receptor (TNFRSF)-interacting serine-threonine kinase 1

同義遺伝子名

Receptor-interacting protein, Ripk1, Rinp, D330015H01Rik, Cell death protein RIP, Serine/threonine-protein kinase RIP, RIP

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:17.40

小脳:55.30

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:32.10

目:30.40

動脈:-

静脈:-

リンパ節:21.60

末梢血:71.90

脾臓:52.70

胸腺:59.30

骨髄:38.50

脂肪:212.70

骨:25

皮膚:39.60

GeneChip

大脳:5.53

小脳:5.76

脳幹:-

脳梁:-

松果体:-

末梢神経:5.95

脊柱:5.86

網膜:6.63

目:7.64

動脈:-

静脈:8.28

リンパ節:8.89

末梢血:-

脾臓:8.74

胸腺:-

骨髄:9.03

脂肪:7.94

骨:8.88

皮膚:7.89

CAGE

大脳:1.90

小脳:-

脳幹:1.90

脳梁:-

松果体:-

末梢神経:-

脊柱:1.63

網膜:-

目:-

動脈:3.42

静脈:-

リンパ節:3.72

末梢血:-

脾臓:3.51

胸腺:2.86

骨髄:-

脂肪:-

骨:3.28

皮膚:3.54

RNA-seq

大脳:1.15

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:13.80

前立腺:30.90

卵巣:-

精巣:29.60

心臓:18.60

骨格筋:-

食道:-

胃:32.70

腸:-

結腸:-

肝臓:27.20

肺:10

膀胱:-

腎臓:24.20

下垂体:38.80

甲状腺:-

副腎:-

膵臓:28.10

乳腺:29.40

唾液腺:-

GeneChip

子宮:8.09

胎盤:7.78

前立腺:8.11

卵巣:8.10

精巣:6.94

心臓:7.13

骨格筋:6.86

食道:-

胃:8.43

腸:9.13

結腸:-

肝臓:8.89

肺:8.70

膀胱:8.19

腎臓:8.39

下垂体:7.77

甲状腺:-

副腎:7.60

膵臓:7.99

乳腺:7.98

唾液腺:7.60

CAGE

子宮:3.21

胎盤:3.12

前立腺:3.08

卵巣:3.17

精巣:1.34

心臓:-

骨格筋:-

食道:-

胃:2.60

腸:3.43

結腸:3.66

肝臓:3.41

肺:3.46

膀胱:3.18

腎臓:-

下垂体:2.71

甲状腺:-

副腎:3.09

膵臓:3.27

乳腺:3.35

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.67

食道:-

胃:-

腸:-

結腸:-

肝臓:2.72

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_009068
Gene ID	19766
Unigene ID	Mm.374799
Probe set ID	1449485_at [Mouse430_2]
Ensembl ID	ENSMUSG00000021408

オーソログ対応遺伝子

ヒト[1]	NM_003804
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR000488	Death
IPR011029	DEATH-like
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0044257	cellular protein catabolic process
GO:0071356	cellular response to tumor necrosis factor
GO:0060555	induction of necroptosis by extracellular signals
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB cascade
GO:0016310	phosphorylation
GO:0043065	positive regulation of apoptosis
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0032757	positive regulation of interleukin-8 production
GO:0046330	positive regulation of JNK cascade
GO:0045651	positive regulation of macrophage differentiation
GO:0060545	positive regulation of necroptosis
GO:0010940	positive regulation of necrotic cell death
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0042327	positive regulation of phosphorylation
GO:0043068	positive regulation of programmed cell death
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0032760	positive regulation of tumor necrosis factor production
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0051291	protein heterooligomerization
GO:0051260	protein homooligomerization
GO:0070926	regulation of ATP:ADP antiporter activity
GO:0034612	response to tumor necrosis factor
GO:0007165	signal transduction
GO:0019048	virus-host interaction

Cellular Component

GO:0005737	cytoplasm
GO:0031264	death-inducing signaling complex
GO:0016020	membrane
GO:0045121	membrane raft
GO:0005739	mitochondrion
GO:0005886	plasma membrane
GO:0043234	protein complex
GO:0043235	receptor complex

Molecular Function

GO:0005524	ATP binding
GO:0070513	death domain binding
GO:0005123	death receptor binding
GO:0042802	identical protein binding
GO:0016301	kinase activity
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

receptor (TNFRSF)-interacting serine-threonine kinase 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function