T-cell acute lymphocytic leukemia 1

詳細情報を見る

同義遺伝子名

Stem cell protein, Tal-1, Scl, Tal1, SCL/tal-1, T-cell acute lymphocytic leukemia 1, tal-1, TAL-1 protein

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:8.70 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:54 末梢血:28.80 脾臓:- 胸腺:- 骨髄:12.80 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:4.42 小脳:4.28 脳幹:- 脳梁:- 松果体:- 末梢神経:4.30 脊柱:4.92 網膜:4.19 目:4.44 動脈:- 静脈:5.23 リンパ節:5.42 末梢血:- 脾臓:6.93 胸腺:- 骨髄:10.85 脂肪:4.70 骨:10.06 皮膚:4.67
CAGE 大脳:0.48 小脳:- 脳幹:1.35 脳梁:- 松果体:- 末梢神経:- 脊柱:0.91 網膜:- 目:- 動脈:1.59 静脈:- リンパ節:1.28 末梢血:- 脾臓:5.23 胸腺:0 骨髄:- 脂肪:- 骨:4.50 皮膚:0.97
RNA-seq 大脳:1.03 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:22.20 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:9.10        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:3.30 唾液腺:-
GeneChip 子宮:4.77 胎盤:4.44 前立腺:4.58 卵巣:4.68 精巣:4.11 心臓:5.61 骨格筋:4.75 食道:- 胃:4.45 腸:4.37 結腸:- 肝臓:4.90 肺:7 膀胱:4.75 腎臓:4.61 下垂体:4.23 甲状腺:- 副腎:4.84 膵臓:4.50 乳腺:4.59 唾液腺:4.56
CAGE 子宮:1.10 胎盤:1.18 前立腺:0.37 卵巣:0.76 精巣:0 心臓:- 骨格筋:- 食道:- 胃:0.67 腸:0.72 結腸:0.23     肝臓:0.47    肺:2.38 膀胱:0.93 腎臓:- 下垂体:0.70 甲状腺:- 副腎:0.91 膵臓:0.84 乳腺:0.69 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.12 食道:- 胃:- 腸:- 結腸:-     肝臓:1.68        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_011527
Gene ID 21349
Unigene ID Mm.439685
Probe set ID 1449389_at  [Mouse430_2]
Ensembl ID ENSMUSG00000028717

オーソログ対応遺伝子

ヒト[2]  NM_003189
ラット[1]  NM_001107958

染色体

-

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0060018  astrocyte fate commitment
GO:0030154  cell differentiation
GO:0045165  cell fate commitment
GO:0060216  definitive hemopoiesis
GO:0035162  embryonic hemopoiesis
GO:0030218  erythrocyte differentiation
GO:0043249  erythrocyte maturation
GO:0048699  generation of neurons
GO:0060217  hemangioblast cell differentiation
GO:0030097  hemopoiesis
GO:0060218  hemopoietic stem cell differentiation
GO:0007626  locomotory behavior
GO:0030219  megakaryocyte differentiation
GO:0007275  multicellular organismal development
GO:0030099  myeloid cell differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0030182  neuron differentiation
GO:0030220  platelet formation
GO:0051781  positive regulation of cell division
GO:0045799  positive regulation of chromatin assembly or disassembly
GO:0045648  positive regulation of erythrocyte differentiation
GO:0045931  positive regulation of mitotic cell cycle
GO:0031334  positive regulation of protein complex assembly
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0042127  regulation of cell proliferation
GO:0060375  regulation of mast cell differentiation
GO:0045637  regulation of myeloid cell differentiation
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0021527  spinal cord association neuron differentiation
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0000118  histone deacetylase complex
GO:0033193  Lsd1/2 complex
GO:0000790  nuclear chromatin
GO:0005634  nucleus
GO:0043234  protein complex
GO:0005667  transcription factor complex

Molecular Function

GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0070888  E-box binding
GO:0019899  enzyme binding
GO:0042826  histone deacetylase binding
GO:0005515  protein binding
GO:0046983  protein dimerization activity
GO:0046982  protein heterodimerization activity
GO:0003700  transcription factor activity