:0043267	negative regulation of potassium ion transport
GO:0031175	neuron projection development
GO:0001556	oocyte maturation
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0016310	phosphorylation
GO:0030838	positive regulation of actin filament polymerization
GO:0045766	positive regulation of angiogenesis
GO:0030307	positive regulation of cell growth
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0001954	positive regulation of cell-matrix adhesion
GO:0010595	positive regulation of endothelial cell migration
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0046330	positive regulation of JNK cascade
GO:0043507	positive regulation of JUN kinase activity
GO:0010976	positive regulation of neuron projection development
GO:0051000	positive regulation of nitric-oxide synthase activity
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0043552	positive regulation of phosphoinositide 3-kinase activity
GO:0045860	positive regulation of protein kinase activity
GO:0045727	positive regulation of translation
GO:0006468	protein amino acid phosphorylation
GO:0050848	regulation of calcium-mediated signaling
GO:0030155	regulation of cell adhesion
GO:0008360	regulation of cell shape
GO:0030826	regulation of cGMP biosynthetic process
GO:0010752	regulation of cGMP-mediated signaling
GO:0032960	regulation of inositol trisphosphate biosynthetic process
GO:0010758	regulation of macrophage chemotaxis
GO:0045428	regulation of nitric oxide biosynthetic process
GO:0051279	regulation of release of sequestered calcium ion into cytosol
GO:0042542	response to hydrogen peroxide
GO:0007172	signal complex assembly
GO:0002040	sprouting angiogenesis
GO:0043149	stress fiber formation
GO:0033209	tumor necrosis factor-mediated signaling pathway
GO:0048010	vascular endothelial growth factor receptor signaling pathway

Cellular Component

GO:0030424	axon
GO:0005938	cell cortex
GO:0030054	cell junction
GO:0042995	cell projection
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005925	focal adhesion
GO:0030426	growth cone
GO:0030027	lamellipodium
GO:0016020	membrane
GO:0045121	membrane raft
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm
GO:0005886	plasma membrane
GO:0014069	postsynaptic density

Molecular Function

GO:0043423	3-phosphoinositide-dependent protein kinase binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0004715	non-membrane spanning protein tyrosine kinase activity
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0032403	protein complex binding
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0004871	signal transducer activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

PTK2 protein tyrosine kinase 2 beta

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function