ret proto-oncogene

 詳細情報を見る

同義遺伝子名

RET51, ret proto-oncogene, RET9, C-ret, Ret, PTC

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:26 小脳:92.10 脳幹:- 脳梁:- 松果体:- 末梢神経:133.80 脊柱:94.60 網膜:96.40 目:7.60 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:12.50 皮膚:7.90
GeneChip 大脳:5.28 小脳:5.77 脳幹:- 脳梁:- 松果体:- 末梢神経:10.06 脊柱:7.94 網膜:4.92 目:5.16 動脈:- 静脈:5.46 リンパ節:5.03 末梢血:- 脾臓:5.06 胸腺:- 骨髄:5 脂肪:5.61 骨:5.43 皮膚:5.25
CAGE 大脳:1.86 小脳:- 脳幹:3.80 脳梁:- 松果体:- 末梢神経:- 脊柱:4.18 網膜:- 目:- 動脈:1.53 静脈:- リンパ節:0.71 末梢血:- 脾臓:0.29 胸腺:0.27 骨髄:- 脂肪:- 骨:0.63 皮膚:2.33
RNA-seq 大脳:3.77 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:43.60 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:71 食道:- 胃:- 腸:- 結腸:17.60     肝臓:-        肺:20.10    膀胱:66.20 腎臓:- 下垂体:- 甲状腺:224.90 副腎:- 膵臓:56.30 乳腺:13.10 唾液腺:-
GeneChip 子宮:6.28 胎盤:5.39 前立腺:5.53 卵巣:5.16 精巣:5.18 心臓:6.02 骨格筋:6.20 食道:- 胃:5.73 腸:5.52 結腸:- 肝臓:5.47 肺:5.31 膀胱:5.01 腎臓:4.97 下垂体:5.80 甲状腺:- 副腎:5 膵臓:5.74 乳腺:5.47 唾液腺:6.70
CAGE 子宮:2.71 胎盤:0.89 前立腺:2.93 卵巣:1.14 精巣:0.45 心臓:- 骨格筋:- 食道:- 胃:1.07 腸:2.38 結腸:1.63     肝臓:0    肺:0.91 膀胱:2.33 腎臓:- 下垂体:0.99 甲状腺:- 副腎:0.71 膵臓:1.61 乳腺:2.11 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.61 食道:- 胃:- 腸:- 結腸:-     肝臓:0        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_009050
Gene ID 19713
Unigene ID Mm.57199
Probe set ID 1421359_at  [Mouse430_2]
Ensembl ID ENSMUSG00000030110

オーソログ対応遺伝子

ヒト[5]  NM_020630, NM_020975
ラット[4]  NM_001110099, NM_012643

染色体

-

遺伝子ファミリー (Interpro ID)

IPR002126  Cadherin
IPR015919  Cadherin-like
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR020685  Tyrosine-protein kinase
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020933  Tyrosine-protein kinase, fibroblast growth factor receptor, conserved region
IPR016249  Tyrosine-protein kinase, Ret receptor
IPR015777  Tyrosine-protein kinase, Ret receptor-like
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

1374037
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0009653  anatomical structure morphogenesis
GO:0007155  cell adhesion
GO:0071300  cellular response to retinoic acid
GO:0001838  embryonic epithelial tube formation
GO:0048484  enteric nervous system development
GO:0007156  homophilic cell adhesion
GO:0060384  innervation
GO:0000165  MAPKKK cascade
GO:0033619  membrane protein proteolysis
GO:0007399  nervous system development
GO:0001755  neural crest cell migration
GO:0007158  neuron adhesion
GO:0030182  neuron differentiation
GO:0042551  neuron maturation
GO:0016310  phosphorylation
GO:0033630  positive regulation of cell adhesion mediated by integrin
GO:0030335  positive regulation of cell migration
GO:0045793  positive regulation of cell size
GO:0014042  positive regulation of neuron maturation
GO:0010976  positive regulation of neuron projection development
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0006468  protein amino acid phosphorylation
GO:0050770  regulation of axonogenesis
GO:0030155  regulation of cell adhesion
GO:0048265  response to pain
GO:0007165  signal transduction
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway
GO:0001657  ureteric bud development

Cellular Component

GO:0005768  endosome
GO:0010008  endosome membrane
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0045121  membrane raft
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0005509  calcium ion binding
GO:0016301  kinase activity
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0004713  protein tyrosine kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups
GO:0004714  transmembrane receptor protein tyrosine kinase activity