sonic hedgehog

 詳細情報を見る

同義遺伝子名

9530036O11Rik, Sonic hedgehog protein precursor, HHG-1, Hhg1, sonic hedgehog, SHH, Shh, Dsh

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:5.20 小脳:- 脳幹:127.10 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:31.70
GeneChip 大脳:4.26 小脳:4.53 脳幹:- 脳梁:- 松果体:- 末梢神経:5.20 脊柱:4.78 網膜:4.12 目:4.37 動脈:- 静脈:4.10 リンパ節:4.15 末梢血:- 脾臓:4.20 胸腺:- 骨髄:4.23 脂肪:4.62 骨:4.14 皮膚:4.22
CAGE 大脳:0.86 小脳:- 脳幹:1.73 脳梁:- 松果体:- 末梢神経:- 脊柱:1.76 網膜:- 目:- 動脈:0 静脈:- リンパ節:0 末梢血:- 脾臓:0 胸腺:0.27 骨髄:- 脂肪:- 骨:0 皮膚:2.42
RNA-seq 大脳:1.62 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:- 前立腺:30.90 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:9.10        肺:50.20    膀胱:264.70 腎臓:- 下垂体:- 甲状腺:- 副腎:1273.30 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:4.06 胎盤:4.37 前立腺:4.68 卵巣:4.16 精巣:4.32 心臓:4.68 骨格筋:4.71 食道:- 胃:5.24 腸:4.28 結腸:- 肝臓:4.51 肺:4.86 膀胱:6.66 腎臓:4.48 下垂体:4.34 甲状腺:- 副腎:4.71 膵臓:5.17 乳腺:4.22 唾液腺:4.61
CAGE 子宮:0 胎盤:0 前立腺:2.39 卵巣:0.13 精巣:0 心臓:- 骨格筋:- 食道:- 胃:3.94 腸:0 結腸:0.23     肝臓:0.26    肺:1.73 膀胱:5.10 腎臓:- 下垂体:0 甲状腺:- 副腎:4.52 膵臓:0 乳腺:0 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:0.73 食道:- 胃:- 腸:- 結腸:-     肝臓:1.68        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_009170
Gene ID 20423
Unigene ID Mm.57202
Probe set ID 1427571_at  [Mouse430_2]
Ensembl ID ENSMUSG00000002633

