protein tyrosine phosphatase, non-receptor type 11

詳細情報を見る

同義遺伝子名

SH-PTP2, Syp, 2700084A17Rik, AW536184, Ptpn11, SH-PTP3, protein tyrosine phosphatase, non-receptor type 11, Protein-tyrosine phosphatase SYP, SHP-2, Shp2, SAP-2, PTP2C, Tyrosine-protein phosphatase non-receptor type 11, PTP1D

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:128.50 小脳:18.40 脳幹:- 脳梁:- 松果体:- 末梢神経:38.20 脊柱:- 網膜:192.90 目:129.20 動脈:- 静脈:- リンパ節:- 末梢血:14.40 脾臓:- 胸腺:88.90 骨髄:- 脂肪:212.70 骨:150.30 皮膚:39.60
GeneChip 大脳:5.42 小脳:5.53 脳幹:- 脳梁:- 松果体:- 末梢神経:5.57 脊柱:5.74 網膜:6.58 目:6.42 動脈:- 静脈:5.45 リンパ節:5.25 末梢血:- 脾臓:5.27 胸腺:- 骨髄:5.61 脂肪:5.92 骨:5.11 皮膚:5.42
CAGE 大脳:3.87 小脳:- 脳幹:4.05 脳梁:- 松果体:- 末梢神経:- 脊柱:4.26 網膜:- 目:- 動脈:4.06 静脈:- リンパ節:3.08 末梢血:- 脾臓:3.54 胸腺:3.17 骨髄:- 脂肪:- 骨:4.02 皮膚:4.20
RNA-seq 大脳:10.09 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:248.50 前立腺:- 卵巣:68.90 精巣:36.90 心臓:- 骨格筋:71 食道:- 胃:- 腸:- 結腸:17.60     肝臓:18.10        肺:100.40    膀胱:66.20 腎臓:48.40 下垂体:- 甲状腺:- 副腎:- 膵臓:37.50 乳腺:81.60 唾液腺:54
GeneChip 子宮:5.10 胎盤:6.54 前立腺:5.03 卵巣:5.25 精巣:5.13 心臓:6.49 骨格筋:5.62 食道:- 胃:5.15 腸:5.17 結腸:- 肝臓:5.19 肺:5.14 膀胱:5.62 腎臓:5.41 下垂体:5.30 甲状腺:- 副腎:5.77 膵臓:5.72 乳腺:5.37 唾液腺:5.46
CAGE 子宮:3.42 胎盤:4.16 前立腺:4.25 卵巣:3.61 精巣:2.25 心臓:- 骨格筋:- 食道:- 胃:3.05 腸:3.26 結腸:3.26     肝臓:3.64    肺:3.73 膀胱:4.20 腎臓:- 下垂体:3.97 甲状腺:- 副腎:3.94 膵臓:3.64 乳腺:3.33 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:5.93 食道:- 胃:- 腸:- 結腸:-     肝臓:4.24        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_001109992
Gene ID 19247
Unigene ID Mm.8681
Probe set ID 1427699_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000043733

