sterol regulatory element binding transcription factor 1

詳細情報を見る

同義遺伝子名

Sterol regulatory element-binding protein 1, ADD1, Srebf1, SREBP1, SREBP-1c, SREBP-1, D630008H06, ADD-1, Srebp1, SREBP-1a, sterol regulatory element binding factor 1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:8.20 小脳:7.95 脳幹:- 脳梁:- 松果体:- 末梢神経:9.10 脊柱:8.96 網膜:9.71 目:10.03 動脈:- 静脈:8.26 リンパ節:9.08 末梢血:- 脾臓:8.79 胸腺:- 骨髄:8.40 脂肪:10.75 骨:8.05 皮膚:9.18
CAGE 大脳:3.74 小脳:- 脳幹:4.22 脳梁:- 松果体:- 末梢神経:- 脊柱:4.43 網膜:- 目:- 動脈:5.49 静脈:- リンパ節:3.63 末梢血:- 脾臓:3.59 胸腺:4.22 骨髄:- 脂肪:- 骨:3.64 皮膚:4.49
RNA-seq 大脳:9.54 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST nodata
GeneChip 子宮:8.92 胎盤:8.77 前立腺:9.43 卵巣:9.52 精巣:6.93 心臓:8.43 骨格筋:9.48 食道:- 胃:8.84 腸:8.94 結腸:- 肝臓:10.05 肺:9.44 膀胱:10.17 腎臓:8.45 下垂体:9.41 甲状腺:- 副腎:9.71 膵臓:8.65 乳腺:10.08 唾液腺:10.26
CAGE 子宮:3.69 胎盤:3.94 前立腺:4.14 卵巣:3.93 精巣:1.60 心臓:- 骨格筋:- 食道:- 胃:3.59 腸:6.02 結腸:3.75     肝臓:6.65    肺:4.15 膀胱:5.02 腎臓:- 下垂体:4.27 甲状腺:- 副腎:4.59 膵臓:4.86 乳腺:6.10 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:7.56 食道:- 胃:- 腸:- 結腸:-     肝臓:22.22        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_011480
Gene ID 20787
Unigene ID -
Probe set ID 1426690_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000020538

オーソログ対応遺伝子

ヒト[2]  NM_001005291, NM_004176
ラット[2]  NM_001005291, NM_004176

染色体

-

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8827514
8833906
8889548
9062340
9329978
9337407
9890958
10049592
10052151
10064584
10349636
10514488
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12466851
12477932
12520002
12576519
12736163
12855691
12897148
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12975478
14512514
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14633850
14654692
14662765
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14722127
14755333
14985341
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15037635
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15123650
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23999723
24379443
24398675
24425205
24606891
24606892

遺伝子オントロジー  (GO ID)

Biological Process

GO:0009267  cellular response to starvation
GO:0008203  cholesterol metabolic process
GO:0008286  insulin receptor signaling pathway
GO:0008610  lipid biosynthetic process
GO:0006629  lipid metabolic process
GO:0046676  negative regulation of insulin secretion
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045542  positive regulation of cholesterol biosynthetic process
GO:0045723  positive regulation of fatty acid biosynthetic process
GO:0031065  positive regulation of histone deacetylation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0010867  positive regulation of triglyceride biosynthetic process
GO:0019217  regulation of fatty acid metabolic process
GO:0003062  regulation of heart rate by chemical signal
GO:0050796  regulation of insulin secretion
GO:0006355  regulation of transcription, DNA-dependent
GO:0009749  response to glucose stimulus
GO:0008202  steroid metabolic process
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0044444  cytoplasmic part
GO:0031410  cytoplasmic vesicle
GO:0005783  endoplasmic reticulum
GO:0005794  Golgi apparatus
GO:0016021  integral to membrane
GO:0043231  intracellular membrane-bounded organelle
GO:0016020  membrane
GO:0005634  nucleus
GO:0043234  protein complex

Molecular Function

GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0046983  protein dimerization activity
GO:0019901  protein kinase binding
GO:0043565  sequence-specific DNA binding
GO:0032810  sterol response element binding
GO:0003700  transcription factor activity