オーソログ対応遺伝子

ヒト[1]  NM_000193
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

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Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0048856  anatomical structure development
GO:0048646  anatomical structure formation involved in morphogenesis
GO:0008209  androgen metabolic process
GO:0001525  angiogenesis
GO:0009952  anterior/posterior pattern formation
GO:0006915  apoptosis
GO:0060840  artery development
GO:0007411  axon guidance
GO:0060020  Bergmann glial cell differentiation
GO:0007596  blood coagulation
GO:0060441  branching involved in lung morphogenesis
GO:0060442  branching involved in prostate gland morphogenesis
GO:0060445  branching involved in salivary gland morphogenesis
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0048754  branching morphogenesis of a tube
GO:0060447  bud outgrowth involved in lung branching
GO:0043010  camera-type eye development
GO:0043369  CD4-positive or CD8-positive, alpha-beta T cell lineage commitment
GO:0007154  cell communication
GO:0008219  cell death
GO:0048468  cell development
GO:0045165  cell fate commitment
GO:0001708  cell fate specification
GO:0008283  cell proliferation
GO:0007267  cell-cell signaling
GO:0071285  cellular response to lithium ion
GO:0007417  central nervous system development
GO:0003140  determination of left/right asymmetry in lateral mesoderm
GO:0007368  determination of left/right symmetry
GO:0048589  developmental growth
GO:0048546  digestive tract morphogenesis
GO:0021904  dorsal/ventral neural tube patterning
GO:0009953  dorsal/ventral pattern formation
GO:0007398  ectoderm development
GO:0009790  embryonic development
GO:0048557  embryonic digestive tract morphogenesis
GO:0042733  embryonic digit morphogenesis
GO:0048617  embryonic foregut morphogenesis
GO:0035115  embryonic forelimb morphogenesis
GO:0035116  embryonic hindlimb morphogenesis
GO:0030326  embryonic limb morphogenesis
GO:0048598  embryonic morphogenesis
GO:0048568  embryonic organ development
GO:0048706  embryonic skeletal system development
GO:0006897  endocytosis
GO:0060664  epithelial cell proliferation involved in salivary gland morphogenesis
GO:0060684  epithelial-mesenchymal cell signaling
GO:0060738  epithelial-mesenchymal signaling involved in prostate gland development
GO:0030010  establishment of cell polarity
GO:0030900  forebrain development
GO:0048859  formation of anatomical boundary
GO:0007502  gut mesoderm development
GO:0001942  hair follicle development
GO:0031069  hair follicle morphogenesis
GO:0007507  heart development
GO:0001947  heart looping
GO:0030902  hindbrain development
GO:0007442  hindgut morphogenesis
GO:0048839  inner ear development
GO:0016539  intein-mediated protein splicing
GO:0045109  intermediate filament organization
GO:0001822  kidney development
GO:0060459  left lung development
GO:0060174  limb bud formation
GO:0060173  limb development
GO:0030324  lung development
GO:0060428  lung epithelium development
GO:0060463  lung lobe morphogenesis
GO:0060425  lung morphogenesis
GO:0060484  lung-associated mesenchyme development
GO:0002320  lymphoid progenitor cell differentiation
GO:0030539  male genitalia development
GO:0048808  male genitalia morphogenesis
GO:0010463  mesenchymal cell proliferation
GO:0060916  mesenchymal cell proliferation involved in lung development
GO:0060783  mesenchymal smoothened signaling pathway involved in prostate gland development
GO:0001656  metanephros development
GO:0030901  midbrain development
GO:0007275  multicellular organismal development
GO:0080125  multicellular structure septum development
GO:0045445  myoblast differentiation
GO:0014902  myotube differentiation
GO:0046639  negative regulation of alpha-beta T cell differentiation
GO:0043066  negative regulation of apoptosis
GO:0045596  negative regulation of cell differentiation
GO:0030336  negative regulation of cell migration
GO:0010629  negative regulation of gene expression
GO:0032435  negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0042177  negative regulation of protein catabolic process
GO:0034244  negative regulation of RNA elongation from RNA polymerase II promoter
GO:0042130  negative regulation of T cell proliferation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0030178  negative regulation of Wnt receptor signaling pathway
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0045060  negative thymic T cell selection
GO:0001755  neural crest cell migration
GO:0001841  neural tube formation
GO:0007405  neuroblast proliferation
GO:0048663  neuron fate commitment
GO:0042476  odontogenesis
GO:0042475  odontogenesis of dentine-containing tooth
GO:0014003  oligodendrocyte development
GO:0048709  oligodendrocyte differentiation
GO:0048645  organ formation
GO:0002076  osteoblast development
GO:0060021  palate development
GO:0031016  pancreas development
GO:0007389  pattern specification process
GO:0001569  patterning of blood vessels
GO:0046638  positive regulation of alpha-beta T cell differentiation
GO:0045597  positive regulation of cell differentiation
GO:0051781  positive regulation of cell division
GO:0008284  positive regulation of cell proliferation
GO:0060769  positive regulation of epithelial cell proliferation involved in prostate gland development
GO:0010628  positive regulation of gene expression
GO:0021940  positive regulation of granule cell precursor proliferation
GO:0007228  positive regulation of hh target transcription factor activity
GO:0033092  positive regulation of immature T cell proliferation in the thymus
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0002052  positive regulation of neuroblast proliferation
GO:0045666  positive regulation of neuron differentiation
GO:0048714  positive regulation of oligodendrocyte differentiation
GO:0070447  positive regulation of oligodendrocyte progenitor proliferation
GO:0060406  positive regulation of penile erection
GO:0046534  positive regulation of photoreceptor cell differentiation
GO:0042307  positive regulation of protein import into nucleus
GO:0014858  positive regulation of skeletal muscle cell proliferation
GO:0048643  positive regulation of skeletal muscle tissue development
GO:0045880  positive regulation of smoothened signaling pathway
GO:0051155  positive regulation of striated muscle cell differentiation
GO:0033089  positive regulation of T cell differentiation in the thymus
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0030177  positive regulation of Wnt receptor signaling pathway
GO:0045059  positive thymic T cell selection
GO:0060516  primary prostatic bud elongation
GO:0060523  prostate epithelial cord elongation
GO:0030850  prostate gland development
GO:0060513  prostatic bud formation
GO:0034504  protein localization in nucleus
GO:0006508  proteolysis
GO:0042127  regulation of cell proliferation
GO:0060768  regulation of epithelial cell proliferation involved in prostate gland development
GO:0010468  regulation of gene expression
GO:0060782  regulation of mesenchymal cell proliferation involved in prostate gland development
GO:0042481  regulation of odontogenesis
GO:0060685  regulation of prostatic bud formation
GO:0030162  regulation of proteolysis
GO:0006355  regulation of transcription, DNA-dependent
GO:0030323  respiratory tube development
GO:0048678  response to axon injury
GO:0045471  response to ethanol
GO:0060458  right lung development
GO:0060662  salivary gland cavitation
GO:0007165  signal transduction
GO:0043588  skin development
GO:0007224  smoothened signaling pathway
GO:0021938  smoothened signaling pathway involved in regulation of granule cell precursor cell proliferation
GO:0021513  spinal cord dorsal/ventral patterning
GO:0021522  spinal cord motor neuron differentiation
GO:0048864  stem cell development
GO:0051146  striated muscle cell differentiation
GO:0014706  striated muscle tissue development
GO:0033077  T cell differentiation in the thymus
GO:0021978  telencephalon regionalization
GO:0021794  thalamus development
GO:0048538  thymus development
GO:0030878  thyroid gland development
GO:0043586  tongue development
GO:0043587  tongue morphogenesis
GO:0060438  trachea development
GO:0060439  trachea morphogenesis
GO:0001944  vasculature development
GO:0001570  vasculogenesis
GO:0060979  vasculogenesis involved in coronary vascular morphogenesis
GO:0021521  ventral spinal cord interneuron specification
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0030424  axon
GO:0043025  cell soma
GO:0009986  cell surface
GO:0030425  dendrite
GO:0005783  endoplasmic reticulum
GO:0031012  extracellular matrix
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005794  Golgi apparatus
GO:0016020  membrane
GO:0045121  membrane raft
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0030133  transport vesicle

Molecular Function

GO:0005509  calcium ion binding
GO:0001948  glycoprotein binding
GO:0005539  glycosaminoglycan binding
GO:0016787  hydrolase activity
GO:0043237  laminin-1 binding
GO:0005113  patched binding
GO:0008233  peptidase activity
GO:0005515  protein binding
GO:0004871  signal transducer activity
GO:0008270  zinc ion binding