serine (or cysteine) peptidase inhibitor, clade E, member 2

詳細情報を見る

同義遺伝子名

nexin, GDN, Pi7, Serine protease-inhibitor 4, Protease nexin I, protease nexin 1, Glia-derived nexin precursor, PAI-1, Pn1, Serpine2, B230326M24Rik, PN-1, Spi4, PI7

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:11.91 小脳:10.82 脳幹:- 脳梁:- 松果体:- 末梢神経:10.88 脊柱:12.13 網膜:8.90 目:8.73 動脈:- 静脈:10.91 リンパ節:7 末梢血:- 脾臓:8.16 胸腺:- 骨髄:11.62 脂肪:9.67 骨:12.37 皮膚:9.96
CAGE 大脳:4.41 小脳:- 脳幹:5.25 脳梁:- 松果体:- 末梢神経:- 脊柱:5.36 網膜:- 目:- 動脈:4.56 静脈:- リンパ節:1.35 末梢血:- 脾臓:2.26 胸腺:3.07 骨髄:- 脂肪:- 骨:5.44 皮膚:3.57
RNA-seq 大脳:41.44 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST nodata
GeneChip 子宮:10.29 胎盤:12.10 前立腺:10.19 卵巣:12.43 精巣:5.47 心臓:9.32 骨格筋:11.61 食道:- 胃:7.64 腸:7.83 結腸:- 肝臓:7.97 肺:11.35 膀胱:9.22 腎臓:8.25 下垂体:10.99 甲状腺:- 副腎:8.47 膵臓:9.19 乳腺:9.53 唾液腺:9.29
CAGE 子宮:3.41 胎盤:4.74 前立腺:5.61 卵巣:5.47 精巣:0 心臓:- 骨格筋:- 食道:- 胃:2.90 腸:1.22 結腸:1.63     肝臓:1.80    肺:4.41 膀胱:3.33 腎臓:- 下垂体:3.86 甲状腺:- 副腎:2.47 膵臓:3.32 乳腺:1.56 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:17.58 食道:- 胃:- 腸:- 結腸:-     肝臓:1.80        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007596  blood coagulation
GO:0030154  cell differentiation
GO:0021683  cerebellar granular layer morphogenesis
GO:0050974  detection of mechanical stimulus involved in sensory perception
GO:0060384  innervation
GO:0060291  long-term synaptic potentiation
GO:0042628  mating plug formation
GO:0007275  multicellular organismal development
GO:0030195  negative regulation of blood coagulation
GO:0030308  negative regulation of cell growth
GO:0008285  negative regulation of cell proliferation
GO:0010951  negative regulation of endopeptidase activity
GO:0010466  negative regulation of peptidase activity
GO:0014067  negative regulation of phosphoinositide 3-kinase cascade
GO:0010757  negative regulation of plasminogen activation
GO:0010544  negative regulation of platelet activation
GO:0042177  negative regulation of protein catabolic process
GO:0010955  negative regulation of protein maturation by peptide bond cleavage
GO:0045861  negative regulation of proteolysis
GO:0045879  negative regulation of smoothened signaling pathway
GO:0010766  negative regulation of sodium ion transport
GO:0007399  nervous system development
GO:0048711  positive regulation of astrocyte differentiation
GO:0010976  positive regulation of neuron projection development
GO:0051966  regulation of synaptic transmission, glutamatergic
GO:0048505  regulation of timing of cell differentiation
GO:0009611  response to wounding
GO:0032940  secretion by cell
GO:0033363  secretory granule organization

Cellular Component

GO:0043025  cell soma
GO:0005829  cytosol
GO:0031012  extracellular matrix
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0031232  extrinsic to external side of plasma membrane
GO:0016020  membrane
GO:0031594  neuromuscular junction
GO:0031091  platelet alpha granule

Molecular Function

GO:0005539  glycosaminoglycan binding
GO:0008201  heparin binding
GO:0030414  peptidase inhibitor activity
GO:0005102  receptor binding
GO:0004867  serine-type endopeptidase inhibitor activity