transcription factor 3

詳細情報を見る

同義遺伝子名

E12, Transcription factor 3, AA408400, E47, Transcription factor E2-alpha, Alf2, Immunoglobulin enhancer-binding factor E12/E47, Transcription factor A1, VDIR, ALF2, transcription factor E2a, Tcfe2a, ME2, Tcf3, TCF-3, TCF3, Me2, Pan1, E12/E47, AW209082, E2A, Pan2

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:39.90 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:45.60 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:39.50 胸腺:9.90 骨髄:- 脂肪:- 骨:12.50 皮膚:23.80
GeneChip 大脳:7.24 小脳:7.30 脳幹:- 脳梁:- 松果体:- 末梢神経:6.82 脊柱:7.44 網膜:6.39 目:7.06 動脈:- 静脈:8.09 リンパ節:9.81 末梢血:- 脾臓:10.06 胸腺:- 骨髄:10.05 脂肪:7.62 骨:9.35 皮膚:8.01
CAGE 大脳:2.81 小脳:- 脳幹:2.73 脳梁:- 松果体:- 末梢神経:- 脊柱:2.77 網膜:- 目:- 動脈:3.16 静脈:- リンパ節:3.82 末梢血:- 脾臓:4.74 胸腺:4.34 骨髄:- 脂肪:- 骨:4.26 皮膚:3.98
RNA-seq 大脳:3.19 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:11.50 精巣:22.20 心臓:37.20 骨格筋:- 食道:- 胃:- 腸:- 結腸:17.60     肝臓:27.20        肺:20.10    膀胱:- 腎臓:24.20 下垂体:116.30 甲状腺:- 副腎:- 膵臓:- 乳腺:49 唾液腺:-
GeneChip 子宮:9.49 胎盤:7.25 前立腺:7.84 卵巣:9.29 精巣:7.47 心臓:7.61 骨格筋:7.73 食道:- 胃:7.56 腸:8.27 結腸:- 肝臓:7.06 肺:8.57 膀胱:7.58 腎臓:7.40 下垂体:8.04 甲状腺:- 副腎:8.64 膵臓:6.91 乳腺:8.03 唾液腺:7.65
CAGE 子宮:3.76 胎盤:3.06 前立腺:2.89 卵巣:3.75 精巣:2.68 心臓:- 骨格筋:- 食道:- 胃:3.32 腸:3.78 結腸:3.71     肝臓:2.93    肺:3.65 膀胱:3.44 腎臓:- 下垂体:2.91 甲状腺:- 副腎:3.40 膵臓:2.83 乳腺:3.30 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.42 食道:- 胃:- 腸:- 結腸:-     肝臓:2.24        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_001164153
Gene ID 21423
Unigene ID Mm.340601
Probe set ID 1426297_at  [Mouse430_2]
Ensembl ID ENSMUSG00000020167

オーソログ対応遺伝子

ヒト[14]  NM_001136139, NM_003200
ラット[3]  NM_001035237, NM_133524

染色体

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1321336
1465450
2160325
2181401
2503252
7542362
7589808
7662963
7784173
7875598
8001124
8001125
8104101
8112613
8163208
8211130
8479911
8649400
8654934
8759016
8760303
8900141
8948587
8999959
9047236
9050988
9184158
9234734
9343420
9372963
9409784
9545521
9584174
9676199
9892611
10330184
10349636
10373552
10435576
10454582
10512203
10587351
10922068
10924525
10961893
10984455
11042159
11076861
11217851
11224524
11309385
11318877
11404013
11439353
11447261
11591653
11711431
11782430
11784080
11812799
11820794
11869689
11937548
12070084
12172006
12200424
12217327
12297495
12370314
12415115
12435739
12466851
12477932
12482503
12517933
12520002
12566462
12657651
12700059
12714241
12717431
12904583
14573534
14576336
14610273
14685278
14697510
14757642
14764681
15016815
15027899
15030778
15037012
15044608
15078898
15104122
15159407
15193261
15210745
15226823
15280210
15280352
15310760
15314159
15322112
15351717
15361869
15456869
15489334
15509787
15520228
15572127
15618518
15655114
15719023
15782199
15800025
15840001
15934135
15967678
16005295
16007160
16140986
16141072
16141073
16272318
16315099
16365147
16407974
16412423
16428437
16449526
16602821
16648472
16682500
16709844
16888011
16971476
17018611
17082585
17108004
17316599
17339447
17430895
17442955
17452521
17551956
17617583
17623011
17652084
17878293
17938243
18069799
18093538
18093539
18184866
18195039
18209066
18214987
18287559
18353974
18384878
18388149
18523151
18538592
18550854
18552207
18557763
18565209
18669923
18674933
18799693
18927439
18941177
18958875
19011221
19122139
19181846
19272376
19295128
19323994
19345119
19399691
19428458
19451188
19553523
19591821
19592096
19605688
19718027
19734904
19741146
19752184
19796622
19799863
19801649
19822014
19828133
19833765
19946273
20006604
20022378
20059953
20062079
20144608
20154672
20211142
20219523
20359476
20498046
20826759
21131965
21241451
21267068
21273306
21325057
21421735
21453680
21610693
21677750
21685889
21685894
21694721
21730189
21775418
21857655
21935611
21972416
22007134
22057288
22169041
22270545
22354994
22425249
22514271
22561756
22564414
22573616
22581853
22585759
22674256
22829926
22972921
23159226
23297135
23536629
23658527
23752615
23824573
23851690
24078629
24123680
24259504
24379125
24470501
24470503
24747958

遺伝子オントロジー  (GO ID)

Biological Process

GO:0002326  B cell lineage commitment
GO:0048468  cell development
GO:0030154  cell differentiation
GO:0000080  G1 phase of mitotic cell cycle
GO:0043966  histone H3 acetylation
GO:0043967  histone H4 acetylation
GO:0033152  immunoglobulin V(D)J recombination
GO:0030098  lymphocyte differentiation
GO:0001779  natural killer cell differentiation
GO:0007399  nervous system development
GO:0048541  Peyer's patch development
GO:0030890  positive regulation of B cell proliferation
GO:0045787  positive regulation of cell cycle
GO:0010628  positive regulation of gene expression
GO:0045666  positive regulation of neuron differentiation
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0050821  protein stabilization
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0042493  response to drug
GO:0032496  response to lipopolysaccharide
GO:0033077  T cell differentiation in the thymus
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0000788  nuclear nucleosome
GO:0005634  nucleus
GO:0043234  protein complex
GO:0005667  transcription factor complex

Molecular Function

GO:0043425  bHLH transcription factor binding
GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0070888  E-box binding
GO:0031435  mitogen-activated protein kinase kinase kinase binding
GO:0030165  PDZ domain binding
GO:0005515  protein binding
GO:0046983  protein dimerization activity
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0043565  sequence-specific DNA binding
GO:0003713  transcription coactivator activity
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding
GO:0070491  transcription repressor binding
GO:0070644  vitamin D response element binding