superoxide dismutase 2, mitochondrial

詳細情報を見る

同義遺伝子名

manganese superoxide dismutase, superoxide dismutase 2, mitochondrial, MnSOD, Sod-2, Superoxide dismutase [Mn], mitochondrial precursor, Sod2, manganese SOD, MGC6144

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:166.70 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:47.30 網膜:128.60 目:60.80 動脈:- 静脈:- リンパ節:21.60 末梢血:57.50 脾臓:26.30 胸腺:- 骨髄:628.30 脂肪:- 骨:150.30 皮膚:118.80
GeneChip 大脳:9.80 小脳:9.72 脳幹:- 脳梁:- 松果体:- 末梢神経:10.10 脊柱:10.07 網膜:9.16 目:9.50 動脈:- 静脈:9.29 リンパ節:9.63 末梢血:- 脾臓:9.04 胸腺:- 骨髄:9.60 脂肪:11.73 骨:9.74 皮膚:9.60
CAGE 大脳:5.40 小脳:- 脳幹:5.73 脳梁:- 松果体:- 末梢神経:- 脊柱:5.64 網膜:- 目:- 動脈:6.97 静脈:- リンパ節:4.59 末梢血:- 脾臓:4.80 胸腺:4.63 骨髄:- 脂肪:- 骨:5.13 皮膚:4.94
RNA-seq 大脳:20.41 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:87.20 胎盤:55.20 前立腺:61.80 卵巣:11.50 精巣:170 心臓:390.60 骨格筋:106.50 食道:- 胃:229.10 腸:37 結腸:52.90     肝臓:135.80        肺:60.30    膀胱:132.40 腎臓:112.80 下垂体:193.80 甲状腺:- 副腎:- 膵臓:131.40 乳腺:39.20 唾液腺:108
GeneChip 子宮:9.52 胎盤:8.99 前立腺:11.08 卵巣:10.36 精巣:10.75 心臓:12.64 骨格筋:11.61 食道:- 胃:11.13 腸:10.28 結腸:- 肝臓:11.58 肺:10.13 膀胱:10.14 腎臓:12.08 下垂体:10.33 甲状腺:- 副腎:11.25 膵臓:9.90 乳腺:11.14 唾液腺:10.94
CAGE 子宮:4.73 胎盤:4.45 前立腺:5.57 卵巣:4.89 精巣:5.36 心臓:- 骨格筋:- 食道:- 胃:5.99 腸:5.32 結腸:5.17     肝臓:6.43    肺:5.21 膀胱:5.12 腎臓:- 下垂体:5.19 甲状腺:- 副腎:5.42 膵臓:5.22 乳腺:5.62 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:46.29 食道:- 胃:- 腸:- 結腸:-     肝臓:47.92        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_013671
Gene ID 20656
Unigene ID Mm.290876
Probe set ID 1417193_at  [Mouse430_2]
Ensembl ID ENSMUSG00000006818

オーソログ対応遺伝子

ヒト[8]  NM_000636, NM_001024465, NM_001024466
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1612602
1799792
1845916
1936961
2076813
2901401
3003932
3082971
3797253
4358964
6816725
6860298
7063884
7333654
7350646
7493016
7578676
7613035
7875582
8268651
8406027
8720919
8790408
8792216
8835526
8889548
9096116
9264557
9268631
9372929
9398854
9412501
9462746
9533942
9582437
9651187
9724058
9774481
9788901
9819222
9927656
10030845
10049502
10212301
10349636
10421798
10598322
10672232
10699751
10762155
10927183
11042159
11076861
11156968
11217851
11226230
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11304553
11507057
11514315
11527927
11583975
11595386
11606622
11641723
11677043
11796207
11861570
11864929
12032821
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12126755
12176043
12383507
12385642
12459471
12466851
12477932
12527430
12646716
12700280
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12919935
12931191
12934715
14610273
14651853
14679299
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14684357
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15075214
15083518
15147524
15166009
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15184255
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15650415
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15721992
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20156551
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23195678
23213199
23219873
23237540
23360182
23580200
23624625
23792772
23862693
23872067
23997094
24068327
24135141
24191052
24218554
24225087
24308935
24500690
24565075

遺伝子オントロジー  (GO ID)

Biological Process

GO:0001306  age-dependent response to oxidative stress
GO:0001315  age-dependent response to reactive oxygen species
GO:0008637  apoptotic mitochondrial changes
GO:0003032  detection of oxygen
GO:0008630  DNA damage response, signal transduction resulting in induction of apoptosis
GO:0048773  erythrophore differentiation
GO:0006749  glutathione metabolic process
GO:0007507  heart development
GO:0030097  hemopoiesis
GO:0050665  hydrogen peroxide biosynthetic process
GO:0042743  hydrogen peroxide metabolic process
GO:0008631  induction of apoptosis by oxidative stress
GO:0055072  iron ion homeostasis
GO:0001889  liver development
GO:0007626  locomotory behavior
GO:0007005  mitochondrion organization
GO:0043066  negative regulation of apoptosis
GO:0008285  negative regulation of cell proliferation
GO:0045599  negative regulation of fat cell differentiation
GO:0048147  negative regulation of fibroblast proliferation
GO:0043524  negative regulation of neuron apoptosis
GO:0048666  neuron development
GO:0055114  oxidation reduction
GO:0032364  oxygen homeostasis
GO:0045429  positive regulation of nitric oxide biosynthetic process
GO:0009791  post-embryonic development
GO:0051260  protein homooligomerization
GO:0051289  protein homotetramerization
GO:0008217  regulation of blood pressure
GO:0050790  regulation of catalytic activity
GO:0051881  regulation of mitochondrial membrane potential
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0001836  release of cytochrome c from mitochondria
GO:0019430  removal of superoxide radicals
GO:0022904  respiratory electron transport chain
GO:0014823  response to activity
GO:0048678  response to axon injury
GO:0042493  response to drug
GO:0010332  response to gamma radiation
GO:0042542  response to hydrogen peroxide
GO:0055093  response to hyperoxia
GO:0031667  response to nutrient levels
GO:0006979  response to oxidative stress
GO:0000302  response to reactive oxygen species
GO:0006950  response to stress
GO:0000303  response to superoxide
GO:0007605  sensory perception of sound
GO:0042554  superoxide anion generation
GO:0006801  superoxide metabolic process
GO:0042311  vasodilation
GO:0003069  vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure

Cellular Component

GO:0005737  cytoplasm
GO:0005743  mitochondrial inner membrane
GO:0042645  mitochondrial nucleoid
GO:0005739  mitochondrion

Molecular Function

GO:0003677  DNA binding
GO:0042802  identical protein binding
GO:0030145  manganese ion binding
GO:0046872  metal ion binding
GO:0016491  oxidoreductase activity
GO:0019825  oxygen binding
GO:0005515  protein binding
GO:0004784  superoxide dismutase activity