protein tyrosine phosphatase, receptor type, C

詳細情報を見る

同義遺伝子名

CD45 antigen, Cd45, L-CA, Ptprc, Ly-5, CD45, Leukocyte common antigen precursor, CD45R, Lymphocyte common antigen Ly-5, Lyt-4, loc, protein tyrosine phosphatase, receptor type, C, B220, T200

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:1.70 小脳:36.80 脳幹:- 脳梁:- 松果体:- 末梢神経:57.30 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:518.50 末梢血:2717.20 脾臓:1119.10 胸腺:316.20 骨髄:102.60 脂肪:- 骨:37.60 皮膚:23.80
GeneChip 大脳:5.65 小脳:4.37 脳幹:- 脳梁:- 松果体:- 末梢神経:6.16 脊柱:5.59 網膜:6.92 目:6.48 動脈:- 静脈:7.59 リンパ節:13.39 末梢血:- 脾臓:13.32 胸腺:- 骨髄:12.44 脂肪:8.45 骨:12.58 皮膚:8.87
CAGE 大脳:0.91 小脳:- 脳幹:0.85 脳梁:- 松果体:- 末梢神経:- 脊柱:2.04 網膜:- 目:- 動脈:4.11 静脈:- リンパ節:7.65 末梢血:- 脾臓:5.94 胸腺:6.67 骨髄:- 脂肪:- 骨:5.15 皮膚:3.15
RNA-seq 大脳:0.80 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:17.60     肝臓:-        肺:60.30    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:848.90 膵臓:18.80 乳腺:39.20 唾液腺:-
GeneChip 子宮:9.83 胎盤:6.59 前立腺:6.94 卵巣:8.14 精巣:4.10 心臓:7.47 骨格筋:8.13 食道:- 胃:7.21 腸:8.71 結腸:- 肝臓:7.74 肺:10.32 膀胱:7.99 腎臓:7.01 下垂体:5.97 甲状腺:- 副腎:8.38 膵臓:7.49 乳腺:10.22 唾液腺:8.82
CAGE 子宮:3.34 胎盤:2.09 前立腺:2.00 卵巣:2.93 精巣:0.75 心臓:- 骨格筋:- 食道:- 胃:2.26 腸:2.89 結腸:3.86     肝臓:2.85    肺:5.24 膀胱:2.90 腎臓:- 下垂体:2.25 甲状腺:- 副腎:3.70 膵臓:2.66 乳腺:3.99 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.45 食道:- 胃:- 腸:- 結腸:-     肝臓:2.31        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_001111316
Gene ID 19264
Unigene ID Mm.391573
Probe set ID 1422124_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000026395

オーソログ対応遺伝子

ヒト[7]  NM_002838, NM_080921, NM_080923
ラット[16]  NM_001109887, NM_001109888, NM_001109889, NM_001109890, NM_138507

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

61878
62795
1290451
1350294
1431091
1454056
1683707
1686571
1822988
1834169
1932742
2522930
2567701
2574151
2574991
2744450
2845400
2885153
2886425
2894402
2944116
2948186
2955416
2971731
2978372
3037546
3211131
3384439
3416634
3417340
3489673
3570377
3817907
3864163
4042679
6233370
6602762
6607883
6610701
6983999
7287081
7477352
7477353
7499277
7509278
7511063
7558020
7558021
7562081
7589135
7630421
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7743522
7751624
7806287
7807014
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7889403
8041705
8043862
8046327
8101401
8175795
8288230
8334701
8452817
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8632004
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8747928
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8788039
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9148925
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9376320
9581568
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10067894
10330160
10330270
10349636
10358768
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10403645
10429672
10458749
10508267
10556550
10575213
10631184
10648121
10749569
10770800
10829061
10848813
10906147
10926756
10943840
10943842
10970857
11042159
11076861
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11163182
11201744
11217851
11260323
11342624
11466198
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11544199
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11716526
11884039
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12004082
12022705
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12055218
12068292
12091326
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12414501
12466851
12477932
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12900455
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12922168
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15070695
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15138500
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15499555
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15723811
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15823427
15845452
15845899
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15867094
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16020514
16025105
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16319116
16332974
16356861
16361310
16378097
16455951
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16493007
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16505159
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16602821
16616894
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16627620
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16771860
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16856204
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16912273
16925795
17159898
17177603
17213291
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17277142
17287827
17339442
17383624
17404256
17420226
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17517650
17521585
17655922
17683113
17719247
17762938
17804806
17846664
17855428
17897956
17923504
17923507
17941951
17954566
17991461
18059271
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18086862
18086865
18178216
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18249142
18337659
18374325
18403646
18413859
18426908
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18602924
18627106
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19841086
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20043899
20130220
20208005
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20624943
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20709950
20802149
20805985
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20890286
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21098236
21108466
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21181199
21245479
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21300983
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21469133
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21502514
21515254
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21606356
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21633705
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21816924
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23883515
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24029230
24123684
24141946
24143212
24255917
24478402
24639353
24681564
24745333

遺伝子オントロジー  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0030183  B cell differentiation
GO:0042100  B cell proliferation
GO:0050853  B cell receptor signaling pathway
GO:0048539  bone marrow development
GO:0051607  defense response to virus
GO:0016311  dephosphorylation
GO:0002244  hemopoietic progenitor cell differentiation
GO:0034113  heterotypic cell-cell adhesion
GO:0002378  immunoglobulin biosynthetic process
GO:0007159  leukocyte adhesion
GO:0008152  metabolic process
GO:0006933  negative regulation of cell adhesion involved in substrate-bound cell migration
GO:0001960  negative regulation of cytokine-mediated signaling pathway
GO:0050732  negative regulation of peptidyl-tyrosine phosphorylation
GO:0031953  negative regulation of protein amino acid autophosphorylation
GO:0006469  negative regulation of protein kinase activity
GO:0001915  negative regulation of T cell mediated cytotoxicity
GO:0045060  negative thymic T cell selection
GO:0046641  positive regulation of alpha-beta T cell proliferation
GO:0050857  positive regulation of antigen receptor-mediated signaling pathway
GO:0030890  positive regulation of B cell proliferation
GO:0045588  positive regulation of gamma-delta T cell differentiation
GO:0002925  positive regulation of humoral immune response mediated by circulating immunoglobulin
GO:0048304  positive regulation of isotype switching to IgG isotypes
GO:0043410  positive regulation of MAPKKK cascade
GO:0045582  positive regulation of T cell differentiation
GO:0001916  positive regulation of T cell mediated cytotoxicity
GO:0002711  positive regulation of T cell mediated immunity
GO:0042102  positive regulation of T cell proliferation
GO:0045059  positive thymic T cell selection
GO:0006470  protein amino acid dephosphorylation
GO:0045577  regulation of B cell differentiation
GO:0050855  regulation of B cell receptor signaling pathway
GO:0051726  regulation of cell cycle
GO:0002923  regulation of humoral immune response mediated by circulating immunoglobulin
GO:0033261  regulation of S phase
GO:0051209  release of sequestered calcium ion into cytosol
GO:0010332  response to gamma radiation
GO:0048864  stem cell development
GO:0030217  T cell differentiation
GO:0042098  T cell proliferation
GO:0050852  T cell receptor signaling pathway

Cellular Component

GO:0009986  cell surface
GO:0009897  external side of plasma membrane
GO:0005925  focal adhesion
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0043395  heparan sulfate proteoglycan binding
GO:0008201  heparin binding
GO:0016787  hydrolase activity
GO:0016791  phosphatase activity
GO:0004721  phosphoprotein phosphatase activity
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0004725  protein tyrosine phosphatase activity