transforming growth factor, beta 2

同義遺伝子名

Tgf-beta2, transforming growth factor, beta 2, Tgfb2, Transforming growth factor beta-2 precursor, Tgfb-2, TGF-beta-2, BB105277

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:41.70

小脳:257.90

脳幹:-

脳梁:-

松果体:257.80

末梢神経:133.80

脊柱:-

網膜:225

目:159.60

動脈:337.60

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:19.80

骨髄:-

脂肪:-

骨:50.10

皮膚:110.80

GeneChip

大脳:6.55

小脳:5.63

脳幹:-

脳梁:-

松果体:-

末梢神経:6.23

脊柱:6.49

網膜:7.67

目:9.20

動脈:-

静脈:10.01

リンパ節:4.75

末梢血:-

脾臓:4.76

胸腺:-

骨髄:4.27

脂肪:6.43

骨:6.13

皮膚:6.47

CAGE

大脳:3.33

小脳:-

脳幹:2.74

脳梁:-

松果体:-

末梢神経:-

脊柱:3.13

網膜:-

目:-

動脈:4.09

静脈:-

リンパ節:1.86

末梢血:-

脾臓:0.71

胸腺:1.80

骨髄:-

脂肪:-

骨:2.66

皮膚:4.25

RNA-seq

大脳:1.47

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:87.20

胎盤:41.40

前立腺:30.90

卵巣:333.20

精巣:44.30

心臓:130.20

骨格筋:177.50

食道:-

胃:32.70

腸:-

結腸:-

肝臓:-

肺:100.40

膀胱:198.50

腎臓:40.30

下垂体:193.80

甲状腺:-

副腎:-

膵臓:56.30

乳腺:78.40

唾液腺:54

GeneChip

子宮:6.82

胎盤:9.13

前立腺:7.98

卵巣:6.96

精巣:4.43

心臓:6.83

骨格筋:7.67

食道:-

胃:5.57

腸:5.61

結腸:-

肝臓:4.57

肺:7.67

膀胱:8.80

腎臓:5.05

下垂体:5.49

甲状腺:-

副腎:5.22

膵臓:5.03

乳腺:7.70

唾液腺:8.81

CAGE

子宮:3.63

胎盤:5.10

前立腺:3.92

卵巣:3.24

精巣:0

心臓:-

骨格筋:-

食道:-

胃:2.79

腸:2.45

結腸:1.85

肝臓:1.12

肺:3.81

膀胱:4.24

腎臓:-

下垂体:1.86

甲状腺:-

副腎:1.92

膵臓:2.83

乳腺:4.05

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.61

食道:-

胃:-

腸:-

結腸:-

肝臓:0.62

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_009367
Gene ID	21808
Unigene ID	Mm.18213
Probe set ID	1423250_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000039239

オーソログ対応遺伝子

ヒト[6]	NM_001135599, NM_003238
ラット[1]	NM_031131, NM_003238

染色体

遺伝子ファミリー (Interpro ID)

IPR001111	Transforming growth factor beta (TGFb), N-terminal
IPR015618	Transforming growth factor beta 3
IPR003911	Transforming growth factor beta TGFb
IPR003940	Transforming growth factor, beta 2
IPR016319	Transforming growth factor-beta
IPR015615	Transforming growth factor-beta-related

遺伝子オントロジー (GO ID)

Biological Process

GO:0032147	activation of protein kinase activity
GO:0007411	axon guidance
GO:0001568	blood vessel development
GO:0001974	blood vessel remodeling
GO:0060317	cardiac epithelial to mesenchymal transition
GO:0003214	cardiac left ventricle morphogenesis
GO:0060038	cardiac muscle cell proliferation
GO:0003215	cardiac right ventricle morphogenesis
GO:0010002	cardioblast differentiation
GO:0001502	cartilage condensation
GO:0042637	catagen
GO:0007050	cell cycle arrest
GO:0008219	cell death
GO:0016049	cell growth
GO:0016477	cell migration
GO:0000902	cell morphogenesis
GO:0045216	cell-cell junction organization
GO:0030199	collagen fibril organization
GO:0042416	dopamine biosynthetic process
GO:0048702	embryonic neurocranium morphogenesis
GO:0001837	epithelial to mesenchymal transition
GO:0030198	extracellular matrix organization
GO:0001654	eye development
GO:0008347	glial cell migration
GO:0040007	growth
GO:0001942	hair follicle development
GO:0031069	hair follicle morphogenesis
GO:0007507	heart development
GO:0003007	heart morphogenesis
GO:0030097	hemopoiesis
GO:0010693	negative regulation of alkaline phosphatase activity
GO:0043066	negative regulation of apoptosis
GO:0030308	negative regulation of cell growth
GO:0008285	negative regulation of cell proliferation
GO:0050680	negative regulation of epithelial cell proliferation
GO:0050777	negative regulation of immune response
GO:0045617	negative regulation of keratinocyte differentiation
GO:0010936	negative regulation of macrophage cytokine production
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol
GO:0048666	neuron development
GO:0048663	neuron fate commitment
GO:0003151	outflow tract morphogenesis
GO:0060389	pathway-restricted SMAD protein phosphorylation
GO:0070237	positive regulation of activation-induced cell death of T cells
GO:0043065	positive regulation of apoptosis
GO:0051891	positive regulation of cardioblast differentiation
GO:0051795	positive regulation of catagen
GO:0033630	positive regulation of cell adhesion mediated by integrin
GO:0045787	positive regulation of cell cycle
GO:0051781	positive regulation of cell division
GO:0030307	positive regulation of cell growth
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0010634	positive regulation of epithelial cell migration
GO:0010718	positive regulation of epithelial to mesenchymal transition
GO:0010628	positive regulation of gene expression
GO:0045823	positive regulation of heart contraction
GO:0045726	positive regulation of integrin biosynthetic process
GO:0043525	positive regulation of neuron apoptosis
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0050714	positive regulation of protein secretion
GO:0032874	positive regulation of stress-activated MAPK cascade
GO:0006468	protein amino acid phosphorylation
GO:0042981	regulation of apoptosis
GO:0032909	regulation of transforming growth factor-beta2 production
GO:0042493	response to drug
GO:0043627	response to estrogen stimulus
GO:0001666	response to hypoxia
GO:0032570	response to progesterone stimulus
GO:0001501	skeletal system development
GO:0007184	SMAD protein nuclear translocation
GO:0048103	somatic stem cell division
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0060412	ventricular septum morphogenesis
GO:0042060	wound healing

Cellular Component

GO:0030424	axon
GO:0005604	basement membrane
GO:0043025	cell soma
GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0031012	extracellular matrix
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0030141	secretory granule
GO:0005802	trans-Golgi network

Molecular Function

GO:0001540	beta-amyloid binding
GO:0008083	growth factor activity
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity
GO:0047485	protein N-terminus binding
GO:0005102	receptor binding
GO:0004702	receptor signaling protein serine/threonine kinase activity
GO:0005160	transforming growth factor beta receptor binding
GO:0005114	type II transforming growth factor beta receptor binding

transforming growth factor, beta 2

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function