オーソログ対応遺伝子

ヒト[10]  NM_002834
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

7521735
7522233
7523381
7681217
8096088
8183548
8479755
8505282
8530013
8620532
8702915
8810330
8875997
8889548
8955893
8959326
9062191
9070220
9110989
9171349
9271425
9299490
9393882
9422771
9670943
9742124
9867848
10097116
10349636
10411909
10512203
10521483
10700187
10742110
10862698
10896938
10922068
11023980
11042159
11076861
11159516
11217851
11432792
11533026
11684012
11739737
11832424
11895767
11970986
11997521
12024020
12181353
12219085
12270932
12466851
12477932
12482708
12520002
12522270
12582165
12594211
12611902
12615921
12791646
12796776
12808090
12893283
12904583
12913007
12923167
12937170
12955078
12971893
14514016
14522994
14534538
14610044
14610273
14967142
14967925
15169898
15215307
15273746
15477348
15489334
15520383
15548697
15563458
15568026
15569927
15574420
15611085
15650750
15677447
15699129
15710330
15723811
15737732
15741177
15761018
15840001
15870281
15950607
16055440
16141072
16141073
16179375
16239343
16260787
16272304
16284184
16371368
16442778
16461457
16516835
16602821
16702225
16731527
16738330
16837792
16873377
16885344
16939816
16959766
16963136
17015617
17056523
17082620
17095659
17157040
17213291
17229738
17239631
17330819
17369354
17442246
17487421
17605785
17646384
17804806
17881575
17961593
17962719
17971444
18077586
18223690
18246201
18316486
18368066
18378677
18403587
18450421
18640765
18799693
18827006
19001090
19008228
19017799
19036852
19179468
19251646
19261604
19275884
19287004
19290061
19380737
19393645
19433062
19509418
19528235
19541608
19542364
19587381
19635473
19637226
19679834
19698715
19727691
19786542
19805360
19887591
20160350
20215346
20237281
20400923
20417562
20421975
20435932
20472558
20526344
20648636
20651068
20682772
20697350
20723025
20734316
20841350
20846526
20884876
21056449
21068439
21297004
21339643
21353259
21364532
21393858
21398220
21450902
21531714
21575863
21576358
21636860
21677750
21725048
21803945
21804557
21884940
21903867
21930766
22015719
22058153
22362894
22371576
22389718
22431513
22522491
22566685
22619361
22641383
22759635
22806893
22890240
22891281
22942432
23027125
23057634
23103841
23129808
23236157
23269672
23321074
23349485
23374343
23382182
23452850
23509158
23530062
23675459
23720040
23863940
23873233
23884424
24030516
24035415
24077964
24088816
24123360
24216759
24431450
24493648
24550486
24553178
24599474
24706815
24733849

遺伝子オントロジー  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0007409  axonogenesis
GO:0007420  brain development
GO:0016311  dephosphorylation
GO:0000077  DNA damage checkpoint
GO:0048013  ephrin receptor signaling pathway
GO:0060325  face morphogenesis
GO:0048806  genitalia development
GO:0042593  glucose homeostasis
GO:0007507  heart development
GO:0042445  hormone metabolic process
GO:0009755  hormone-mediated signaling pathway
GO:0048839  inner ear development
GO:0006629  lipid metabolic process
GO:0051463  negative regulation of cortisol secretion
GO:0060125  negative regulation of growth hormone secretion
GO:0046888  negative regulation of hormone secretion
GO:0046676  negative regulation of insulin secretion
GO:0048011  nerve growth factor receptor signaling pathway
GO:0035265  organ growth
GO:0046887  positive regulation of hormone secretion
GO:0009967  positive regulation of signal transduction
GO:0006470  protein amino acid dephosphorylation
GO:0033628  regulation of cell adhesion mediated by integrin
GO:0040014  regulation of multicellular organism growth
GO:0046825  regulation of protein export from nucleus
GO:0048609  reproductive process in a multicellular organism
GO:0006641  triglyceride metabolic process

Cellular Component

GO:0030054  cell junction
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0016020  membrane
GO:0005739  mitochondrion
GO:0005634  nucleus
GO:0043234  protein complex
GO:0001725  stress fiber

Molecular Function

GO:0016787  hydrolase activity
GO:0005158  insulin receptor binding
GO:0043560  insulin receptor substrate binding
GO:0004726  non-membrane spanning protein tyrosine phosphatase activity
GO:0051428  peptide hormone receptor binding
GO:0016791  phosphatase activity
GO:0043274  phospholipase binding
GO:0004721  phosphoprotein phosphatase activity
GO:0005515  protein binding
GO:0019904  protein domain specific binding
GO:0004725  protein tyrosine phosphatase activity
GO:0030971  receptor tyrosine kinase binding
GO:0005070  SH3/SH2 adaptor activity