signal transducer and activator of transcription 1

 詳細情報を見る

同義遺伝子名

AA408197, 2010005J02Rik, signal transducer and activator of transcription 1, Signal transducer and activator of transcription 1, Stat1

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:38.20 小脳:55.30 脳幹:31.80 脳梁:- 松果体:- 末梢神経:38.20 脊柱:141.90 網膜:32.10 目:91.20 動脈:337.60 静脈:- リンパ節:43.20 末梢血:762 脾臓:368.70 胸腺:177.80 骨髄:76.90 脂肪:212.70 骨:137.80 皮膚:63.30
GeneChip 大脳:6.99 小脳:7.52 脳幹:- 脳梁:- 松果体:- 末梢神経:8.41 脊柱:7.65 網膜:5.89 目:7.06 動脈:- 静脈:7.20 リンパ節:12.03 末梢血:- 脾臓:11.89 胸腺:- 骨髄:10.32 脂肪:9.58 骨:9.64 皮膚:8.30
CAGE 大脳:2.56 小脳:- 脳幹:2.64 脳梁:- 松果体:- 末梢神経:- 脊柱:2.88 網膜:- 目:- 動脈:4.70 静脈:- リンパ節:5.89 末梢血:- 脾臓:4.79 胸腺:4.69 骨髄:- 脂肪:- 骨:4.17 皮膚:3.05
RNA-seq 大脳:2.40 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:43.60 胎盤:165.70 前立腺:- 卵巣:- 精巣:44.30 心臓:- 骨格筋:- 食道:- 胃:- 腸:147.90 結腸:88.10     肝臓:18.10        肺:472    膀胱:- 腎臓:64.50 下垂体:25.80 甲状腺:- 副腎:1273.30 膵臓:18.80 乳腺:238.30 唾液腺:-
GeneChip 子宮:10.16 胎盤:9.08 前立腺:8.31 卵巣:9.46 精巣:7.78 心臓:8.95 骨格筋:8.48 食道:- 胃:8.66 腸:9.83 結腸:- 肝臓:10.04 肺:10.02 膀胱:8.84 腎臓:8.81 下垂体:8.41 甲状腺:- 副腎:9.23 膵臓:7.21 乳腺:9.80 唾液腺:8.34
CAGE 子宮:4.25 胎盤:3.93 前立腺:2.90 卵巣:3.61 精巣:2.30 心臓:- 骨格筋:- 食道:- 胃:3.42 腸:4.09 結腸:4.60     肝臓:4.14    肺:4.67 膀胱:3.67 腎臓:- 下垂体:3.23 甲状腺:- 副腎:4.58 膵臓:3.04 乳腺:3.74 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.82 食道:- 胃:- 腸:- 結腸:-     肝臓:4.38        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_009283
Gene ID 20846
Unigene ID Mm.277406
Probe set ID 1450033_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000026104

