receptor (TNFRSF)-interacting serine-threonine kinase 2

詳細情報を見る

同義遺伝子名

Ripk2, RICK, D4Bwg0615e, CARDIAK, CARD3, CCK

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:5.20

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:32.10

目:7.60

動脈:-

静脈:-

リンパ節:10.80

末梢血:43.10

脾臓:158

胸腺:-

骨髄:-

脂肪:-

骨:87.70

皮膚:15.80

GeneChip

大脳:6.12

小脳:6.05

脳幹:-

脳梁:-

松果体:-

末梢神経:6.12

脊柱:6.21

網膜:6.01

目:7.01

動脈:-

静脈:6.40

リンパ節:6.50

末梢血:-

脾臓:6.69

胸腺:-

骨髄:6.39

脂肪:6.25

骨:6.12

皮膚:6.67

CAGE

大脳:1.81

小脳:-

脳幹:1.67

脳梁:-

松果体:-

末梢神経:-

脊柱:1.70

網膜:-

目:-

動脈:3.40

静脈:-

リンパ節:3.82

末梢血:-

脾臓:2.97

胸腺:2.22

骨髄:-

脂肪:-

骨:2.77

皮膚:3.53

RNA-seq

大脳:1.33

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:13.80

前立腺:-

卵巣:23

精巣:-

心臓:18.60

骨格筋:71

食道:-

胃:65.50

腸:-

結腸:17.60

肝臓:-

肺:10

膀胱:-

腎臓:8.10

下垂体:-

甲状腺:-

副腎:-

膵臓:37.50

乳腺:32.60

唾液腺:-

GeneChip

子宮:6.33

胎盤:6.27

前立腺:6.30

卵巣:6.31

精巣:6.04

心臓:6.38

骨格筋:6.14

食道:-

胃:6.15

腸:6.52

結腸:-

肝臓:6.62

肺:6.37

膀胱:6.37

腎臓:6.20

下垂体:6.36

甲状腺:-

副腎:6.28

膵臓:6.01

乳腺:6.22

唾液腺:6.48

CAGE

子宮:3.21

胎盤:2.49

前立腺:3.10

卵巣:3.18

精巣:1.80

心臓:-

骨格筋:-

食道:-

胃:2.60

腸:2.13

結腸:2.30

肝臓:3.13

肺:3.09

膀胱:2.87

腎臓:-

下垂体:2.48

甲状腺:-

副腎:2.83

膵臓:2.45

乳腺:1.78

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:2.79

食道:-

胃:-

腸:-

結腸:-

肝臓:2.26

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_138952
Gene ID	192656
Unigene ID	Mm.112765
Probe set ID	1421236_at [Mouse430_2]
Ensembl ID	ENSMUSG00000041135

オーソログ対応遺伝子

ヒト[2]	NM_003821
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR001315	Caspase Recruitment
IPR011029	DEATH-like
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0002250	adaptive immune response
GO:0006915	apoptosis
GO:0071222	cellular response to lipopolysaccharide
GO:0071223	cellular response to lipoteichoic acid
GO:0071224	cellular response to peptidoglycan
GO:0050830	defense response to Gram-positive bacterium
GO:0007249	I-kappaB kinase/NF-kappaB cascade
GO:0045087	innate immune response
GO:0031663	lipopolysaccharide-mediated signaling pathway
GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0016310	phosphorylation
GO:0046641	positive regulation of alpha-beta T cell proliferation
GO:0043065	positive regulation of apoptosis
GO:0032722	positive regulation of chemokine production
GO:0001961	positive regulation of cytokine-mediated signaling pathway
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0033091	positive regulation of immature T cell proliferation
GO:0032729	positive regulation of interferon-gamma production
GO:0032743	positive regulation of interleukin-2 production
GO:0032755	positive regulation of interleukin-6 production
GO:0046330	positive regulation of JNK cascade
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0031398	positive regulation of protein ubiquitination
GO:0032874	positive regulation of stress-activated MAPK cascade
GO:0045627	positive regulation of T-helper 1 cell differentiation
GO:0002827	positive regulation of T-helper 1 type immune response
GO:0032760	positive regulation of tumor necrosis factor production
GO:0006468	protein amino acid phosphorylation
GO:0042981	regulation of apoptosis
GO:0043281	regulation of caspase activity
GO:0043330	response to exogenous dsRNA
GO:0070555	response to interleukin-1
GO:0070671	response to interleukin-12
GO:0070673	response to interleukin-18
GO:0042098	T cell proliferation
GO:0050852	T cell receptor signaling pathway
GO:0034134	toll-like receptor 2 signaling pathway
GO:0034142	toll-like receptor 4 signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0005622	intracellular

Molecular Function

GO:0005524	ATP binding
GO:0050700	CARD domain binding
GO:0016301	kinase activity
GO:0030274	LIM domain binding
GO:0004715	non-membrane spanning protein tyrosine kinase activity
GO:0000166	nucleotide binding
GO:0042803	protein homodimerization activity
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

receptor (TNFRSF)-interacting serine-threonine kinase 2

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function