オーソログ対応遺伝子

ヒト[8]  NM_007315, NM_139266
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7490523
7515712
7545930
7567467
7579387
8140422
8530075
8593242
8608597
8608598
8626752
8631837
8675207
8805627
8833906
9022056
9069288
9092506
9119818
9126479
9229117
9287210
9342212
9548487
9638363
9695817
9828143
9846495
9887329
10200816
10349636
10364154
10364426
10510345
10526573
10562320
10629051
10640742
10692450
10754318
10781830
10817963
10851046
10851049
10851050
10851062
10865997
10867663
10899912
10946258
11034357
11042159
11076861
11086033
11163195
11217851
11310846
11323675
11371356
11390995
11493533
11544199
11554754
11579100
11881154
11884466
11884587
11932417
11971185
11972023
12006410
12006974
12007403
12018856
12033784
12138178
12162464
12167251
12171910
12198138
12219085
12223448
12232043
12270932
12364588
12370359
12407025
12426001
12426389
12438372
12438448
12441126
12444163
12461178
12466851
12477932
12520002
12526039
12551969
12624267
12634107
12671680
12679810
12686553
12727921
12730885
12811839
12816762
12832402
12859963
12865406
12872135
12923053
12925694
12957148
12960068
14522949
14600148
14602726
14617019
14656722
14657353
14662340
14662881
14670297
14688355
14699080
14730360
14732359
14733929
14734769
14738323
14764699
14871928
14976252
14977926
14978477
15020428
15073186
15128825
15188379
15189833
15213094
15226272
15238607
15240659
15240691
15240699
15246962
15322115
15356124
15356135
15452265
15477229
15485925
15491990
15522878
15537876
15539157
15541348
15585884
15618518
15634877
15661922
15713743
15719366
15761153
15778340
15784679
15814715
15850655
15851485
15852015
15905519
15905569
15919828
15919906
15956575
15963787
15964802
15972639
15983048
16014513
16024814
16046307
16081786
16116224
16141072
16141073
16148142
16148148
16200070
16210330
16210337
16251407
16254350
16260600
16260741
16284791
16301649
16315087
16365415
16388483
16424049
16472772
16482512
16493033
16507120
16514065
16563502
16585592
16602821
16618773
16634641
16670015
16670771
16688530
16689660
16709859
16709865
16709871
16717119
16728283
16731906
16734559
16751369
16764725
16782051
16785492
16785566
16843267
16857984
16878149
16906167
16951379
17015705
17015727
17018853
17032168
17065231
17078933
17082570
17114459
17121994
17133483
17170125
17182557
17200147
17218386
17227866
17229692
17234735
17237438
17293456
17307940
17346710
17424888
17473223
17475277
17490433
17507688
17513775
17533179
17548600
17548649
17549733
17553874
17575072
17620422
17634555
17661345
17683066
17689680
17785781
17785783
17823504
17846149
17849321
17898865
17908914
17938255
17950290
17981810
17994023
18023015
18026101
18059273
18060035
18061568
18083102
18096999
18156621
18158321
18178823
18209032
18211965
18227389
18250422
18268032
18274639
18287094
18287559
18292557
18322213
18322222
18329552
18340381
18341989
18354215
18378670
18400863
18424890
18431520
18467446
18493980
18496526
18499741
18523269
18551195
18574148
18606672
18607004
18625883
18641358
18652890
18656624
18682602
18713987
18771758
18774582
18799693
18806225
18818378
18923003
18941537
18954557
18981230
19001470
19009526
19018808
19075017
19109391
19164812
19185844
19201901
19224984
19230833
19231233
19246642
19272190
19325004
19337996
19349465
19352584
19380776
19387591
19439086
19494319
19501566
19502390
19503789
19508864
19521500
19528464
19542364
19564349
19587017
19620279
19620292
19622834
19641143
19647793
19703987
19741297
19783024
19786532
19889125
19890039
19890042
19923465
19924240
19949064
20059953
20089923
20123960
20123961
20190134
20211142
20217138
20299783
20347693
20348925
20372968
20386712
20407011
20412781
20427527
20428250
20436908
20483775
20562259
20585034
20592027
20637658
20637660
20648647
20699362
20702617
20713887
20739514
20850013
20887958
20889505
20932939
20974984
21039465
21041726
21076615
21098093
21124930
21125645
21172865
21224412
21239708
21248711
21257966
21267068
21294722
21349431
21372127
21376308
21379341
21383241
21447043
21536945
21551362
21553074
21572044
21606371
21624938
21633090
21636857
21670504
21674475
21677750
21684247
21709156
21723864
21778271
21828128
21833847
21835648
21876033
21915277
21937453
21937652
21943709
21949815
21984703
21987655
21994441
22003092
22005305
22065572
22072963
22114338
22185785
22210911
22246627
22264274
22268122
22305621
22306691
22337873
22412192
22427680
22438254
22450807
22454431
22467218
22474018
22479645
22496215
22510411
22536153
22560297
22561605
22562203
22649549
22713837
22719255
22726954
22745821
22769061
22777121
22784990
22785228
22805310
22808166
22837198
22837488
22865856
22892029
22902832
22925810
22942432
22951832
22956547
22960221
22968462
22981537
22984078
23038263
23041519
23125412
23125414
23188796
23213481
23254377
23273843
23278812
23321674
23335749
23349024
23352233
23376950
23401241
23407880
23435120
23440417
23447690
23479229
23486482
23527309
23543757
23554911
23582260
23597922
23630250
23644631
23653476
23670194
23686490
23728775
23733873
23749757
23798382
23843024
23903655
23903830
23904165
23933255
23958683
24069548
24216477
24360797
24367096
24413774
24449862
24489092
24503098
24619410
24911587

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0008015  blood circulation
GO:0032869  cellular response to insulin stimulus
GO:0019221  cytokine-mediated signaling pathway
GO:0006917  induction of apoptosis
GO:0060333  interferon-gamma-mediated signaling pathway
GO:0007259  JAK-STAT cascade
GO:0031663  lipopolysaccharide-mediated signaling pathway
GO:0016525  negative regulation of angiogenesis
GO:0001937  negative regulation of endothelial cell proliferation
GO:0043124  negative regulation of I-kappaB kinase/NF-kappaB cascade
GO:0008284  positive regulation of cell proliferation
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0006355  regulation of transcription, DNA-dependent
GO:0009617  response to bacterium
GO:0051591  response to cAMP
GO:0034097  response to cytokine stimulus
GO:0042493  response to drug
GO:0043330  response to exogenous dsRNA
GO:0032496  response to lipopolysaccharide
GO:0009612  response to mechanical stimulus
GO:0007584  response to nutrient
GO:0043434  response to peptide hormone stimulus
GO:0007165  signal transduction
GO:0006351  transcription, DNA-dependent
GO:0033209  tumor necrosis factor-mediated signaling pathway
GO:0060337  type I interferon-mediated signaling pathway

Cellular Component

GO:0030424  axon
GO:0005737  cytoplasm
GO:0030425  dendrite
GO:0000790  nuclear chromatin
GO:0005634  nucleus

Molecular Function

GO:0005509  calcium ion binding
GO:0031730  CCR5 chemokine receptor binding
GO:0003677  DNA binding
GO:0003690  double-stranded DNA binding
GO:0019899  enzyme binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0043565  sequence-specific DNA binding
GO:0004871  signal transducer activity
GO:0003700  transcription factor activity
GO:0005164  tumor necrosis factor receptor binding